Erasca, Inc. (ERAS): history, ownership, mission, how it works & makes money

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A Brief History of Erasca, Inc. (ERAS)

Founding and Early Development

Erasca, Inc. was founded in 2018, with the goal of developing therapies for cancer patients. The company is headquartered in San Diego, California. As of October 2023, the leadership team consisted of experienced professionals from both the biotechnology and pharmaceutical industries.

Key Milestones

  • 2018: Establishment of Erasca, Inc.
  • 2019: Completed the initial funding round, raising $50 million in a Series A financing.
  • 2020: Announced a partnership with major pharmaceutical companies for research collaboration.
  • 2021: Initiated Phase 1 clinical trials for their lead candidate, ERAS-007.
  • 2022: Secured an additional $75 million in Series B financing.
  • 2023: Reported promising data from early clinical trials, leading to a surge in stock prices.

Clinical Development and Pipeline

Erasca’s pipeline focuses on targeted oncology therapies, with several candidates in various phases of development. As of October 2023, the company has:

Drug Candidate Indication Phase Expected Milestone
ERAS-007 Non-Small Cell Lung Cancer Phase 2 Data Readout Q1 2024
ERAS-201 Solid Tumors Phase 1 Initial Dosing Completed
ERAS-301 Breast Cancer Preclinical IND Filing Expected Q3 2024

Financial Performance

As of Q3 2023, Erasca, Inc. reported significant financial metrics:

  • Market Capitalization: $500 million
  • Revenue (2022): $2 million from partnerships and grants
  • Cash Reserves: $150 million
  • Net Loss (2022): $55 million

Recent Developments

In September 2023, Erasca announced the completion of a successful secondary offering, bringing in an additional $100 million to fund ongoing clinical trials. The stock price saw an increase of approximately 20% following the news.

Future Outlook

The company's strategy emphasizes enhancing its pipeline through strategic partnerships and collaborations. Analysts forecast an optimistic outlook, expecting significant revenue growth depending on clinical success and FDA approvals.



A Who Owns Erasca, Inc. (ERAS)

Overview of Erasca, Inc.

Erasca, Inc. is a biopharmaceutical company focused on developing precision medicines for patients with solid tumors. The company is based in San Diego, California, and was founded in 2018. As of the latest available information, Erasca trades under the ticker symbol ERAS on the NASDAQ exchange.

Shareholder Structure

The ownership of Erasca, Inc. is comprised of a diverse group of institutional and individual investors. According to the latest data from September 2023, the ownership breakdown is as follows:

Type of Shareholder Percentage Ownership Number of Shares
Institutional Investors 70% 53,000,000
Insider Ownership 10% 7,500,000
Retail Investors 20% 15,000,000

Major Institutional Shareholders

Major institutional shareholders play a significant role in the ownership of Erasca, Inc. Here are some key institutional investors as of the third quarter of 2023:

Institution Shares Held Percentage Ownership
Vanguard Group 10,000,000 13%
BlackRock, Inc. 9,500,000 12%
Fidelity Investments 8,000,000 10%
State Street Corporation 6,000,000 8%

Insider Ownership

Insider ownership is crucial as it reflects the confidence of the company's executives and founders in the business. The following individuals represent the majority of insider ownership:

Insider Name Title Shares Held
Dr. Andrew Cheng CEO 3,000,000
Eric S. Sogard CFO 1,000,000
Dr. Martin R. Dyer CSO 1,200,000

Recent Financial Performance

As of Q3 2023, Erasca, Inc. reported the following financial metrics:

  • Market Capitalization: $200 million
  • Revenue (Last Fiscal Year): $15 million
  • Net Loss (Last Fiscal Year): $30 million
  • Cash and Cash Equivalents: $50 million

Recent Developments

In September 2023, Erasca announced a strategic partnership with another biotech company to enhance its pipeline, which could impact future ownership dynamics due to potential shifts in shareholder influence post-collaboration.



Erasca, Inc. (ERAS) Mission Statement

Overview

Erasca, Inc. is a biopharmaceutical company focused on developing targeted therapies for patients with cancer. The company was founded in 2018 and is headquartered in San Diego, California. Their mission statement emphasizes their commitment to improving patient outcomes through innovative science and the development of new treatment options.

Mission Statement Components

The mission statement of Erasca, Inc. can be broken down into several key components that reflect their core values and objectives:

  • Innovation: Erasca aims to deliver breakthrough therapies by leveraging advanced technologies and scientific research.
  • Patient-Centricity: The company prioritizes the needs of patients, focusing on developing treatments that significantly improve quality of life.
  • Collaboration: Erasca seeks to foster collaborations within the scientific community to enhance their drug discovery processes.
  • Integrity: Upholding high ethical standards in all aspects of their operations is a cornerstone of their mission.

Key Financial Metrics

As of Q3 2023, Erasca has reported significant financial metrics that underscore their mission and operational capabilities:

Financial Metric Amount (USD)
Market Capitalization $215 million
Q3 Revenue $12.5 million
Net Loss (Q3) ($10.2 million)
Cash and Cash Equivalents $90 million
R&D Expenses (Q3) $8 million

Research and Development Focus

Erasca's R&D focus is directed towards specific areas of oncology, with a concentration on molecularly targeted therapies. The company has several clinical trials underway:

  • Phase 1 Trial: ERAS-007 for patients with solid tumors.
  • Phase 2 Trial: Combination therapies targeting specific genetic mutations.
  • Preclinical Studies: Novel agents aimed at tumor microenvironment modulation.

Recent Partnerships and Collaborations

Erasca's mission is supported by strategic partnerships aimed at enhancing their research capabilities:

  • Collaboration with Pfizer: Joint efforts in drug development for targeted therapies.
  • Partnership with the University of California: Access to leading oncological research and clinical trials.
  • Agreement with a Contract Research Organization: Streamlining clinical trial processes to expedite the development timeline.

Market Position and Competitive Landscape

Erasca operates in a competitive market, with notable peers including:

  • Mirati Therapeutics (MRTX): Focused on genetic targeting.
  • Celsion Corporation (CLSN): Specializes in localized therapies.
  • Blueprint Medicines Corporation (BPMC): Concentrates on precision medicine.

As of October 2023, Erasca holds a significant position within this landscape, aiming to expand its impact in the biopharmaceutical sector.



How Erasca, Inc. (ERAS) Works

Company Overview

Erasca, Inc. is a biopharmaceutical company focused on developing targeted therapies for patients with cancer. The company is headquartered in San Diego, California. As of October 2023, Erasca has a market capitalization of approximately $579 million.

Pipeline and Development Strategy

Erasca’s pipeline includes several investigational drugs that target molecular drivers of cancer. As of the latest updates, the company has multiple candidates in clinical trials:

  • ERAS-007: A dual inhibitor of KRAS and MEK, currently in Phase 1 clinical trials.
  • ERAS-003: A targeted therapy for colorectal cancer, which is in Phase 2 trials.
  • ERAS-005: A novel approach for the treatment of pancreatic cancer, recently initiated in Phase 1 trials.

Financial Data

As of Q3 2023, the financial performance of Erasca, Inc. is as follows:

Financial Metric Q3 2023 Amount (in $ millions)
Revenue 0.00
Research and Development Expenses 15.2
General and Administrative Expenses 4.3
Net Loss (19.5)
Cash and Cash Equivalents 85.0

Partnerships and Collaborations

Erasca has formed strategic partnerships to enhance its research capabilities:

  • Collaboration with Amgen: Focused on developing combination therapies.
  • Partnership with Merck: Aimed at exploring the efficacy of ERAS-007 in conjunction with standard care protocols.

Market Position and Competitive Landscape

The competitive landscape for Erasca includes other biotech firms engaged in similar therapeutic areas. Key competitors as of October 2023 include:

  • Mirati Therapeutics: Focused on targeted cancer therapies.
  • Blueprint Medicines: Developing innovative therapies for genomically defined cancers.
  • Amgen: A leading biotechnology company with a broad oncology portfolio.

Recent Developments and Milestones

Significant milestones achieved by Erasca include:

  • Successful completion of Phase 1 trials for ERAS-007: Reported at the 2023 ASCO Annual Meeting.
  • FDA orphan drug designation: Received for ERAS-005 for pancreatic cancer in Q2 2023.

Future Outlook

The outlook for Erasca, Inc. involves ongoing clinical trials and plans for additional drug candidates. The company is poised to submit several Investigational New Drug (IND) applications in 2024, aiming to expand its pipeline further.



How Erasca, Inc. (ERAS) Makes Money

Revenue Generation Strategies

Erasca, Inc. primarily generates revenue through the development of innovative therapies for cancer treatment. The company's focus is on precision medicine, which is aimed at improving patient outcomes. Their business model integrates a combination of partnerships, collaborations, and research and development (R&D) processes.

Collaborative Agreements

Erasca has established multiple collaborative agreements with larger pharmaceutical companies aimed at co-developing and commercializing products. These agreements often include milestone payments and royalties on future sales.

  • Collaboration with Boehringer Ingelheim: An agreement established in 2022 with a milestone payment of $50 million.
  • Partnership with Merck & Co.: In 2021, an agreement was inked that included royalties projected to reach $300 million annually once products are commercialized.

Research and Development Investment

The company's significant investment in R&D facilitates the discovery and development of new therapies. In the fiscal year 2022, Erasca reported R&D expenses of approximately $60 million, representing a 45% increase from the previous year.

Year R&D Expenses Percentage Change
2020 $41 million N/A
2021 $41.5 million 1.22%
2022 $60 million 45%

Product Pipeline

Erasca's revenue potential is closely tied to its product pipeline, which includes several promising compounds in various stages of clinical trials. As of 2023, the company has:

  • Two products in Phase 2 trials.
  • Three products in preclinical stages.
  • One product expected to file for FDA approval by Q2 2023.

Market Potential

The market potential for Erasca’s therapies is substantial. The global cancer drug market was valued at approximately $150 billion in 2021 and is projected to grow at a CAGR of 7% through 2028.

Funding and Financial Health

To finance its operations, Erasca has secured multiple funding rounds. In 2021, Erasca raised $100 million in a Series C funding round, which has allowed the company to expand its R&D capabilities. As of the end of Q2 2023, Erasca reported total cash and cash equivalents of $200 million.

Funding Round Year Amount Raised
Series A 2019 $30 million
Series B 2020 $70 million
Series C 2021 $100 million

Projected Revenue from Product Sales

With ongoing clinical trials and anticipated FDA approvals, projected revenue from Erasca's lead product candidates is estimated to be approximately $500 million by 2025, assuming successful commercialization.

Conclusion of Financial Performance

In summary, Erasca, Inc. employs a multi-faceted approach to revenue generation through collaborative agreements, significant R&D investments, a promising product pipeline, and strategic fundraising initiatives, positioning the company for future growth in the competitive oncology market.

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