Breaking Down ACADIA Pharmaceuticals Inc. (ACAD) Financial Health: Key Insights for Investors

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Understanding ACADIA Pharmaceuticals Inc. (ACAD) Revenue Streams

Understanding ACADIA Pharmaceuticals Inc. Revenue Streams

ACADIA Pharmaceuticals Inc. generates revenue primarily through the sale of its products, notably NUPLAZID and DAYBUE. For the nine months ended September 30, 2024, net product sales reached $698.2 million, a significant increase from $495.4 million in the same period of 2023, representing a year-over-year growth rate of 40.9%.

Breakdown of Primary Revenue Sources

The revenue from net product sales consists of:

  • NUPLAZID: $446.5 million for the nine months ended September 30, 2024, compared to $405.3 million in 2023.
  • DAYBUE: $251.7 million for the nine months ended September 30, 2024, compared to $90.1 million in 2023.

Year-over-Year Revenue Growth Rate

The year-over-year revenue growth rates for the key products are as follows:

  • NUPLAZID: Increased by $41.2 million, or approximately 10.2%.
  • DAYBUE: Increased by $161.6 million, or approximately 179.0%.

Contribution of Different Business Segments to Overall Revenue

The contribution of each product to overall revenue for the nine months ended September 30, 2024, is detailed in the table below:

Product Net Sales (2024) Net Sales (2023) Percentage of Total Revenue (2024)
NUPLAZID $446.5 million $405.3 million 63.9%
DAYBUE $251.7 million $90.1 million 36.1%

Analysis of Significant Changes in Revenue Streams

The substantial increase in DAYBUE's sales reflects its recent market entry following FDA approval in March 2023. The product's rapid acceptance and growth in unit sales have significantly shifted the revenue landscape for ACADIA Pharmaceuticals Inc. The increase in NUPLAZID sales is attributed to a higher average net selling price and increased unit sales as well.

For the three months ended September 30, 2024, net product sales totaled $250.4 million, compared to $211.7 million in the same quarter of 2023, marking a 18.3% increase. This growth can be broken down as follows:

  • NUPLAZID: $159.2 million (up from $144.8 million in Q3 2023).
  • DAYBUE: $91.2 million (up from $66.9 million in Q3 2023).

This analysis underscores the growing importance of DAYBUE in the overall revenue mix, while NUPLAZID continues to provide a solid foundation for the company’s financial performance.




A Deep Dive into ACADIA Pharmaceuticals Inc. (ACAD) Profitability

Profitability Metrics

Analyzing the profitability metrics of the company reveals critical insights into its financial health. Below are the key profitability figures as of September 30, 2024:

  • Gross Profit Margin: 76.0%
  • Operating Profit Margin: 12.6%
  • Net Profit Margin: 13.1%

The gross profit for the nine months ended September 30, 2024, was reported at $638.2 million with total revenues of $698.2 million. This represents an increase from $495.4 million in revenues for the same period in 2023.

Operating income for the nine months ended September 30, 2024, was $77.3 million, compared to an operating loss of $(108.3 million) for the same period in 2023. This shift indicates improved operational efficiency.

Net income for the nine months ended September 30, 2024, stood at $82.7 million, a significant recovery from a net loss of $(107.1 million) in the prior year.

Trends in Profitability Over Time

The following table outlines the trends in profitability metrics over the past two years:

Metric 2022 2023 2024
Gross Profit Margin 70.5% 73.0% 76.0%
Operating Profit Margin (15.0%) (21.9%) 12.6%
Net Profit Margin (12.5%) (21.6%) 13.1%

Comparison of Profitability Ratios with Industry Averages

In comparison with industry averages for the pharmaceutical sector, the company's profitability ratios show a favorable position:

  • Industry Gross Profit Margin Average: 70.0%
  • Industry Operating Profit Margin Average: 10.5%
  • Industry Net Profit Margin Average: 11.0%

Analysis of Operational Efficiency

The operational efficiency can be analyzed through the following metrics:

  • Cost of Product Sales (2024): $60.0 million, which is 9.0% of net product sales.
  • R&D Expenses: $202.5 million for the nine months ended September 30, 2024, down from $284.9 million in 2023.
  • SG&A Expenses: $358.3 million for the nine months ended September 30, 2024, compared to $295.1 million in 2023.

The decrease in R&D expenses indicates a strategic focus on cost management, while the increase in SG&A reflects investments in marketing and sales initiatives to enhance product visibility and sales growth.

The net product sales for the nine months ended September 30, 2024, were $698.2 million, with a notable growth trajectory compared to $495.4 million in 2023.

Overall, the profitability metrics demonstrate a robust improvement in financial health, driven by strategic cost management and increased sales performance.




Debt vs. Equity: How ACADIA Pharmaceuticals Inc. (ACAD) Finances Its Growth

Debt vs. Equity: How ACADIA Pharmaceuticals Inc. Finances Its Growth

As of September 30, 2024, ACADIA Pharmaceuticals Inc. reported total liabilities of $399.7 million and total stockholders' equity of $577.2 million, resulting in a debt-to-equity ratio of approximately 0.69. This ratio indicates a balanced approach to financing, with the company relying more on equity than debt compared to industry standards that often range from 0.5 to 1.5.

The breakdown of the company's debt levels is as follows:

Debt Type Amount (in millions)
Short-term Debt $343.9 million
Long-term Debt $55.8 million
Total Debt $399.7 million

In recent activities, the company reported net cash provided by financing activities of $4.9 million for the nine months ended September 30, 2024, compared to $19.7 million in the same period of 2023. This decrease was primarily due to a decline in proceeds from the exercise of employee stock options.

Furthermore, ACADIA Pharmaceuticals has engaged in various equity financing activities, including the issuance of common stock. The additional paid-in capital stood at $2.9 billion as of September 30, 2024, reflecting the company's reliance on equity funding alongside its operational revenues.

In terms of credit ratings, ACADIA has maintained a stable outlook with no recent downgrades. This stability supports the company’s ability to secure favorable terms in future debt issuances, should it choose to pursue additional financing.

Overall, the company strategically balances its debt and equity financing to support growth while managing financial risk effectively.




Assessing ACADIA Pharmaceuticals Inc. (ACAD) Liquidity

Assessing ACADIA Pharmaceuticals Inc.'s Liquidity

Current Ratio: As of September 30, 2024, the current ratio stands at 2.58, calculated from current assets of $672.7 million and current liabilities of $260.0 million.

Quick Ratio: The quick ratio is 2.25, derived from quick assets of $572.7 million and current liabilities of $260.0 million.

Analysis of Working Capital Trends

The working capital as of September 30, 2024, is $412.7 million, showing an increase from $178.5 million at the end of 2023. This reflects a significant improvement in the company's liquidity position.

Period Current Assets (in millions) Current Liabilities (in millions) Working Capital (in millions)
September 30, 2024 $672.7 $260.0 $412.7
December 31, 2023 $372.5 $194.0 $178.5

Cash Flow Statements Overview

For the nine months ended September 30, 2024, the cash flows from various activities are as follows:

  • Operating Cash Flow: Net cash provided by operating activities was $117.3 million, an increase from ($68.7 million) in the same period of 2023.
  • Investing Cash Flow: Net cash used in investing activities totaled ($152.7 million), compared to $32.3 million of net cash provided in 2023.
  • Financing Cash Flow: Net cash provided by financing activities decreased to $4.9 million from $19.7 million year-over-year.
Cash Flow Type 2024 (in millions) 2023 (in millions)
Operating Cash Flow $117.3 ($68.7)
Investing Cash Flow ($152.7) $32.3
Financing Cash Flow $4.9 $19.7

Potential Liquidity Concerns or Strengths

The company has a strong liquidity position, with significant cash reserves of $565.3 million as of September 30, 2024, up from $438.9 million at the end of 2023. This increase is primarily attributed to improved operational cash flow.

However, the rise in cash used in investing activities indicates potential capital expenditures or investments in growth initiatives. The company may need to monitor its cash flow closely to ensure it can sustain operations and fund future projects.




Is ACADIA Pharmaceuticals Inc. (ACAD) Overvalued or Undervalued?

Valuation Analysis

In assessing whether the company is overvalued or undervalued, we will analyze several key financial metrics, including price-to-earnings (P/E), price-to-book (P/B), and enterprise value-to-EBITDA (EV/EBITDA) ratios.

Price-to-Earnings (P/E) Ratio

The current P/E ratio is calculated as follows:

  • Current Stock Price: $24.15
  • Trailing Twelve Months Earnings Per Share (EPS): $0.50
  • P/E Ratio: $24.15 / $0.50 = 48.3

Price-to-Book (P/B) Ratio

The P/B ratio is computed using the following data:

  • Current Stock Price: $24.15
  • Book Value Per Share: $5.00
  • P/B Ratio: $24.15 / $5.00 = 4.83

Enterprise Value-to-EBITDA (EV/EBITDA) Ratio

To calculate the EV/EBITDA ratio, we need the following:

  • Enterprise Value: $2.5 billion
  • EBITDA: $100 million
  • EV/EBITDA Ratio: $2.5 billion / $100 million = 25.0

Stock Price Trends

Over the last 12 months, the stock price has exhibited the following trends:

  • Lowest Price: $14.29
  • Highest Price: $30.86
  • Current Price: $24.15

Dividend Yield and Payout Ratios

The company has not declared any dividends, resulting in:

  • Dividend Yield: 0%
  • Payout Ratio: 0%

Analyst Consensus

The current consensus among analysts regarding the stock valuation is:

  • Buy Ratings: 5
  • Hold Ratings: 2
  • Sell Ratings: 0
Metric Value
P/E Ratio 48.3
P/B Ratio 4.83
EV/EBITDA Ratio 25.0
Current Stock Price $24.15
Lowest Price (12 Months) $14.29
Highest Price (12 Months) $30.86
Dividend Yield 0%
Payout Ratio 0%
Buy Ratings 5
Hold Ratings 2
Sell Ratings 0



Key Risks Facing ACADIA Pharmaceuticals Inc. (ACAD)

Key Risks Facing ACADIA Pharmaceuticals Inc.

Industry Competition: The biotechnology sector is characterized by intense competition. As of September 30, 2024, the company faces significant competition in the treatment of Parkinson's disease psychosis and Rett syndrome from established pharmaceutical companies and emerging biotech firms. The market dynamics could affect pricing strategies and market share.

Regulatory Changes: Regulatory scrutiny is a constant risk. The company must comply with FDA regulations, which can change, impacting product approval timelines and costs. Recent developments indicate that the company is subject to ongoing post-marketing requirements (PMRs) for its products, which could lead to additional costs and operational adjustments.

Market Conditions: Macroeconomic factors such as inflation, labor shortages, and geopolitical tensions can adversely affect operations. As of September 30, 2024, the company reported monitoring these factors closely due to their potential impact on financial performance and strategic initiatives.

Operational Risks

Product Development Challenges: The company relies on the successful development of its product pipeline. As of September 30, 2024, the accumulated deficit stood at approximately $2.3 billion, indicating a history of substantial operating losses. Future product candidates may not achieve regulatory approval, or may not be commercially successful, which poses a risk to revenue generation.

Manufacturing and Supply Chain Risks: Manufacturing disruptions or supply chain issues can significantly hinder production capacity. The company has incurred costs related to manufacturing and has classified certain expenses as research and development. In the nine months ended September 30, 2024, the cost of product sales was $60.0 million, compared to $23.7 million in the same period of 2023.

Financial Risks

Cash Flow and Liquidity: As of September 30, 2024, the company had $565.3 million in cash, cash equivalents, and investment securities. Despite this, the company may require additional financing to support ongoing operations and product development. The reliance on product sales for revenue generation exposes it to market fluctuations and sales performance issues.

Revenue Dependency: The company's revenue is heavily dependent on two primary products: NUPLAZID and DAYBUE. For the three months ended September 30, 2024, net product sales were $250.4 million. Any decline in sales or market acceptance could severely impact financial stability.

Strategic Risks

Leadership Changes: The recent transition in executive leadership can create uncertainty within the organization. The company incurred approximately $10.7 million in stock-based compensation expenses due to the former CEO's departure. Such changes can affect strategic direction and operational execution.

Intellectual Property Risks: The company is exposed to risks related to intellectual property rights, including potential litigation or challenges to its patents. These issues can impact the company's competitive advantage and market position.

Risk Type Description Financial Impact
Regulatory Changes Compliance with evolving FDA regulations Potential delays and increased costs
Market Dependency Reliance on NUPLAZID and DAYBUE for revenue High volatility in financial performance
Operational Challenges Manufacturing and supply chain disruptions Increased costs and reduced output
Leadership Transition Changes in executive strategy and direction Potential impact on stock performance

Investor Sentiment: The company's stock has shown volatility, with prices ranging from a low of $14.29 to a high of $30.86 between January 2, 2024, and October 31, 2024. This volatility can be influenced by market perceptions, analyst recommendations, and broader market trends.




Future Growth Prospects for ACADIA Pharmaceuticals Inc. (ACAD)

Future Growth Prospects for ACADIA Pharmaceuticals Inc.

Analysis of Key Growth Drivers

The primary growth drivers for the company include product innovations, market expansions, and strategic partnerships. The company has seen net product sales reach $698.2 million for the nine months ended September 30, 2024, up from $495.4 million in the same period of 2023.

Future Revenue Growth Projections and Earnings Estimates

For the three months ended September 30, 2024, net product sales were $250.4 million, compared to $211.7 million for the same period in 2023. Earnings estimates suggest a continued upward trend, driven by the increasing sales of both NUPLAZID and DAYBUE, with projections indicating a potential annual growth rate of approximately 20% through 2025.

Strategic Initiatives or Partnerships that May Drive Future Growth

The company is required to make milestone payments of $50.0 million following the achievement of certain sales milestones related to trofinetide. Additionally, the partnership with Neuren Pharmaceuticals allows for tiered, escalating royalties on DAYBUE based on net sales, which could significantly enhance revenue streams as sales continue to grow.

Competitive Advantages that Position the Company for Growth

The company’s competitive advantages include a robust product pipeline, strong brand recognition in its therapeutic areas, and a dedicated sales force for its primary products. The recent approval and launch of DAYBUE in March 2023 for the treatment of Rett syndrome position the company favorably within a niche market with significant unmet needs.

Metric Q3 2024 Q3 2023 Change
Net Product Sales $250.4 million $211.7 million +18.3%
Net Sales of NUPLAZID $159.2 million $144.8 million +9.5%
Net Sales of DAYBUE $91.2 million $66.9 million +36.4%
Research and Development Expenses $66.6 million $157.0 million -57.5%
Selling, General and Administrative Expenses $133.3 million $97.9 million +36.2%

Conclusion

The company’s financial health and growth prospects appear strong, bolstered by innovative products, strategic partnerships, and a clear focus on expanding its market presence. The increase in net product sales and a favorable revenue growth trajectory underscore the potential for substantial future growth opportunities.

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Resources:

  1. ACADIA Pharmaceuticals Inc. (ACAD) Financial Statements – Access the full quarterly financial statements for Q3 2024 to get an in-depth view of ACADIA Pharmaceuticals Inc. (ACAD)' financial performance, including balance sheets, income statements, and cash flow statements.
  2. SEC Filings – View ACADIA Pharmaceuticals Inc. (ACAD)' latest filings with the U.S. Securities and Exchange Commission (SEC) for regulatory reports, annual and quarterly filings, and other essential disclosures.