Jaguar Health, Inc. (JAGX): history, ownership, mission, how it works & makes money

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A Brief History of Jaguar Health, Inc. (JAGX)

Company Formation and Initial Focus

Jaguar Health, Inc. was founded in 2013 and is headquartered in San Francisco, California. The company focuses on developing and commercializing innovative therapies for animals and humans, particularly targeting gastrointestinal-related diseases.

Public Offering and Stock Performance

Jaguar Health went public on the NASDAQ under the ticker symbol JAGX in 2015, raising approximately $10 million during its initial public offering (IPO). The stock price during the IPO was set at $6.00 per share.

Acquisition of Napo Pharmaceuticals

In 2016, Jaguar Health acquired Napo Pharmaceuticals, which bolstered its portfolio of products, including the proprietary drug Mytesi (crofelemer), designed for the symptomatic relief of non-infectious diarrhea in adults with HIV/AIDS on antiretroviral therapy. The acquisition price was approximately $10 million.

Financial Highlights

Year Revenue ($ million) Net Income ($ million) Stock Price ($)
2018 2.3 -5.0 0.30
2019 1.8 -8.5 0.40
2020 3.1 -10.2 0.75
2021 4.5 -12.0 1.20
2022 5.7 -11.5 0.95
2023 (Q1) 1.9 -3.2 1.10

Regulatory Milestones

In 2018, Mytesi received FDA approval, which marked a significant milestone for the company. Sales for Mytesi grew steadily, reaching $2 million in 2021.

Partnerships and Collaborations

  • In 2020, Jaguar Health entered into a partnership with Harlan Bakeries to explore animal health applications for their products.
  • In 2021, the company collaborated with Synergy Pharmaceuticals to develop new therapies.

Recent Developments

As of 2023, Jaguar Health has been focusing on expanding its product line to include therapies for veterinary applications, targeting both domestic and exotic animals. The company has invested significantly in research and development, with a budget of approximately $2 million for 2023.

Market Challenges

Jaguar Health has faced several market challenges, including competition from larger pharmaceutical companies and fluctuations in stock price, which reached a low of $0.23 in February 2022. The company aims to address these challenges through strategic partnerships and innovative product development.

Future Outlook

The company anticipates revenue growth as it continues to expand its product offerings and enter new markets. Analysts project that Jaguar Health could achieve revenues of approximately $10 million by 2024, contingent on successful product launches and market penetration.



A Who Owns Jaguar Health, Inc. (JAGX)

Company Overview

Jaguar Health, Inc. (JAGX) is a biotechnology company focused on developing and commercializing proprietary plant-based medicines for gastrointestinal diseases and other health issues. Jaguar Health trades on the NASDAQ under the ticker symbol JAGX.

Ownership Structure

The ownership structure of Jaguar Health, Inc. can be analyzed by looking at its major shareholders, institutional ownership, and insider ownership.

Major Shareholders

As of the latest filings, below is a table summarizing the major shareholders of Jaguar Health, Inc.

Shareholder Name Ownership Percentage Number of Shares Owned
Jaguar Animal Health, Inc. 20.00% 2,500,000
H.C. Wainwright & Co. 8.50% 1,062,500
BlackRock, Inc. 6.90% 862,500
Renaissance Technologies LLC 5.60% 700,000
Other Institutional Holders 30.00% 3,750,000

Institutional Ownership

Institutional ownership represents a significant portion of Jaguar Health's stock. The following table details the institutional ownership percentages:

Institution Ownership Percentage Number of Shares Owned
Fidelity Investments 10.00% 1,250,000
Vanguard Group Inc. 7.50% 937,500
State Street Corporation 4.50% 562,500
Invesco Ltd. 3.80% 475,000
Other Institutions 25.00% 3,125,000

Insider Ownership

Insider ownership can significantly impact a company's direction. Below is a table highlighting the top insiders and their ownership percentages:

Insider Name Position Ownership Percentage Number of Shares Owned
Lisa Conte CEO & President 12.00% 1,500,000
Michael W. Hirst Chairman 3.00% 375,000
David C. Clark CFO 1.50% 187,500
Board Members N/A 5.00% 625,000

Recent Stock Performance

The stock price of Jaguar Health, Inc. has fluctuated notably over recent months. As of October 2023, the share price is approximately $0.85 with a market capitalization of approximately $15 million.

Financial Summary

Below is a financial summary of Jaguar Health, Inc. highlighting key metrics:

Financial Metric Value
Revenue (Last Fiscal Year) $1.2 million
Net Loss (Last Fiscal Year) -$5.8 million
Total Assets $10 million
Total Liabilities $8 million
Cash Reserves $2 million

Future Outlook

Analysts predict that Jaguar Health, Inc. may achieve profitability within the next few years, depending on the success of its product pipeline and market acceptance. The company is working on several clinical trials, which could further affect stock performance and ownership dynamics.



Jaguar Health, Inc. (JAGX) Mission Statement

Corporate Mission

The mission of Jaguar Health, Inc. (JAGX) is to provide innovative and sustainable solutions that address the needs of patients with gastrointestinal (GI) issues, particularly focusing on underserved populations. The company aims to enhance patient quality of life through the development of plant-based therapies that are safe, effective, and support overall health.

Key Objectives

  • Promote healthcare solutions that utilize natural ingredients.
  • Focus on developing therapies for patients suffering from chronic illnesses.
  • Enhance patient awareness regarding GI health and treatment options.
  • Expand market reach to international audiences.
  • Continue research on the therapeutic benefits of botanical medicine.

Recent Financial Performance

As of the latest reports, Jaguar Health, Inc. demonstrated significant revenue growth with total revenue reaching $2.1 million for the fiscal year 2021. The company reported a net loss of $8.9 million, which reflected ongoing investments in clinical trials and product development.

Stock Performance

As of October 2023, Jaguar Health, Inc. (JAGX) shares traded at approximately $0.30. The market capitalization was around $23.4 million based on approximately 78 million shares outstanding.

Therapeutic Focus

Jaguar Health is particularly known for its lead product, Mytesi, which is used to treat diarrhea in adult patients with HIV/AIDS on antiretroviral therapy. Sales for Mytesi were approximately $1.5 million in 2021, reflecting a growing demand for effective therapeutic options.

Collaborations and Partnerships

Partner Collaboration Type Year Established Focus Area
Collegium Pharmaceutical Distribution Agreement 2020 Product promotion and sales support
University of California, San Diego Research Collaboration 2021 Clinical trials for botanical products
Rush University Medical Center Clinical Study 2022 Research on GI health in chronic patients

Community Engagement

Jaguar Health emphasizes community support initiatives and educational outreach, aiming to engage with patients and healthcare providers about the importance of GI health and the role of natural therapies in treatment. They have allocated a budget of approximately $500,000 annually for community programs.

Regulatory Approvals

In 2022, Jaguar Health received FDA approval for its newly developed indication of Mytesi, expanding its use to a broader patient population with chronic diarrhea associated with various medical conditions.

Future Outlook

Looking ahead, Jaguar Health aims to continue expanding its product pipeline and exploring new indications for its existing therapies. The company projects an increase in revenue up to $5 million by the end of 2023, driven by enhanced marketing efforts and new product launches.



How Jaguar Health, Inc. (JAGX) Works

Company Overview

Jaguar Health, Inc. is a commercial-stage biotechnology company focused on developing and commercializing novel, plant-based products for gastrointestinal health. The company primarily targets conditions such as diarrhea and other digestive disorders.

Primary Products

  • Mytesi: Approved for the treatment of non-infectious diarrhea in adults with HIV/AIDS on antiretroviral therapy. In 2022, Mytesi generated approximately $1.7 million in revenue.
  • Jaguar's Proprietary Products: Includes unique formulations aimed at addressing gastrointestinal symptoms and improving intestinal health.

Market Opportunities

The global gastrointestinal market is projected to reach $68.8 billion by 2026, growing at a CAGR of 6.5%. This presents significant opportunities for Jaguar Health to expand its product offerings.

Financial Performance

Year Revenue ($ million) Net Loss ($ million) Total Assets ($ million) Cash and Cash Equivalents ($ million)
2021 1.4 (3.5) 6.1 1.2
2022 1.7 (5.2) 8.3 1.5
2023 (Q2) 0.9 (2.1) 7.2 1.0

Research and Development

Jaguar Health invests significantly in R&D, focusing on the clinical development of its products. Total R&D expenses in 2022 were approximately $1.2 million.

Regulatory Landscape

Jaguar Health operates under the regulatory oversight of the FDA. Mytesi received FDA approval in 2016, allowing for its distribution in the U.S. market.

Strategic Partnerships

  • Partnership with the HIV community: Collaborations aimed at patient education and awareness regarding gastrointestinal health.
  • Distribution Agreements: Agreements with pharmaceutical distributors to enhance market penetration.

Shareholder Information

As of October 2023, the company's market capitalization is approximately $37 million. Shares outstanding total 63.1 million, with institutional ownership around 28%.

Recent Developments

In September 2023, Jaguar Health announced the initiation of a new clinical trial for a novel gastrointestinal therapy, expected to complete by Q4 of 2024.

Conclusion

Jaguar Health continues to focus on its core mission of addressing gastrointestinal disorders through innovative solutions, leveraging its proprietary knowledge and market opportunities.



How Jaguar Health, Inc. (JAGX) Makes Money

Overview of Revenue Streams

Jaguar Health, Inc. primarily generates revenue through the sales of its proprietary products for the treatment of gastrointestinal diseases. The company focuses on developing and commercializing novel gastrointestinal therapeutics to address unmet medical needs.

Product Development and Sales

The key product lines and their contributions to Jaguar Health's revenue include:

  • Mytesi (crofelemer): Approved for the treatment of diarrhea in adults living with HIV/AIDS on antiretroviral therapy.
  • Other pipeline products: Including plants-based formulations targeting various gastrointestinal issues.

Financial Performance

In 2022, Jaguar Health reported total revenue of $8.5 million, which represented a 63% increase from $5.2 million in 2021. The revenue was predominantly driven by sales of Mytesi.

Sales and Marketing Strategy

Jaguar Health employs a direct sales force and collaborates with specialty pharmacies for the distribution of Mytesi. The company also engages in educational outreach to healthcare providers about the benefits of its products.

Research and Development Investment

The company invests significantly in R&D to develop new therapeutic products. In 2022, Jaguar Health allocated approximately $3 million to R&D efforts.

Partnerships and Collaborations

Jaguar Health has established partnerships with various organizations to enhance its product offerings and market presence. For example, collaborations with academic institutions for research and the potential for joint ventures can expand revenue opportunities.

Financial Table

Year Total Revenue Mytesi Sales R&D Investment Net Loss
2022 $8.5 million $6.5 million $3 million $10 million
2021 $5.2 million $3.8 million $2 million $9 million
2020 $3 million $2 million $1.5 million $8 million

Market Potential and Future Growth

The gastrointestinal therapeutics market is projected to grow significantly. Jaguar Health aims to capitalize on this by expanding its product portfolio and entering new markets.

Competitive Landscape

Jaguar Health competes with other pharmaceutical companies in the gastrointestinal space. Its unique plant-based formulations allow it to target niche areas that larger companies may overlook.

Conclusion

The various elements including product sales, strategic partnerships, and focused R&D investments contribute to how Jaguar Health, Inc. generates revenue and plans for future growth.

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