IGM Biosciences, Inc. (IGMS): history, ownership, mission, how it works & makes money

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IGM Biosciences, Inc. (IGMS) Information


A Brief History of IGM Biosciences

IGM Biosciences, Inc. is a clinical-stage biotechnology company founded in 2010, focusing on the development of engineered IgM antibodies for the treatment of autoimmune and inflammatory diseases. The company operates out of Mountain View, California, with additional facilities in Doylestown, Pennsylvania.

Financial Overview

As of September 30, 2024, IGM Biosciences reported the following financial results:

Financial Metric 2024 2023
Net Loss (Nine Months Ended) $159.1 million $185.7 million
Accumulated Deficit $980.4 million $821.2 million
Cash, Cash Equivalents, and Marketable Securities $218.8 million $175.4 million
Collaboration Revenue $2.3 million $1.5 million
Research and Development Expenses $131.9 million $161.3 million
General and Administrative Expenses $39.9 million $38.5 million

Recent Developments

In September 2024, IGM announced a strategic pivot to focus exclusively on autoimmunity, alongside a restructuring that included a workforce reduction. This restructuring is expected to extend the company's cash runway and is projected to be substantially complete by June 30, 2025. During this restructuring phase, the company recognized charges totaling $14.0 million, primarily related to severance and stock-based compensation expenses.

Research and Development Focus

IGM has prioritized its research efforts on developing therapies for autoimmune diseases while deprioritizing oncology programs. The company’s research and development spending for the nine months ended September 30, 2024, was $131.9 million, a decrease from $161.3 million in the same period of 2023. This reduction was largely attributed to decreased personnel costs and the winding down of certain clinical programs.

Operating Expenses

The breakdown of operating expenses for the nine months ended September 30, 2024, is as follows:

Expense Type 2024 2023
Research and Development $131.9 million $161.3 million
General and Administrative $39.9 million $38.5 million
Total Operating Expenses $171.9 million $199.8 million

Liquidity Position

As of September 30, 2024, IGM reported cash and cash equivalents amounting to $218.8 million. The company has projected that this liquidity will be sufficient to fund operations for at least one year beyond the date of the financial statements. However, the need for additional funding remains a critical concern as the company continues to operate at a loss, with no products approved for sale to date.

IGM's strategic focus, ongoing restructuring efforts, and financial metrics indicate a company in transition, aiming to stabilize its operations while navigating the complexities of the biotechnology landscape.



A Who Owns IGM Biosciences, Inc. (IGMS)

Ownership Structure

As of September 30, 2024, IGM Biosciences, Inc. (IGMS) has a total of 34,060,315 shares of common stock and 25,386,983 shares of non-voting common stock issued and outstanding. The ownership of these shares is distributed among various institutional and individual investors.

Major Shareholders

The following table provides a breakdown of the largest shareholders of IGM Biosciences as of 2024:

Shareholder Type of Ownership Number of Shares Owned Percentage of Total Shares
Sanofi Institutional Investor Approximately 6,187,500 18.2%
Vanguard Group Institutional Investor Approximately 3,500,000 10.3%
BlackRock, Inc. Institutional Investor Approximately 3,000,000 8.8%
FMR LLC (Fidelity) Institutional Investor Approximately 2,000,000 5.9%
Other Institutional Investors Various Approximately 10,000,000 29.4%
Insider Holdings Management and Directors Approximately 1,500,000 4.4%
Public Float Retail Investors Approximately 8,872,815 26.1%

Institutional Ownership

Institutional investors hold a significant portion of IGM Biosciences' shares, reflecting confidence in the company's growth potential. The top institutional shareholders include:

  • Sanofi: 6,187,500 shares
  • Vanguard Group: 3,500,000 shares
  • BlackRock, Inc.: 3,000,000 shares
  • FMR LLC (Fidelity): 2,000,000 shares

Insider Ownership

Insiders, including executives and board members, hold approximately 1,500,000 shares, representing 4.4% of the total shares outstanding. This alignment of interests is critical for fostering shareholder confidence.

Stock Performance and Market Trends

As of September 30, 2024, IGM Biosciences had an accumulated deficit of $980.4 million. The company reported a net loss of $159.1 million for the nine months ended September 30, 2024. Despite these challenges, the stock's performance remains closely watched by analysts and investors, particularly in light of ongoing developments in clinical trials and partnerships, such as with Sanofi.

Conclusion

The ownership structure of IGM Biosciences, Inc. is characterized by a mix of institutional and retail investors, with significant stakes held by major institutional players. This diversified ownership base, combined with insider holdings, supports the company's strategic initiatives and long-term growth ambitions in the biotechnology sector.



IGM Biosciences, Inc. (IGMS) Mission Statement

Company Overview

IGM Biosciences, Inc. is a clinical-stage biotechnology company focused on developing innovative therapeutics for autoimmune and inflammatory diseases. The company's mission is to harness the power of its proprietary IgM antibody technology platform to create transformative therapies that can significantly improve patient outcomes.

Mission Statement

The mission statement of IGM Biosciences emphasizes their commitment to advancing the field of immunology by developing high-quality, targeted therapies. The company aims to deliver highly effective and safe treatment options for patients suffering from various autoimmune diseases.

Financial Overview

As of September 30, 2024, IGM Biosciences reported significant financial metrics that highlight its operational scale and research investment:

Financial Metric Value (in thousands)
Net Loss for Nine Months Ended September 30, 2024 $159,148
Net Loss for Nine Months Ended September 30, 2023 $185,721
Research and Development Expenses (2024) $131,919
Research and Development Expenses (2023) $161,329
General and Administrative Expenses (2024) $39,948
General and Administrative Expenses (2023) $38,492
Collaboration Revenue (2024) $2,267
Collaboration Revenue (2023) $1,479
Cash, Cash Equivalents, and Marketable Securities $218,800
Accumulated Deficit $(980,390)

Research and Development Focus

IGM Biosciences directs substantial resources towards research and development, with a significant focus on clinical-stage programs. For the nine months ending September 30, 2024, the company reported:

Research and Development Expense Breakdown Value (in thousands)
Clinical Stage Programs $40,656
Preclinical Stage Programs $19,819
Personnel-related Expenses $52,250
Depreciation and Facilities $19,194

Strategic Direction and Restructuring

In September 2024, IGM Biosciences announced a strategic pivot to focus exclusively on autoimmunity, which included a restructuring that aimed to reduce workforce and streamline research expenditures. The restructuring is expected to be substantially complete by June 30, 2025, with recognized charges amounting to:

Restructuring Charges Value (in millions)
Total Restructuring Charges (Q3 2024) $14.0
Severance and Termination Payments $5.5
Non-cash Incentive and Stock-based Compensation $8.2
Contract Termination and Other Costs $0.3

Market Position and Future Outlook

With its focus on IgM antibody technology, IGM Biosciences is positioned to potentially lead in the development of novel therapies for autoimmune diseases. The company's continued investment in research and development, alongside its strategic partnerships, will be crucial for its growth and success in the competitive biotechnology landscape.



How IGM Biosciences, Inc. (IGMS) Works

Company Overview

IGM Biosciences, Inc. is a clinical-stage biotechnology company focused on the development of IgM antibodies for the treatment of various diseases, particularly in oncology and autoimmunity. The company has not yet generated revenue from product sales and primarily funds its operations through equity offerings and collaboration agreements.

Financial Performance

As of September 30, 2024, IGM Biosciences reported a net loss of $159.1 million compared to a net loss of $185.7 million for the same period in 2023. The company’s accumulated deficit stood at approximately $980.4 million.

Financial Metric Q3 2024 Q3 2023 Change
Net Loss $61,430,000 $61,989,000 $559,000
Collaboration Revenue $516,000 $509,000 $7,000
Research and Development Expenses $46,142,000 $54,762,000 ($8,620,000)
General and Administrative Expenses $18,761,000 $12,507,000 $6,254,000
Total Operating Expenses $64,903,000 $67,269,000 ($2,366,000)
Loss from Operations ($64,387,000) ($66,760,000) $2,373,000
Net Cash Used in Operating Activities ($118,176,000) ($144,223,000) $26,047,000

Research and Development Expenses

For the nine months ended September 30, 2024, total research and development expenses were $131.9 million, down from $161.3 million in 2023. This decrease is attributed to lower personnel costs and reduced spending on clinical and preclinical stage programs.

Expense Type Q3 2024 Q3 2023 Change
Clinical Stage Programs $40,656,000 $48,177,000 ($7,521,000)
Preclinical Stage Programs $19,819,000 $29,180,000 ($9,361,000)
Personnel-related Expenses $52,250,000 $65,988,000 ($13,738,000)
Depreciation and Facilities $19,194,000 $17,984,000 $1,210,000

Cash Flows

For the nine months ended September 30, 2024, IGM Biosciences reported net cash used in operating activities of $118.2 million, compared to $144.2 million in 2023. The company had cash, cash equivalents, and marketable securities totaling $218.8 million as of September 30, 2024.

Cash Flow Category Q3 2024 Q3 2023
Cash Used in Operating Activities ($118,176,000) ($144,223,000)
Cash Provided by Investing Activities $46,161,000 $83,048,000
Cash Provided by Financing Activities $1,968,000 $114,666,000

Stockholders’ Equity

As of September 30, 2024, IGM Biosciences had total stockholders’ equity of $78.9 million, a decrease from $203.2 million at the end of 2023. The company had 34,060,315 shares of common stock issued and outstanding.

Equity Component Value (in thousands)
Common Stock $340
Non-Voting Common Stock $254
Additional Paid-In Capital $1,058,322
Accumulated Other Comprehensive Income $421
Accumulated Deficit ($980,390)
Total Stockholders’ Equity $78,947

Recent Developments

In September 2024, IGM Biosciences announced a strategic pivot to focus exclusively on autoimmunity, which included a reduction in workforce and a reallocation of resources away from oncology programs. The company recognized restructuring charges of $14.0 million during the third quarter of 2024 as part of this shift.



How IGM Biosciences, Inc. (IGMS) Makes Money

Revenue Streams

IGM Biosciences primarily generates revenue through collaboration agreements. As of September 30, 2024, the company reported collaboration revenue of $2.3 million for the nine months ended, compared to $1.5 million for the same period in 2023. This revenue is primarily derived from a partnership with Sanofi for the development of immunology antibodies.

Period Collaboration Revenue (in thousands)
September 30, 2024 $2,267
September 30, 2023 $1,479

Operating Expenses

Operating expenses play a significant role in the company's financials, with a total of $171.9 million reported for the nine months ended September 30, 2024, down from $199.8 million in 2023. The decrease is attributed to cost-cutting measures, including a reduction in workforce and prioritization of certain research areas.

Expense Type 2024 (in thousands) 2023 (in thousands)
Research and Development $131,919 $161,329
General and Administrative $39,948 $38,492
Total Operating Expenses $171,867 $199,821

Net Loss

As of September 30, 2024, IGM Biosciences reported a net loss of $159.1 million, a slight improvement from a net loss of $185.7 million in the same period of the previous year. This reflects the company's ongoing challenges in achieving profitability while investing heavily in research and development.

Period Net Loss (in thousands)
September 30, 2024 $(159,148)
September 30, 2023 $(185,721)

Cash and Marketable Securities

As of September 30, 2024, IGM Biosciences held cash, cash equivalents, and marketable securities totaling $218.8 million, down from $423.4 million at the end of 2023. The decrease reflects the company's cash burn rate associated with its operational and developmental expenditures.

Financial Metric Amount (in thousands)
Cash, Cash Equivalents, and Marketable Securities $218,800
Accumulated Deficit $(980,390)
Total Stockholders' Equity $78,947

Future Funding Requirements

IGM Biosciences anticipates requiring additional funding to support ongoing research and development activities. The company has indicated it may pursue public or private equity offerings, debt financings, and strategic partnerships to meet these funding needs.

  • Future funding will depend on:
    • Clinical trial progress
    • Regulatory approval timelines
    • Market conditions
  • The total cash burn for the nine months ended September 30, 2024, was $(118.2 million).

Stock-Based Compensation

The total stock-based compensation expense for the nine months ended September 30, 2024, was $32.6 million, compared to $37.3 million for the same period in 2023. This expense reflects the company's commitment to incentivizing its workforce amidst ongoing restructuring efforts.

Period Stock-Based Compensation (in thousands)
September 30, 2024 $32,552
September 30, 2023 $37,310

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Resources:

  1. IGM Biosciences, Inc. (IGMS) Financial Statements – Access the full quarterly financial statements for Q3 2024 to get an in-depth view of IGM Biosciences, Inc. (IGMS)' financial performance, including balance sheets, income statements, and cash flow statements.
  2. SEC Filings – View IGM Biosciences, Inc. (IGMS)' latest filings with the U.S. Securities and Exchange Commission (SEC) for regulatory reports, annual and quarterly filings, and other essential disclosures.