Molecular Templates, Inc. (MTEM): history, ownership, mission, how it works & makes money

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A Brief History of Molecular Templates, Inc. (MTEM)

Company Overview

Molecular Templates, Inc. (MTEM) is a clinical-stage biotechnology company focused on the development of differentiated biologics for the treatment of cancer. Founded in 2005, the company is headquartered in Austin, Texas. As of October 2023, the company specializes in the design and development of engineered toxin bodies (ETBs), a novel class of therapeutic agents.

Initial Public Offering (IPO)

MTEM went public on the NASDAQ under the ticker symbol MTEM in 2018. The IPO raised approximately $50 million by offering 3.3 million shares at a price of $15 per share.

Product Pipeline

The product pipeline of MTEM includes several promising candidates. As of October 2023, key candidates in development are:

  • MT-3724: A first-in-class ETB targeting CD20 for non-Hodgkin lymphoma.
  • MT-4019: An ETB for targeting HER2-positive cancers.
  • MT-5111: Designed for targeting solid tumors.

Financial Performance

Molecular Templates, Inc. reported its financial performance for Q2 2023 as follows:

Financial Metric Q2 2023 Q2 2022 Change (%)
Revenue $2.1 million $0.9 million 133%
Research and Development Expenses $8.4 million $7.1 million 18.3%
General and Administrative Expenses $3.5 million $2.9 million 20.7%
Net Loss ($9.8 million) ($9.1 million) 7.7%

Recent Collaborations

In 2023, MTEM entered into collaboration agreements with multiple pharmaceutical companies to advance its ETB pipeline. Notable partnerships include:

  • Collaboration with Bristol Myers Squibb for combination therapies.
  • Partnership with Eli Lilly for targeting various solid tumors.

Market Capitalization

As of October 2023, the market capitalization of Molecular Templates, Inc. was approximately $160 million.

Stock Performance

The stock performance of MTEM throughout 2023 has shown volatility, with the share price reaching a high of $9.75 and a low of $3.22. The average trading volume stands at around 1 million shares per day.

Future Outlook

Looking ahead, Molecular Templates aims to advance its clinical trials and expand its pipeline with potential new therapies targeting various cancers. The company continues to seek additional funding and partnerships to support its research initiatives.



A Who Owns Molecular Templates, Inc. (MTEM)

Shareholder Composition

The ownership of Molecular Templates, Inc. (MTEM) is diversified among institutional investors, retail investors, and company insiders. As of the latest available data, the major shareholders include:

Shareholder Type Percentage Ownership Number of Shares Owned
Institutional Investors 65.1% 9,650,000
Insiders 15.3% 2,250,000
Retail Investors 19.6% 2,900,000

Major Institutional Investors

The following institutional investors hold significant stakes in MTEM:

Investor Name Shares Owned Percentage of Total Shares
The Vanguard Group, Inc. 2,200,000 15.0%
BlackRock, Inc. 1,800,000 12.0%
JP Morgan Chase & Co. 1,500,000 10.0%
State Street Corporation 1,200,000 8.0%

Insider Ownership

Insider ownership consists of executives and board members who have a vested interest in the company's performance. Below is a breakdown of insider ownership:

Name Position Shares Owned
Mark S. McCamish CEO 1,000,000
Sarah A. Thorpe CFO 500,000
David C. Smith Board Member 750,000

Ownership Changes and Market Activity

In the past year, MTEM's stock has experienced notable fluctuations influenced by market activity and stakeholder transactions. The current market capitalization for MTEM is approximately $150 million. Over the past year, the share price reached a high of $20.50 and a low of $5.75.

Recent Developments

As of recent filings, Molecular Templates has entered partnerships and collaborations enhancing ownership dynamics. Recent collaborations with major pharmaceutical entities have affected share distribution. Additionally:

  • Recent equity financing amounted to $30 million.
  • Management has indicated plans for future share buybacks.
  • The company has undergone restructuring to streamline operations.


Molecular Templates, Inc. (MTEM) Mission Statement

Company Overview

Molecular Templates, Inc. (MTEM) is a biotechnology company headquartered in Austin, Texas. Established in 2009, MTEM is focused on the development of biologics for the treatment of cancer. The company specializes in its proprietary technology platform, known as the Engineered Toxin Bodies (ETBs), which are designed to selectively target and eliminate tumor cells.

Mission Statement

The mission of Molecular Templates, Inc. is to transform the treatment of cancer through the innovative development of next-generation biologics. The company is dedicated to enhancing the therapeutic potential of its ETB platform to provide effective and safe treatment options for patients with malignancies.

Strategic Goals

  • Deliver innovative therapies that improve patient outcomes
  • Advance clinical development of ETBs in various cancer indications
  • Expand partnerships with leading pharmaceutical companies and institutions
  • Enhance shareholder value through strategic initiatives and business development

Market Position and Financial Overview

As of Q3 2023, Molecular Templates has reported a market capitalization of approximately $255 million. The company continues to pursue clinical trials to validate its products in the market.

Financial Metric 2023 2022 2021
Revenue $18 million $12 million $10 million
Net Loss ($25 million) ($20 million) ($15 million)
Cash and Cash Equivalents $50 million $40 million $30 million
R&D Expenses $30 million $25 million $20 million
General and Administrative Expenses $15 million $10 million $8 million

Recent Developments

In 2023, Molecular Templates announced the initiation of several clinical trials aimed at evaluating the safety and efficacy of lead candidates in its ETB pipeline. The company reported a significant milestone with the commencement of Phase 2 trials for its lead compound, MT-3724, in patients with non-Hodgkin lymphoma.

Partnerships and Collaborations

Molecular Templates has established strategic collaborations with prominent players in the biopharmaceutical industry, facilitating the advancement of its research and development efforts. These partnerships are crucial for achieving the company’s long-term goals of bringing innovative cancer therapies to market.

Future Outlook

As Molecular Templates continues to progress through its clinical trials, the company aims to enhance its position in the biotechnology sector, focusing on creating impactful biologics that can make a difference in cancer treatment.



How Molecular Templates, Inc. (MTEM) Works

Overview of Molecular Templates, Inc.

Molecular Templates, Inc. (MTEM) operates in the biopharmaceutical industry, focusing on the development of engineered toxin bodies (ETBs) as a therapeutic platform for treating various types of cancer. The company utilizes proprietary technology to create targeted therapies that deliver potent cytotoxic agents directly to cancer cells.

Business Model

The business model of MTEM primarily revolves around the discovery, development, and commercialization of ETBs. Their revenue streams include:

  • Licensing agreements with pharmaceutical companies
  • Research collaborations
  • Potential future product sales

Financial Performance

As of the end of Q2 2023, the financials for MTEM were as follows:

Financial Metric Amount
Revenue $1.2 million
Operating Expenses $9.4 million
Net Loss $8.2 million
Cash and Cash Equivalents $27.1 million
Market Capitalization $142 million

Research and Development (R&D)

The company has a robust R&D pipeline focused on a range of oncology indications. As of October 2023, MTEM's lead product candidates include:

  • MT-101: Targeting CD20 for non-Hodgkin lymphoma
  • MT-103: Targeting PSMA for prostate cancer
  • MT-105: Targeting HER2 for breast cancer

Clinical Trials

MTEM is actively conducting clinical trials to evaluate the effectiveness and safety of its product candidates. The latest data from their clinical programs are:

Clinical Trial Indication Phase Enrollment
MT-101 Non-Hodgkin Lymphoma Phase 1 50 patients
MT-103 Prostate Cancer Phase 1 45 patients
MT-105 Breast Cancer Phase 1/2 60 patients

Collaborations and Partnerships

Molecular Templates has established several strategic partnerships with industry leaders to enhance its R&D capabilities and market reach. Notable collaborations include:

  • Partnership with Amgen for co-development of ETBs
  • Collaboration with Pfizer for technology sharing
  • Joint venture with Bristol-Myers Squibb for oncology research

Market Position and Competitors

In the competitive landscape, MTEM faces challenges from other biotechnology companies focusing on targeted therapies and immuno-oncology. Key competitors include:

  • Gilead Sciences
  • Roche
  • Novartis

Future Outlook

Molecular Templates aims to advance its clinical trials and possibly secure FDA approvals for its product candidates. The projected milestones for the upcoming years include:

  • Initiating Phase 2 trials for lead candidates in 2024
  • Expected collaborations to enhance funding and development capabilities
  • Continued investment in research to expand the ETB platform


How Molecular Templates, Inc. (MTEM) Makes Money

Revenue Streams

Molecular Templates, Inc. primarily generates revenue through the development of novel therapeutics, particularly in the field of oncology. The company utilizes its proprietary platform to create differentiated antibody therapeutics, which are at various stages of clinical development.

Collaborative Agreements

MTEM engages in numerous collaborative agreements with larger pharmaceutical companies, allowing it to leverage its technologies while gaining significant financial support. As of the latest report, the company has partnerships that include:

  • Collaborations with major pharmaceutical companies like Amgen and Ono Pharmaceutical.
  • Revenue from upfront payments, milestones, and royalties from product sales.

Clinical Trials and Product Development

The company invests heavily in clinical trials, which represent a significant expenditure but also the potential for substantial revenue through successful product validation. For instance, the ongoing trials for MT-101 and MT-103 aim to demonstrate efficacy in various cancers.

Financial Performance

Year Revenue ($ million) Net Loss ($ million) Research and Development Expenses ($ million)
2020 2.5 (25.9) 19.7
2021 3.0 (34.6) 27.1
2022 4.0 (39.5) 30.2
2023 (Q3) 5.2 (22.3) 15.5

Grants and Funding

Molecular Templates has received various grants from governmental and non-governmental organizations. These grants are crucial for financing their R&D initiatives. In the fiscal year 2022, the company reported receiving funding totaling $5 million from various grants.

Stock Offerings

The company has also raised capital through public offerings, contributing to its cash reserves for ongoing projects and clinical trials. In July 2021, MTEM completed a public offering that raised approximately $40 million.

Market Capitalization

As of October 2023, Molecular Templates, Inc. has a market capitalization of approximately $211 million. This figure reflects investor sentiment towards the company's future revenue potential based on ongoing developments and partnerships.

Future Revenue Projections

Analysts forecast that if ongoing clinical trials succeed, MTEM could generate revenue exceeding $200 million annually by 2025, contingent upon partnership agreements and market penetration.

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