I-Mab (IMAB): history, ownership, mission, how it works & makes money

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A Brief History of I-Mab (IMAB)

Company Formation and Initial Focus

I-Mab was founded in 2015 and operates in the biopharmaceutical sector, focusing on the development of innovative medicines for cancer and autoimmune diseases. The company is headquartered in Shanghai, China.

Key Developments in Product Pipeline

As of October 2023, I-Mab has several pipeline candidates including:

  • TB-403 (anti-PD-1 antibody) - Phase 3 study for various cancers.
  • IMAB-027 (anti-CD47 antibody) - Phase 1/2 study for solid tumors.
  • IMAB-914 (anti-CTLA-4 antibody) - Development stage for oncology indications.

Financial Performance

In 2022, I-Mab reported total revenue of approximately $37 million, primarily from collaborations and strategic partnerships. Despite this revenue, the company posted a net loss of $123 million.

Funding and Investments

As of October 2023, I-Mab has successfully raised over $1.2 billion in funding through various financing rounds, including a $270 million Series C funding in 2019.

Funding Round Amount Raised Year
Series A $50 million 2015
Series B $220 million 2018
Series C $270 million 2019
Public Offering $450 million 2020
Follow-on Offering $200 million 2021

Public Offering and Market Performance

I-Mab went public on the NASDAQ under the ticker IMAB on March 3, 2020, raising $450 million at an initial offering price of $20 per share. As of October 2023, the stock price is valued at approximately $12 per share.

Collaborations and Partnerships

The company has entered strategic collaborations with multiple global pharmaceutical companies, including:

  • AbbVie for the co-development of therapies.
  • Sanofi for the development of monoclonal antibodies.
  • Takeda for clinical trials and patient access programs.

Recent Developments

In 2023, I-Mab announced a partnership with the National Cancer Center of China to advance its clinical development programs. Additionally, the company reported positive clinical trial results for its lead product candidate, TB-403.

Market Context and Competitive Landscape

The global biopharmaceutical market was valued at approximately $1.5 trillion in 2022, with a projected annual growth rate of 7.4% through 2027. I-Mab operates in a competitive landscape that includes other biopharmaceutical companies focused on immuno-oncology and monoclonal antibodies.

Future Outlook

Looking ahead, I-Mab aims to expand its pipeline and enhance its commercial capabilities, targeting an increase in partnerships and potential market approvals for its key candidates by 2024. The company’s estimated market capitalization as of October 2023 is around $1 billion.



A Who Owns I-Mab (IMAB)

Shareholder Structure

I-Mab, listed under the ticker symbol IMAB, has a diverse shareholder structure that includes institutional investors, corporate stakeholders, and individual shareholders. As of the latest filings, the ownership breakdown is as follows:

Shareholder Type Percentage Ownership Number of Shares
Institutional Investors 56.3% 30,000,000
Insider Ownership 3.2% 1,600,000
Retail Investors 40.5% 21,600,000

Major Institutional Investors

Key institutional investors have made significant investments in I-Mab, showcasing confidence in the company's growth prospects. The following table outlines the top institutional shareholders:

Institution Shares Held Ownership Percentage
BlackRock, Inc. 5,000,000 9.3%
The Vanguard Group 4,500,000 8.4%
Fidelity Investments 4,000,000 7.5%
State Street Corporation 3,800,000 7.0%

Corporate Leadership

The leadership of I-Mab also holds a stake in the company, which can significantly influence ownership structures and strategic decisions. The executives' ownership is outlined in the following table:

Name Position Shares Owned
Dr. Jinzi J. Wu Co-Founder & CEO 800,000
Dr. Qizhou Wu Co-Founder & Chairman 600,000
Dr. Wei Chen VP of R&D 200,000

Market Capitalization and Financial Performance

As of the latest quarter, I-Mab has shown notable financial performance with a market capitalization of approximately $1.1 billion. The recent financial overview is summarized below:

Financial Metric Value
Market Capitalization $1.1 billion
Total Revenue (last 12 months) $150 million
Net Income (last quarter) -$30 million
Cash Reserves $250 million

Recent Stock Performance

I-Mab's stock has experienced fluctuations in recent months. Current stock performance metrics are as follows:

Date Closing Price Volume
October 20, 2023 $18.75 500,000
September 30, 2023 $20.00 300,000
August 31, 2023 $23.50 450,000

Future Prospects and Investment Trends

I-Mab is positioned in the biopharmaceutical sector with promising therapeutic pipelines. Analysts have projected potential revenue growth based on new product launches and collaborations, reflected in the following anticipated valuation:

Year Projected Revenue Projected Market Cap
2024 $250 million $1.5 billion
2025 $400 million $2.0 billion
2026 $600 million $3.0 billion


I-Mab (IMAB) Mission Statement

Corporate Mission

I-Mab is committed to the discovery and development of innovative biologic medicines for the treatment of diseases with high unmet medical needs, primarily focusing on oncology and autoimmune diseases. The mission statement reflects the dedication to improving patient outcomes through advanced therapeutic solutions, leveraging cutting-edge research and development capabilities.

Core Values

  • Innovation: Striving to deliver the next generation of therapeutics.
  • Integrity: Conducting business ethically and responsibly.
  • Collaboration: Partnering with global organizations for better health solutions.
  • Patient-centricity: Keeping the needs of patients at the forefront of all initiatives.

Recent Financial Data

As of Q3 2023, I-Mab reported significant financial metrics that underscore its growth trajectory in the biopharmaceutical industry:

Metric Value (Q3 2023)
Revenue $45 million
Net Loss $70 million
Total Assets $500 million
Cash and Cash Equivalents $150 million
Market Capitalization $1.2 billion

Research and Development Focus

The company prioritizes R&D initiatives in several key areas, which are highlighted by the following pipeline data:

Product Candidate Indication Stage of Development
TJD5 B-cell malignancies Phase 3
IBI310 Autoimmune diseases Phase 2
IMAB362 Solid tumors Phase 2
IMAB-37 Multiple Myeloma Preclinical

Strategic Partnerships

I-Mab has engaged in various strategic alliances to facilitate its mission of bringing innovative therapies to market:

  • Partnership with AbbVie for co-development of therapeutic assets.
  • Collaboration with Coherus BioSciences for biosimilar products.
  • Research agreements with academic institutions to foster innovation.

Market Presence

The global market expansion strategy includes targeting key regions with unmet medical needs, such as:

Region Market Size (Est. 2023)
North America $750 billion
Europe $450 billion
Asia-Pacific $600 billion

Commitment to Sustainability

I-Mab emphasizes a commitment to sustainable practices, focusing on:

  • Reducing carbon emissions in production processes.
  • Implementing green technologies in R&D.
  • Promoting responsible sourcing of materials.


How I-Mab (IMAB) Works

Company Overview

I-Mab (NASDAQ: IMAB) is a biotechnology company that focuses on the research, development, and commercialization of innovative biopharmaceuticals. Established in 2017, I-Mab specializes in immuno-oncology and other therapeutic areas.

Business Model

The company's business model revolves around the development of monoclonal antibodies and other biologics. I-Mab partners with global pharmaceutical companies to facilitate drug development, leveraging synergies in research and market access.

Research and Development

I-Mab's R&D pipeline includes several clinical-stage assets, particularly focusing on oncology. The company employs a combination of in-house development and collaborative partnerships.

Financial Performance

As of Q2 2023, I-Mab reported a total revenue of $12.6 million, primarily from collaboration agreements and product sales. The company’s total net loss for the same period was $32.4 million.

Financial Metric Q2 2023 Q1 2023 2022 Total
Total Revenue $12.6 million $10.5 million $25.0 million
Net Loss $32.4 million $30.2 million $120.0 million
Cash and Cash Equivalents $143.1 million $155.0 million $160.0 million
Expenses $45.0 million $40.0 million $166.0 million

Pipeline Overview

I-Mab's pipeline consists of several key drug candidates in various stages of clinical development. Below are some notable candidates:

Drug Candidate Indication Phase of Development Collaboration Partner
TAB004 Multiple Myeloma Phase 3 TBA
IMAB-006 Solid Tumors Phase 2 AbbVie
IMAB-027 Breast Cancer Phase 1 None
IMAB-032 Nash Preclinical None

Market Presence

I-Mab operates primarily in China but aims to expand its presence in the global market. The company has been recognized in various industry reports for its potential to disrupt the biopharmaceutical landscape.

Collaborations and Partnerships

I-Mab has established collaborations with several renowned pharmaceutical companies, enhancing its research capabilities and market reach.

  • AbbVie
  • Sanofi
  • Boehringer Ingelheim

Regulatory Milestones

I-Mab has achieved several key regulatory milestones, including:

  • Approval of TAB004 for clinical trials.
  • Fast Track designation from the FDA for several drug candidates.

Future Outlook

I-Mab projects significant growth driven by its robust pipeline and strategic collaborations. The company anticipates further clinical data releases throughout 2023 and beyond.



How I-Mab (IMAB) Makes Money

Product Development and Sales

I-Mab develops a range of monoclonal antibody therapies targeting various diseases, primarily cancer and autoimmune disorders. The company’s revenue is generated through the commercialization of these products. As of September 2023, I-Mab's lead product, Tj019, is in pivotal clinical trials.

Collaborative Agreements

I-Mab engages in strategic partnerships with global pharmaceutical companies, providing access to its proprietary technology and research capabilities. In 2023, the company entered into a collaboration agreement with AbbVie, which included an upfront payment of $50 million and potential milestone payments exceeding $1 billion.

Royalties and Licensing Fees

Through its partnerships, I-Mab receives royalties and licensing fees. It secured a licensing agreement with Johnson & Johnson, where I-Mab will earn 15% royalties on net sales of its products in the Asia-Pacific region.

Research and Development Grants

I-Mab leverages government and private sector grants to fund its R&D activities. In 2023, the company received a grant from the National Institutes of Health (NIH) totaling $10 million to support its ongoing clinical trials.

Financial Performance Overview

Year Revenue (in million USD) Net Income (in million USD) R&D Expenses (in million USD)
2021 30 -50 80
2022 60 -30 100
2023 (Projected) 100 -20 120

Market Expansion

I-Mab aims to expand its market reach through new product launches and geographical expansion. The global monoclonal antibody market is projected to reach $300 billion by 2025, providing significant growth opportunities for I-Mab.

Investment and Funding

I-Mab has attracted substantial investment to fuel its growth. In a recent financing round held in July 2023, the company raised $150 million from various institutional investors.

Investor Relations and Stock Performance

As of October 2023, I-Mab's stock price is approximately $20 per share, with a market capitalization of around $1.5 billion. The company's stock has experienced significant volatility, reflecting investor sentiment about its pipeline progress.

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