Deciphera Pharmaceuticals, Inc. (DCPH) Bundle
A Brief History of Deciphera Pharmaceuticals, Inc. (DCPH)
Foundation and Early Development
Deciphera Pharmaceuticals, Inc. was founded in 2003, focusing on developing innovative therapies for cancer. The company's headquarters is located in Waltham, Massachusetts. Initial funding raised in 2003 amounted to approximately $16 million.
Public Offering and Growth
In 2018, Deciphera went public with an initial public offering (IPO) that raised around $120 million. The share price during the IPO was set at $18.00 per share. The gross proceeds from the offering were intended to advance their clinical programs and support research and development efforts.
Key Products and Developments
Deciphera’s lead product candidate, DCC-2618, targets specific mutations in the KIT and PDGFRA genes, particularly for gastrointestinal stromal tumors (GIST). In 2020, DCC-2618 received FDA approval for the treatment of adult patients with GIST after progression on or intolerance to prior therapy.
For the fiscal year 2022, the company reported total revenue of approximately $79.8 million, an increase from $68.4 million in 2021. The revenue primarily stemmed from sales of DCC-2618, which contributed approximately $72.5 million in 2022.
Financial Overview
As of the fiscal year ending December 31, 2022, Deciphera Pharmaceuticals reported the following key financial metrics:
Metric | 2022 Amount | 2021 Amount |
---|---|---|
Total Revenue | $79.8 million | $68.4 million |
Net Loss | $(162.2) million | $(140.2) million |
Research and Development Expenses | $96.5 million | $83.6 million |
Cash and Cash Equivalents | $163.7 million | $195.4 million |
Strategic Collaborations and Partnerships
Deciphera has entered into multiple collaborations, notably with large pharmaceutical firms for the development and commercialization of its products. In September 2021, Deciphera announced a collaboration with Blueprint Medicines for the development of next-generation therapies, significantly enhancing its R&D capabilities.
Market Position and Stock Performance
As of October 2023, Deciphera Pharmaceuticals trades on the NASDAQ under the ticker symbol DCPH. The market capitalization of Deciphera was approximately $470 million. The stock has experienced fluctuations, with a 52-week range between $2.30 and $5.50 per share.
Recent Developments
In 2023, Deciphera Pharmaceuticals announced the initiation of Phase 1 clinical trials for its new product candidate, aiming to expand its pipeline targeting additional oncology indications. The company expects to present preliminary data in late 2023.
Future Outlook
Deciphera Pharmaceuticals has signaled plans to continue focusing on clinical trials and seeks to deliver innovative oncology treatments. The company aims for an expanded presence in the oncology market and plans to utilize its existing cash reserves to support ongoing research and development.
A Who Owns Deciphera Pharmaceuticals, Inc. (DCPH)
Shareholder Composition
Deciphera Pharmaceuticals, Inc. (DCPH) has a diverse shareholder base comprising institutional investors, individual shareholders, and company insiders. The following table summarizes the ownership breakdown as of the latest data available in 2023.
Shareholder Type | % Ownership | Number of Shares Owned | Shareholder Count |
---|---|---|---|
Institutional Investors | 75% | 22,500,000 | 85 |
Insiders | 10% | 3,000,000 | 10 |
Individual Investors | 15% | 4,500,000 | 1,200 |
Major Institutional Investors
Significant institutional investors play a key role in Deciphera Pharmaceuticals’ stock distribution. The following table lists the top institutional shareholders as of October 2023.
Institution Name | % Ownership | Number of Shares Owned |
---|---|---|
BlackRock, Inc. | 12% | 3,600,000 |
The Vanguard Group, Inc. | 10% | 3,000,000 |
Fidelity Investments | 8% | 2,400,000 |
State Street Corporation | 7% | 2,100,000 |
Insider Ownership
The insider ownership of Deciphera Pharmaceuticals reflects confidence from its management team. Below are details regarding the top insiders and their shareholdings.
Name | Title | % Ownership | Number of Shares Owned |
---|---|---|---|
Michael D. Taylor | CEO | 3% | 900,000 |
Shawn M. Marcell | COO | 2% | 600,000 |
Gregory W. P. Foster | CFO | 1.5% | 450,000 |
Recent Financial Performance
As of Q3 2023, Deciphera Pharmaceuticals reported financial results indicating its operational health and stock performance. The following table presents key financial metrics from the latest quarterly earnings.
Metric | Value |
---|---|
Total Revenue | $25 million |
Net Income | ($10 million) |
Operating Expenses | $30 million |
Cash and Cash Equivalents | $150 million |
Stock Performance
Performance analysis of DCPH's stock reflects market trends and investor sentiment. Below are the current stock statistics.
Statistic | Value |
---|---|
Current Stock Price | $11.00 |
Market Capitalization | $330 million |
52-Week High | $15.00 |
52-Week Low | $7.50 |
Deciphera Pharmaceuticals, Inc. (DCPH) Mission Statement
Company Overview
Deciphera Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing innovative therapies for cancer patients. Founded in 2008, the company is headquartered in Waltham, Massachusetts.
Mission Statement
The mission of Deciphera Pharmaceuticals is to improve the lives of patients with cancer by developing next-generation therapies that target specific disease mechanisms. This focus underscores the company's commitment to precision medicine in oncology.
Core Values
- Innovation: Emphasizing research and development to create novel therapeutics.
- Patient-Centricity: Prioritizing patient needs and outcomes in all aspects of the business.
- Integrity: Maintaining ethical standards in clinical trials and corporate governance.
- Collaboration: Partnering with other organizations to enhance research and improve therapies.
Financial Performance
Year | Total Revenue | Net Income | Total Assets | Total Liabilities |
---|---|---|---|---|
2022 | $55.5 million | ($95.2 million) | $308.7 million | $87.2 million |
2021 | $19.7 million | ($89.5 million) | $207.8 million | $78.4 million |
2020 | $10.1 million | ($76.7 million) | $156.4 million | $60.5 million |
2019 | $2.4 million | ($75.1 million) | $106.2 million | $52.3 million |
Recent Milestones
In 2023, Deciphera Pharmaceuticals achieved significant milestones, including:
- FDA Approval: Received FDA approval for its lead product, Qinlock (ripretinib), for the treatment of gastrointestinal stromal tumor (GIST).
- Clinical Trials: Advanced several investigational drugs into phase 3 clinical trials, targeting various oncological indications.
- Partnerships: Formed strategic alliances with leading pharmaceutical companies for joint development initiatives.
Stock Information
As of October 2023, Deciphera Pharmaceuticals trades on the NASDAQ under the ticker symbol DCPH. The stock performance has shown significant volatility with a recent price of approximately $12.50 per share.
Market capitalization as of the latest trading session is approximately $700 million.
Research and Development Focus
Deciphera’s R&D strategy is centered on the following therapeutic areas:
- Targeted therapies for solid tumors
- Mechanism-based therapies designed to circumvent resistance
- Innovative treatment modalities for hematologic malignancies
How Deciphera Pharmaceuticals, Inc. (DCPH) Works
Company Overview
Deciphera Pharmaceuticals, Inc. (DCPH) is a biotechnology company focused on developing innovative treatments for cancer. The company is headquartered in Waltham, Massachusetts, and it specializes in precision medicines for patients with genetically defined cancers.
Key Products
Deciphera's lead product candidate is DCC-2618, an oral small molecule drug designed to target specific mutations in the PDGFRα and KIT pathways.
Product | Indication | Status | FDA Approval Date | Annual Revenue (2022) |
---|---|---|---|---|
DCC-2618 | Gastrointestinal Stromal Tumors (GIST) | Approved | December 2019 | $54.4 million |
Research and Development Pipeline
Deciphera Pharmaceuticals has a robust pipeline of product candidates. As of the end of 2023, the pipeline includes:
- DCC-3116: A selective inhibitor of CSF1R for solid tumors.
- DCC-2036: A therapeutic for patients with GIST resistant to first-line therapies.
- DCC-3014: Investigational agent for AML and other hematologic malignancies.
Financial Performance
For the fiscal year 2022, Deciphera Pharmaceuticals reported the following financial data:
Metric | Amount (2022) |
---|---|
Revenue | $54.4 million |
Net Loss | $(112.7) million |
Research and Development Expenses | $87.5 million |
General and Administrative Expenses | $30.9 million |
Market Capitalization
The market capitalization of Deciphera Pharmaceuticals as of October 2023 is approximately $400 million. The stock price has fluctuated between $5.00 and $15.00 throughout the year.
Collaboration and Partnerships
Deciphera Pharmaceuticals engages in strategic collaborations, including:
- Partnership with Merck for joint research projects.
- Collaboration with Novartis focused on biomarker discovery.
Clinical Trials
Deciphera conducts multiple clinical trials to evaluate the safety and efficacy of their products. As of late 2023, they have:
- 15 active clinical trials.
- Over 500 patients enrolled in various phases of trials.
Regulatory Overview
Deciphera Pharmaceuticals maintains compliance with regulatory bodies such as the FDA and EMA. The company has successfully navigated the following milestones:
- FDA granted Fast Track Designation for DCC-2618.
- European Commission approved DCC-2618 for marketing.
Future Outlook
Deciphera is focused on expanding its pipeline and is preparing for upcoming clinical data presentations in 2024. The company expects to initiate two new Phase 3 trials within the next year.
How Deciphera Pharmaceuticals, Inc. (DCPH) Makes Money
Revenue Sources
Revenue Sources
Deciphera Pharmaceuticals, Inc. (DCPH) derives its revenue primarily from the development and commercialization of therapeutics for cancer and other serious diseases. The company's business model includes the sales of its marketed products, milestone payments from collaborations, and grants.
Product Sales
As of the latest financial reports, DCPH's primary product is Qinlock (ripretinib), which is an FDA-approved treatment for adult patients with gastrointestinal stromal tumors (GIST). In 2022, Qinlock generated approximately $52.5 million in net product revenues.
Collaborative Agreements
Deciphera engages in strategic collaborations with other pharmaceutical companies, which include milestone payments and royalties. In 2022, DCPH reported receiving $20 million in milestone payments related to its collaborative agreements.
The company has established partnerships that enhance its pipeline, including agreements with companies such as Amgen and Bristol-Myers Squibb.
Research and Development Grants
DCPH also receives funding through government grants aimed at advancing scientific research. For the fiscal year 2022, the company reported receiving approximately $5 million in grants that support their ongoing oncology research programs.
Financial Performance Overview
The financial performance of Deciphera Pharmaceuticals is detailed as follows:
Financial Metric | 2020 | 2021 | 2022 |
---|---|---|---|
Total Revenue | $1.8 million | $17.5 million | $72.3 million |
Net Product Revenue | $0 | $0 | $52.5 million |
Collaboration Revenue | $1.8 million | $13.5 million | $20 million |
Research Grants | $0 | $3 million | $5 million |
Market Potential
The potential market for Deciphera's products is significant, especially in the oncology space. The estimated global market for GIST therapies is projected to exceed $2 billion by 2025, indicating substantial opportunities for future revenue generation.
Pipeline and Future Revenue Potential
Deciphera has several compounds in various stages of clinical development, which may contribute to future revenue streams. Key pipeline candidates include:
- DC-806: A selective inhibitor for additional cancer indications.
- DC-393: Targeting other solid tumors with unmet medical needs.
Success in clinical trials could lead to new product approvals and significant revenue generation from both product sales and potential licensing agreements.
Conclusion on Financial Outlook
With a strong focus on innovation and strategic partnerships, Deciphera Pharmaceuticals is positioned for growth. The company's emphasis on expanding its product portfolio and sustaining revenue from existing therapies will be critical for its financial success.
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