Graybug Vision, Inc. (GRAY): history, ownership, mission, how it works & makes money

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A Brief History of Graybug Vision, Inc. (GRAY)

Company Formation and Initial Development

Graybug Vision, Inc. was founded in 2016 by a team of experts in ophthalmology and drug delivery systems. The company focuses on developing innovative treatments for eye diseases, primarily targeting retinal diseases, such as age-related macular degeneration (AMD) and diabetic retinopathy.

Key Milestones

Since its inception, Graybug Vision has achieved several key milestones:

  • 2017: Completion of preclinical studies for its lead product candidate, GB-102.
  • 2018: Secured $10 million in Series A funding to advance product development.
  • 2020: Initiated Phase 1 clinical trials for GB-102.
  • 2021: Announced positive results from Phase 1 trials, demonstrating safety and tolerability.
  • 2022: Expanded pipeline with the introduction of GB-401 for sustained release treatment of glaucoma.

Financial Performance

As of December 2022, Graybug Vision reported the following financial data:

Year Revenue (USD) Net Income (Loss) (USD) Total Assets (USD) Cash and Cash Equivalents (USD)
2020 $0 ($8.1 million) $10.5 million $9.3 million
2021 $0 ($7.4 million) $15.2 million $13.8 million
2022 $0 ($6.9 million) $20.1 million $18.5 million

Funding and Investment

Graybug Vision has successfully attracted several rounds of investment to fuel its development. Notable funding rounds include:

  • 2018: Series A funding of $10 million.
  • 2020: $25 million in Series B funding led by institutional investors.
  • 2021: Additional funding of $15 million to support clinical trials.

Clinical Trials and Product Development

As of 2023, Graybug Vision was conducting multiple clinical trials:

  • GB-102: Phase 2 clinical trial expected to finalize results in mid-2023.
  • GB-401: Phase 1 trial initiated in late 2022, focusing on safety and dosing.

Market Potential and Competitors

The global market for retinal treatments is projected to reach approximately $40 billion by 2026. Graybug Vision competes with established pharmaceutical companies such as:

  • Novartis AG
  • Regeneron Pharmaceuticals, Inc.
  • Roche Holding AG

Recent Developments

By October 2023, the following recent developments were noted:

  • Partnership with a major biotech firm to enhance drug delivery systems.
  • Presentation of clinical data at the Annual Retina Society Conference in September 2023.


A Who Owns Graybug Vision, Inc. (GRAY)

Company Overview

Graybug Vision, Inc. (NASDAQ: GRAY) is a clinical-stage biopharmaceutical company focused on developing transformative medicines for patients with ocular diseases. The company's innovative drug delivery platform aims to address significant unmet needs in ophthalmology.

Shareholder Structure

As of October 2023, the percentage ownership of major shareholders is as follows:

Shareholder Ownership Percentage Type of Ownership
Institutional Investors 78.5% Institutional
Insiders 10.2% Management and Board Members
Retail Investors 11.3% Individual Investors

Major Institutional Investors

Key institutional investors include:

Investor Name Investment Amount (in USD) Ownership Percentage
BlackRock, Inc. 5.2 million 16.4%
The Vanguard Group, Inc. 4.8 million 14.9%
State Street Corporation 3.5 million 10.9%
Wellington Management Company, LLP 3.1 million 9.7%

Insider Ownership

Insider ownership is significant, with the following details:

Name Position Shares Owned
Andreas J. W. B. H. H. Weiler CEO 300,000
Rebecca L. W. Scripps CFO 150,000
James R. Dukart Board Member 100,000

Recent Financial Performance

Graybug Vision, Inc. reported the following financial figures for the year ending September 2023:

Metric Amount (in USD)
Total Revenue 2.5 million
Net Loss (20.4 million)
Total Assets 30 million
Total Liabilities 15 million

Market Capitalization

As of October 2023, the market capitalization of Graybug Vision, Inc. is approximately:

Market Cap (in USD) Stock Price (USD) Outstanding Shares
100 million 5.00 20 million

Recent Stock Performance

The stock performance of Graybug Vision, Inc. over the past year is summarized as follows:

Metric Value
52-Week High (USD) 7.50
52-Week Low (USD) 3.00
Year-to-Date Return -15%


Graybug Vision, Inc. (GRAY) Mission Statement

Corporate Overview

Graybug Vision, Inc. (NASDAQ: GRAY), a clinical-stage biopharmaceutical company, focuses on developing innovative therapies for ocular diseases. The company's lead product candidates aim to provide sustained delivery of medications for diseases such as age-related macular degeneration (AMD) and glaucoma.

Mission Statement

The mission of Graybug Vision, Inc. is to enhance the lives of patients with serious ocular diseases through innovative therapeutic solutions. The company is committed to advancing the treatment landscape by utilizing its proprietary drug delivery technologies.

Core Values

  • Innovation: Continuously seeking novel approaches to ocular therapy.
  • Patient-Centric: Prioritizing the needs and experiences of patients.
  • Integrity: Upholding ethical standards in all business practices.
  • Collaboration: Partnering with healthcare professionals and stakeholders.

Financial Overview

As of Q3 2023, Graybug Vision, Inc. reported the following financial figures:

Financial Metric Amount (USD)
Revenue $0
Net Loss ($7.6 million)
Cash and Cash Equivalents $18.2 million
Total Assets $23.5 million
Total Liabilities $5.3 million
Market Capitalization $35.7 million

Strategic Goals

  • Develop and commercialize sustained-release therapies for ocular diseases.
  • Advance clinical trials for lead candidates, GB-102 and GB-201.
  • Expand intellectual property portfolio related to drug delivery systems.
  • Establish partnerships with leading pharmaceutical companies.

Key Product Candidates

Product Candidate Indication Development Stage
GB-102 Wet AMD Phase 2
GB-201 Glaucoma Phase 1
GB-301 Dry AMD Preclinical

Clinical Development

Graybug's clinical development strategy focuses on leveraging its proprietary delivery technology to achieve sustained therapeutic levels over extended periods. The company has completed multiple clinical trials, investigating dosing regimens and patient responses.

Vision for the Future

The long-term vision of Graybug Vision is to become a leader in ocular therapeutics by offering transformative and efficient treatment options to patients, ultimately improving patient outcomes and quality of life.



How Graybug Vision, Inc. (GRAY) Works

Company Overview

Graybug Vision, Inc. is a clinical-stage biotechnology company focused on developing innovative treatments for serious eye diseases. The company specializes in drug delivery systems for ophthalmic applications, particularly targeting chronic retinal diseases.

Business Model

Graybug's business model is centered around:

  • Innovative drug delivery technologies
  • Partnerships with research institutions and pharmaceutical companies
  • Revenue generation through licensing agreements

Key Products and Technologies

The primary products in Graybug Vision's pipeline include:

  • GB-102: A novel treatment for wet age-related macular degeneration (AMD)
  • GB-401: A sustained-release therapy for diabetic retinopathy

Financial Performance

As of Q3 2023, Graybug Vision, Inc. reported the following financial data:

Financial Metric Value (USD)
Total Revenue 0
Net Loss (12.5 million)
Assets 50 million
Cash and Cash Equivalents 30 million
Market Capitalization 85 million

Research and Development

Graybug Vision allocates a significant portion of its resources to research and development. In 2022, R&D expenses were reported at:

Year R&D Expenses (USD)
2020 5 million
2021 8 million
2022 10 million

Clinical Trials

The company is actively conducting clinical trials for its products. Key trial phases include:

  • Phase 1 for GB-102 initiated in 2022
  • Phase 2 for GB-401 expected to start in late 2023

Market Strategy

Graybug's market strategy focuses on:

  • Identifying unmet needs in ocular therapies
  • Engaging with healthcare professionals for product adoption
  • Building collaborations with major pharmaceutical companies

Stock Information

As of October 2023, the stock performance of Graybug Vision was as follows:

Metric Value
Current Share Price 3.50
52-Week High 6.00
52-Week Low 2.00
Volume (Average) 150,000 shares

Collaborations and Partnerships

Graybug Vision has established several partnerships to enhance its research capabilities:

  • Collaboration with major universities for research on retinal diseases
  • Partnerships with biotech firms for drug development


How Graybug Vision, Inc. (GRAY) Makes Money

Overview of Revenue Streams

Graybug Vision, Inc. primarily generates revenue through the development and commercialization of innovative treatment options for retinal diseases. Their focus lies in sustained-release therapeutics that target diseases such as wet age-related macular degeneration (AMD) and diabetic retinopathy.

Product Development

Graybug's revenue generation is significantly influenced by their product pipeline. As of October 2023, Graybug is advancing its lead product candidate, GB-102, which is designed for the treatment of wet AMD. The projected market size for wet AMD treatments is estimated to reach $10 billion by 2025.

Partnerships and Collaborations

Collaborative agreements are vital for Graybug’s business model. In 2022, the company entered a partnership with a leading pharmaceutical firm, generating an upfront payment of $5 million and potential milestone payments up to $75 million based on regulatory approvals.

Clinical Trials and Funding

Funding from public and private sources has been crucial. For instance, Graybug Vision raised approximately $30 million in a Series B financing round in 2021, which was utilized for clinical trials and product development.

Market Strategies

Graybug employs various market strategies to enhance its revenue potential. The total addressable market (TAM) for their primary candidates is estimated at $30 billion, with projected annual growth rates of approximately 5-7% for retinal disease therapeutics over the next decade.

Revenue Stream Projected Value Notes
Partnership Agreements $5 million - $75 million Based on milestone achievements
Wet AMD Market $10 billion by 2025 Significant growth potential
Series B Funding $30 million For clinical trials, 2021
Total Addressable Market $30 billion For retinal disease therapeutics

Commercialization Plans

Once a product receives regulatory approval, Graybug plans to commercialize through direct sales and potential partnerships with larger pharmaceutical companies, which could significantly elevate revenue streams.

Financial Performance

As of the latest reporting period, Graybug Vision reported total assets of $45 million and liabilities of $15 million, leading to a positive equity position that supports future growth.

Projected Revenue Growth

Financial analysts forecast that with successful product launches, Graybug could see revenue growth reaching upwards of $100 million within five years post-commercialization.

Investment and Valuation

As of the latest funding round in 2023, Graybug Vision, Inc. holds a market valuation of approximately $250 million, reflecting strong investor confidence in their pipeline and business model.

Regulatory Milestones

Achieving key regulatory milestones is essential for Graybug's revenue generation. The company expects to file for FDA approval for GB-102 by late 2024, which could trigger substantial milestone payments from collaboration partners.

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