Enanta Pharmaceuticals, Inc. (ENTA) Bundle
A Brief History of Enanta Pharmaceuticals, Inc. (ENTA)
Foundation and Initial Developments
Enanta Pharmaceuticals, Inc., founded in 1995, is a biotechnology company focused primarily on developing novel therapeutics for infectious diseases and liver diseases.
Key Milestones
- 2000: Enanta went public with its initial public offering (IPO), raising approximately $30 million.
- 2003: The company achieved a significant milestone with the discovery of compounds targeting HCV (Hepatitis C Virus).
- 2012: Enanta and AbbVie entered into a collaboration agreement to develop and commercialize HCV protease inhibitors. This partnership was pivotal for both companies.
- 2014: The FDA approved Viekira Pak, a therapy for Hepatitis C, which marked a significant achievement for Enanta’s collaboration with AbbVie.
Financial Performance
As of the fiscal year ended September 30, 2022, Enanta reported total revenue of approximately $71.5 million, driven largely by royalties from AbbVie’s sales of Viekira Pak.
| Year | Total Revenue (in millions) | Net Income (in millions) | Research & Development Expenses (in millions) |
|---|---|---|---|
| 2019 | $45.2 | $17.5 | $30.4 |
| 2020 | $56.3 | $23.5 | $31.6 |
| 2021 | $49.8 | $24.1 | $43.5 |
| 2022 | $71.5 | $29.8 | $44.1 |
Research and Development Focus
Enanta Pharmaceuticals has concentrated efforts on several key areas, including:
- Hepatitis C Virus (HCV)
- Respiratory Syncytial Virus (RSV)
- Novel coronavirus (COVID-19) treatments
Recent Innovations and Collaborations
In 2023, Enanta entered into a collaboration with a global pharmaceutical company to develop an oral antiviral therapy for RSV, showcasing the ongoing commitment to addressing unmet medical needs.
Market Position and Stock Performance
As of October 2023, Enanta's stock (NASDAQ: ENTA) was trading at approximately $20.50 per share. The company’s market capitalization stood at around $490 million.
Enanta continues to explore strategic partnerships to expand its pipeline and enhance its market presence.
A Who Owns Enanta Pharmaceuticals, Inc. (ENTA)
Corporate Ownership Structure
As of the latest available data, Enanta Pharmaceuticals, Inc. (ENTA) has a diverse ownership structure. Key stakeholders include institutional investors, individual shareholders, and company insiders.
| Ownership Type | Percentage Owned |
|---|---|
| Institutional Investors | 91.04% |
| Insider Ownership | 4.83% |
| Individual Retail Investors | 4.13% |
Major Institutional Shareholders
The following table lists the major institutional shareholders of Enanta Pharmaceuticals, along with their respective ownership percentages as of the most recent filings.
| Institution | Shares Owned | Percentage of Total Shares |
|---|---|---|
| The Vanguard Group, Inc. | 1,700,000 | 10.5% |
| BlackRock, Inc. | 1,500,000 | 9.3% |
| State Street Corporation | 1,200,000 | 7.5% |
| Dimensional Fund Advisors LP | 800,000 | 5.0% |
| Invesco Ltd. | 600,000 | 3.8% |
Insider Ownership Details
Insider ownership plays a crucial role in the governance of Enanta Pharmaceuticals. Below is a summary of key insiders and their holdings:
| Name | Position | Shares Owned | Percentage of Total Shares |
|---|---|---|---|
| Jay R. Luly | President and CEO | 450,000 | 2.8% |
| Jeffrey L. Hatfield | COO | 200,000 | 1.3% |
| Catherine C. H. D'Amato | Director | 150,000 | 0.9% |
Recent Stock Performance and Market Capitalization
As of the latest available data in October 2023, Enanta Pharmaceuticals’ stock performance has exhibited notable trends, reflected in the following financial metrics:
| Date | Stock Price (USD) | Market Capitalization (USD) |
|---|---|---|
| October 1, 2023 | 24.50 | 550 million |
| October 15, 2023 | 26.00 | 570 million |
| October 30, 2023 | 25.00 | 560 million |
Summary of Ownership Trends
Over recent years, Enanta Pharmaceuticals has experienced changes in its ownership distribution, with institutional investors gaining a larger share. This trend can be illustrated as follows:
| Year | Institutional Ownership (%) | Insider Ownership (%) | Individual Ownership (%) |
|---|---|---|---|
| 2020 | 85.5% | 5.5% | 9.0% |
| 2021 | 88.0% | 5.0% | 7.0% |
| 2022 | 90.0% | 4.0% | 6.0% |
| 2023 | 91.0% | 4.8% | 4.1% |
Conclusion on Stakeholder Dynamics
The ownership dynamics of Enanta Pharmaceuticals, Inc. reflect a strong institutional presence and a committed team of insiders. The trends indicate a growing influence of institutional investors while maintaining a solid foundation with insider stakeholders.
Enanta Pharmaceuticals, Inc. (ENTA) Mission Statement
Company Overview
Enanta Pharmaceuticals, Inc. (ENTA) is a biotechnology company focused on developing innovative viral therapeutics, with a particular emphasis on hepatitis C and other infectious diseases. As of October 2023, ENTA's market capitalization stands at approximately $570 million.
Core Mission Statement
The mission of Enanta Pharmaceuticals is to discover and develop small molecule drugs for viral infections, aiming to improve the lives of patients worldwide. The company emphasizes its commitment to scientific excellence, innovation, and the pursuit of transformative therapies.
Strategic Objectives
- To advance a robust pipeline of antiviral therapeutics.
- To collaborate with industry leaders and research institutions.
- To maintain financial discipline while reinvesting in R&D initiatives.
- To uphold a patient-centric approach in drug development practices.
Financial Highlights
| Financial Metric | Value |
|---|---|
| Total Revenue (2022) | $28.6 million |
| Net Income (2022) | $10.1 million |
| Cash and Cash Equivalents (as of Q3 2023) | $171.5 million |
| R&D Expenses (2022) | $18.4 million |
| Market Capitalization (as of October 2023) | $570 million |
Research and Development Focus
Enanta Pharmaceuticals prioritizes the development of medications targeting viral infections with significant unmet medical needs. The company's pipeline is strategically aligned with the following objectives:
- To enhance treatment efficacy for hepatitis B and C.
- To explore novel compounds against emerging viral threats.
- To innovate within the field of antiviral therapeutics.
Values and Principles
The core values guiding Enanta's operations include:
- Integrity: Conducting business in an ethical manner.
- Innovation: Fostering creativity in drug discovery.
- Collaboration: Building partnerships to enhance R&D efforts.
- Excellence: Delivering high-quality therapeutic candidates.
Partnerships and Collaborations
Enanta actively engages in strategic partnerships to amplify its research efforts. Notable collaborations include:
- Collaboration with AbbVie for the development of glecaprevir/pibrentasvir, a treatment for hepatitis C.
- Partnerships with academic institutions for exploratory research.
Future Directions
The company aims to expand its research portfolio and enhance its pipeline through:
- Investment in cutting-edge technologies for drug development.
- Focus on the commercialization of its antiviral products.
- Exploration of new therapeutic areas.
| Future Initiatives | Expected Outcomes |
|---|---|
| Expansion of pipeline into respiratory viruses | Address additional unmet needs in viral therapeutics |
| Increased R&D expenditures | Foster innovation and shorten development timelines |
| Strengthening partnerships | Leverage shared resources and expertise |
How Enanta Pharmaceuticals, Inc. (ENTA) Works
Overview of Enanta Pharmaceuticals
Enanta Pharmaceuticals, Inc. (ENTA) is a clinical-stage biotechnology company based in Watertown, Massachusetts. The company focuses on developing small molecule drugs for viral infections and liver diseases. As of the end of 2022, Enanta had multiple compounds in clinical trials, particularly targeting hepatitis B and the coronavirus.
Business Model
Enanta's business model revolves around research and development (R&D) of novel therapeutics. The company primarily relies on a combination of internal drug discovery programs and partnerships with larger pharmaceutical companies to advance its pipeline. Enanta's collaborations often provide funding and resources to expedite development.
Financial Performance
For the fiscal year ending September 30, 2022, Enanta reported:
- Total revenue: $36.6 million
- Net loss: $49.7 million
- Research and development expenses: $31.9 million
- General and administrative expenses: $19.6 million
Clinical Pipeline
Enanta Pharmaceuticals has a robust pipeline focused on:
- Hepatitis B Virus (HBV) therapies
- SARS-CoV-2 (COVID-19) treatments
- Other viral infections and liver diseases
| Product | Indication | Phase | Collaboration |
|---|---|---|---|
| EBR-104 | Hepatitis B | Phase 2 | AbbVie |
| R552 | COVID-19 | Phase 1 | No collaboration |
| ENB-001 | Hepatitis C | Preclinical | No collaboration |
Research Collaborations
Enanta has established partnerships with major pharmaceutical companies to enhance its R&D capabilities:
- AbbVie
- Hoffmann-La Roche
- Merck & Co.
Stock Performance
As of October 2023, Enanta's stock (ENTA) is trading at approximately $20.25 per share. The stock has experienced volatility over the past year, with a 52-week high of $42.70 and a low of $13.54.
Intellectual Property
Enanta has a strong intellectual property portfolio, comprising over 100 patents related to its drug candidates and technologies.
Market Strategy
The company aims to leverage its expertise in drug discovery and development to deliver innovative therapies that address unmet medical needs in viral infections and liver diseases.
Future Outlook
Enanta's focus remains on advancing its clinical pipeline, with expectations of potential partnerships and collaborations to support future growth. The company anticipates continued investment in R&D to drive innovation and expansion of its therapeutic offerings.
How Enanta Pharmaceuticals, Inc. (ENTA) Makes Money
Revenue Streams
Enanta Pharmaceuticals, Inc. primarily generates revenue through various channels such as collaborations, royalties, and product sales.
- Collaboration Agreements
- Royalties from Licensed Products
- Product Sales of Proprietary Drugs
Collaboration Agreements
Enanta has established significant partnerships with major pharmaceutical companies. Notably, its collaboration with AbbVie focuses on the development of treatments for hepatitis C, contributing substantially to its revenues.
| Partner | Year Initiated | Initial Payment (in millions) | Potential Milestones (in millions) |
|---|---|---|---|
| AbbVie | 2012 | 25 | 375 |
| Other Collaborators | N/A | 10 | 150 |
Royalties from Licensed Products
Enanta earns royalties from the sales of direct products resulting from its research and development. The company primarily benefits from the sales of its partnered products in the market.
| Product | Royalty Percentage | 2022 Royalties (in millions) |
|---|---|---|
| AbbVie's Mavyret | 1% - 2% | 15.4 |
| Other Products | 3% - 5% | 7.2 |
Product Sales
Enanta has developed its proprietary drug candidates which can be sold upon successful market entry. The company's focus on infectious diseases provides a lucrative avenue for future revenues.
- Pipeline Products:
- ENB-003: Advanced Phase II
- ENB-004: Preclinical Stage
Financial Performance
As of September 2023, Enanta's financial statements reflect sustained growth.
| Metric | 2021 | 2022 | 2023 (Q3) |
|---|---|---|---|
| Total Revenue (in millions) | 35.5 | 50.2 | 38.7 |
| Net Income (in millions) | 10.2 | 18.4 | 12.9 |
| Cash and Cash Equivalents (in millions) | 100.0 | 135.4 | 120.3 |
Market Potential
The global market for antiviral drugs has reached approximately $60 billion in 2022, with expectations to grow due to ongoing research and development in infectious diseases.
| Market Segment | 2022 Market Size (in billions) | Projected Growth Rate (CAGR 2023-2030) |
|---|---|---|
| Antiviral Drugs | 60 | 7.5% |
| Hepatitis C Treatments | 10 | 5.6% |
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