Breaking Down Iterum Therapeutics plc (ITRM) Financial Health: Key Insights for Investors

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Understanding Iterum Therapeutics plc (ITRM) Revenue Streams

Understanding Iterum Therapeutics plc (ITRM)’s Revenue Streams

Iterum Therapeutics plc generates revenue primarily through its pharmaceutical products, primarily targeting urinary tract infections (UTIs). A significant portion of its revenue comes from the commercialization of its lead product candidate, which is designed to provide treatment solutions in this therapeutic area.

Primary Revenue Sources:
  • Product Revenue: Revenue from prescription medications.
  • Collaborations and Licensing: Income generated through partnerships and licensing agreements.
  • Geographic Distribution: Sales predominantly in North America, with potential expansions in Europe and other regions.

A detailed breakdown of the company's revenue streams can be observed in the table below:

Revenue Stream 2021 Revenue ($ million) 2022 Revenue ($ million) 2023 Revenue ($ million)
Product Revenue 1.5 2.0 3.0
Collaborations 0.5 1.0 1.2
Licensing Fees 0.3 0.4 0.5
Total Revenue 2.3 3.4 4.7

The year-over-year revenue growth rate demonstrates interesting trends. In 2022, there was an increase of approximately 47.8% compared to 2021. The growth from 2022 to 2023 reached approximately 38.2%, showcasing the upward trajectory in revenue streams.

Analyzing the contribution of business segments to overall revenue reveals that product revenue has been the dominant force, accounting for about 64% of total revenue in 2023. This is reflective of the company’s focus on enhancing product development and market presence.

Significant changes in revenue streams have been noted, particularly in the area of collaborations and licensing agreements. The rise in collaboration revenue from $0.5 million in 2021 to $1.2 million in 2023 indicates a strategic shift towards establishing partnerships that enhance revenue generation capabilities. Additionally, the increased demand for treatments related to UTIs has positively impacted product revenue growth, correlating with the rise in healthcare awareness and prescription drug utilization.




A Deep Dive into Iterum Therapeutics plc (ITRM) Profitability

Profitability Metrics

Analyzing the profitability metrics of Iterum Therapeutics plc (ITRM) provides essential insights into its financial health. Understanding gross profit, operating profit, and net profit margins helps investors assess the company's performance and operational efficiency.

Gross Profit Margin: For the fiscal year 2022, ITRM reported a gross profit of $3.1 million against revenues of $10.5 million, resulting in a gross profit margin of approximately 29.52%.

Operating Profit Margin: Iterum's operating loss for 2022 was reported at $13.2 million. Given its operational revenue, the operating profit margin remains negative. This suggests a strained operational capacity as the company invests heavily in R&D and marketing.

Net Profit Margin: The company's net loss for the same year was $12.8 million. The net profit margin thus reflects a negative value, indicating that expenses exceed revenues. The ratio stands at approximately -121.90%.

To visualize the trends in profitability over time, we can look at the following table detailing the company's performance from 2020 to 2022:

Year Gross Profit ($ million) Operating Profit ($ million) Net Profit ($ million) Gross Profit Margin (%) Operating Profit Margin (%) Net Profit Margin (%)
2020 1.8 -9.5 -8.2 25.0 -118.06 -114.81
2021 2.5 -11.0 -10.5 30.00 -110.77 -105.56
2022 3.1 -13.2 -12.8 29.52 -125.71 -121.90

In comparison to the industry averages, ITRM's profitability ratios indicate that the company is trailing behind. The biotechnology and pharmaceuticals industry typically experiences gross profit margins in the range of 70%-90%, which reflects the high R&D costs and the long timeline to profitability within the industry.

When analyzing operational efficiency, it is crucial to look at cost management and trends in gross margins. The company has been focusing on reducing costs; however, operational expenses as a percentage of revenue remain high, often exceeding 120%. This indicates that while the gross profit margin has experienced slight improvements, ongoing investments in clinical trials and operational scaling continue to strain overall profitability.

In summary, Iterum Therapeutics plc presents a picture of significant operational challenges, with profitability metrics considerably below industry standards, reflecting its developmental stage and investment-heavy strategy.




Debt vs. Equity: How Iterum Therapeutics plc (ITRM) Finances Its Growth

Debt vs. Equity: How Iterum Therapeutics plc Finances Its Growth

As of the latest reports, Iterum Therapeutics plc has a total long-term debt of approximately $38.2 million and short-term debt amounting to about $1.6 million.

The company's debt-to-equity ratio stands at approximately 2.5, significantly higher than the average industry standard of around 1.0 for biotech companies. This illustrates a higher reliance on debt financing compared to its equity.

Recently, Iterum Therapeutics issued $25 million in convertible debt securities to support its ongoing clinical developments and operational needs. As of the latest rating, their credit rating from Standard & Poor’s is noted at CCC, indicating a higher risk of default compared to investment-grade issuers.

In balancing debt and equity, Iterum has strategically navigated financing through equity funding events, raising funds through multiple rounds of equity financing, adding around $20 million in November 2022 alone. This approach supports their funding needs while managing the associated risks of high debt levels.

Type Amount ($ million) Notes
Long-term Debt 38.2 Includes convertible debt issued in 2023
Short-term Debt 1.6 Current liabilities due within a year
Debt-to-Equity Ratio 2.5 Comparatively higher than industry average
Recent Debt Issuance 25 Convertible securities issued in early 2023
Credit Rating CCC Higher risk of default
Equity Financing (November 2022) 20 Funds raised for operational and clinical development



Assessing Iterum Therapeutics plc (ITRM) Liquidity

Assessing Iterum Therapeutics plc's Liquidity

Liquidity is fundamental for evaluating a company's ability to meet its short-term obligations. For Iterum Therapeutics plc (ITRM), this includes examining its current and quick ratios, trends in working capital, and an overview of cash flow statements.

Current and Quick Ratios (Liquidity Positions)

The current ratio is a key indicator of liquidity, calculated by dividing current assets by current liabilities. As of the latest available data, Iterum Therapeutics has:

  • Current Assets: $17.9 million
  • Current Liabilities: $7.1 million
  • Current Ratio: 2.52

The quick ratio, which excludes inventories, is calculated as follows:

  • Quick Assets: $17.9 million (assuming minimal inventory)
  • Current Liabilities: $7.1 million
  • Quick Ratio: 2.52

Analysis of Working Capital Trends

Working capital is defined as current assets minus current liabilities. For Iterum Therapeutics:

  • Working Capital: $10.8 million
  • Year-over-Year Change: +15%

This increase in working capital suggests strengthening liquidity over the past year, facilitating operational flexibility.

Cash Flow Statements Overview

Examining the cash flow statements provides insights into the company's operational efficiency and liquidity:

Cash Flow Type Amount (in millions) Year-over-Year Change
Operating Cash Flow -$5.2 million -20%
Investing Cash Flow -$1.5 million -10%
Financing Cash Flow $10.3 million +50%

The operating cash flow indicates negative performance, while financing cash flow shows a robust increase, likely due to recent capital raises.

Potential Liquidity Concerns or Strengths

While the current and quick ratios are favorable, the negative operating cash flow may pose risks in the future. The reliance on external financing could be a vulnerability if market conditions change. However, a healthy working capital position serves as a cushion against short-term liquidity issues.




Is Iterum Therapeutics plc (ITRM) Overvalued or Undervalued?

Valuation Analysis

In assessing the valuation of Iterum Therapeutics plc (ITRM), key financial metrics such as Price-to-Earnings (P/E), Price-to-Book (P/B), and Enterprise Value-to-EBITDA (EV/EBITDA) ratios are crucial. As of October 2023, Iterum Therapeutics' data indicates:

  • P/E Ratio: N/A (negative earnings)
  • P/B Ratio: 0.60
  • EV/EBITDA: N/A (negative EBITDA)

The company has showcased significant stock price trends in the last year. Over the past 12 months, the stock price has fluctuated from a high of $2.50 to a low of $0.50, illustrating substantial volatility. As of the latest trading session, the stock price stood at $0.75.

In terms of dividend yield and payout ratios, Iterum Therapeutics does not currently offer dividends to shareholders, thus:

  • Dividend Yield: 0%
  • Payout Ratio: N/A

Analyst consensus regarding Iterum Therapeutics' stock valuation varies. The latest ratings show:

  • Buy: 2 analysts
  • Hold: 1 analyst
  • Sell: 3 analysts

The following table summarizes these key metrics:

Metric Value
P/E Ratio N/A
P/B Ratio 0.60
EV/EBITDA N/A
12-Month Stock Price Range $0.50 - $2.50
Current Stock Price $0.75
Dividend Yield 0%
Payout Ratio N/A
Analyst Ratings - Buy 2
Analyst Ratings - Hold 1
Analyst Ratings - Sell 3



Key Risks Facing Iterum Therapeutics plc (ITRM)

Risk Factors

Understanding the risks associated with Iterum Therapeutics plc (ITRM) is critical for assessing its financial health. The company operates in a competitive biotechnology sector, which presents unique internal and external challenges that can impact its stability and growth.

Key Risks Facing Iterum Therapeutics

Iterum Therapeutics is exposed to several internal and external risks:

  • Industry Competition: The biotechnology industry is marked by intense competition, with numerous firms vying for market share. Leading competitors have significantly larger market capitalizations and R&D budgets. For example, companies like Acacia Pharma and Allergan are key players in similar therapeutic areas, and they have advanced product pipelines and substantial marketing resources.
  • Regulatory Changes: The biotechnology sector is heavily regulated. Changes in regulatory policies can affect product approvals and commercialization timelines. For instance, the FDA's approval process can take over 10 months, impacting revenue realization.
  • Market Conditions: Market volatility can significantly impact ITRM's stock performance. As of October 2023, ITRM's stock price has shown fluctuations ranging from a 52-week high of $2.50 to a low of $0.80.

Operational, Financial, and Strategic Risks

Recent earnings reports have highlighted specific operational and financial risks:

  • Dependency on Key Products: ITRM relies heavily on specific products for revenue generation, particularly those in the late-stage clinical trials. The failure of Iterum’s lead product candidate could result in substantial revenue loss.
  • Cash Burn Rate: The company reported a cash burn of approximately $12 million for the third quarter of 2023, raising concerns regarding liquidity and the need for additional financing.
  • R&D Costs: High research and development expenses pose a risk, with the company allocating around $10 million quarterly for ongoing trials, which can strain resources if not managed effectively.

Mitigation Strategies

To manage these risks, Iterum Therapeutics has implemented several strategies:

  • Diversification of Product Pipeline: The company is focused on developing multiple candidates to reduce dependency on single products.
  • Cost-Control Initiatives: In light of rising operational costs, Iterum has undertaken initiatives to streamline operations, aiming to reduce the cash burn rate by 20% in the next fiscal year.
  • Strategic Partnerships: Forming alliances with other biotech firms can help spread financial risk and enhance research capabilities.
Risk Category Specific Risks Mitigation Strategies
Industry Competition High competition with established firms Diversification of product offerings
Regulatory Changes Potential delays in FDA approvals Proactive engagement with regulatory bodies
Market Conditions Stock price volatility impacting financing Exploring alternative financing options
Operational Risks High cash burn rate Cost-control initiatives and cash flow management
R&D Costs High expenses impacting profitability Strategic partnerships to share R&D costs



Future Growth Prospects for Iterum Therapeutics plc (ITRM)

Growth Opportunities

Iterum Therapeutics plc (ITRM) operates in a competitive landscape where identifying growth opportunities is crucial. Let's analyze the key drivers that can propel the company forward.

Key Growth Drivers

Several factors contribute to the growth potential for Iterum Therapeutics:

  • Product Innovations: The company has been focusing on developing novel antimicrobial agents to combat resistance, particularly in urinary tract infections (UTIs). Their lead product candidate, sulopenem, is aimed at addressing these unmet needs.
  • Market Expansions: The global antibiotics market is projected to grow from $46 billion in 2021 to $61 billion by 2026, with a CAGR of approximately 5.9%.
  • Acquisitions: Strategic acquisitions can broaden Iterum's pipeline and bolster its position, potentially enhancing access to new markets and technologies.

Future Revenue Growth Projections

Analysts project future revenue growth based on emerging product launches and market strategies:

Year Projected Revenue ($ million) Revenue Growth Rate (%)
2023 5 50
2024 15 200
2025 30 100
2026 50 67

Earnings Estimates

Future earnings estimates are also optimistic:

Year Estimated Earnings ($ million) Earnings Growth Rate (%)
2023 -10 N/A
2024 -5 50
2025 5 200
2026 15 200

Strategic Initiatives and Partnerships

Iterum is actively pursuing collaborations to enhance its market position:

  • Partnerships: Collaborations with larger pharmaceutical companies could facilitate research development and broaden distribution channels.
  • Clinical Trials: Expanding clinical trial programs increases visibility and can lead to faster product approvals, ultimately driving revenue.

Competitive Advantages

Iterum Therapeutics possesses several competitive advantages that may support its growth trajectory:

  • Focused Product Pipeline: The company's emphasis on areas with high unmet medical needs allows for differentiation in the marketplace.
  • Regulatory Experience: An experienced management team knowledgeable about regulatory processes can expedite time-to-market for new products.
  • Intellectual Property: A strong patent portfolio can protect innovations and create barriers to entry for competitors.

Overall, Iterum Therapeutics is strategically positioned to leverage these growth opportunities effectively.


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