NeuBase Therapeutics, Inc. (NBSE) Bundle
A Brief History of NeuBase Therapeutics, Inc. (NBSE)
Foundation and Early Development
Foundation and Early Development
NeuBase Therapeutics was founded in 2018. The company is headquartered in Pittsburgh, Pennsylvania. It is focused on developing gene therapies based on a novel approach that utilizes its proprietary "PATrOL" platform, which stands for "Pharmacologically-Attenuated Targeted RNA Oligonucleotide." This approach is designed to enable targeted modulation of gene expression to treat genetic diseases.
Initial Public Offering (IPO) and Financial Overview
In August 2020, NeuBase executed its initial public offering (IPO) raising approximately $15 million at a price of $5.00 per share. The company was listed on the NASDAQ under the ticker symbol "NBSE." As of the end of Q3 2023, NeuBase's market capitalization was approximately $20 million.
Key Programs and Research Initiatives
NeuBase's primary focus is on its pipeline of therapeutics targeting genetic disorders, such as:
- Huntington's Disease
- Myotonic Dystrophy
- Other neurodegenerative conditions
The company's lead candidate, NT-005, is in preclinical development stages for Huntington's disease, with plans for early-stage human trials projected for late 2023.
Collaborations and Partnerships
Over the years, NeuBase has established strategic partnerships to enhance its research capabilities:
- Collaboration with the University of Pittsburgh for RNA research.
- Partnership with the National Institutes of Health (NIH) for funding and support of therapeutic development.
These partnerships are aimed at accelerating the development of its therapeutics and expanding its technological expertise.
Recent Financial Data and Stock Performance
As of Q3 2023, NeuBase reported total assets of approximately $25 million. The company had cash and cash equivalents amounting to $10 million. The total liabilities were recorded at $5 million, resulting in a favorable current ratio of 5:1. The company's stock price has fluctuated, averaging around $1.50 per share.
| Year | Market Capitalization | IPO Amount | Cash & Equivalents | Total Assets | Total Liabilities |
|---|---|---|---|---|---|
| 2018 | N/A | N/A | N/A | N/A | N/A |
| 2020 | N/A | $15 million | N/A | N/A | N/A |
| 2021 | N/A | N/A | $8 million | $18 million | $3 million |
| 2023 | $20 million | N/A | $10 million | $25 million | $5 million |
Challenges and Future Outlook
NeuBase Therapeutics has faced challenges, including competition from other biotech firms in the gene therapy space and the complexities associated with obtaining regulatory approvals. Nevertheless, the company remains focused on advancing its clinical candidates and expanding its technological platform.
Conclusion of Developments
As NeuBase continues to navigate the biotechnology landscape, the emphasis remains on innovation and strategic collaborations to position itself as a leader in the development of therapies for genetic disorders.
A Who Owns NeuBase Therapeutics, Inc. (NBSE)
Ownership Structure
NeuBase Therapeutics, Inc. (NBSE) operates within the biotechnology sector, focusing on the development of targeted medicines for genetic diseases. As of the latest data, the ownership structure of the company is distributed among various institutional investors, individual shareholders, and company executives.
Major Shareholders
The following table outlines the major shareholders of NeuBase Therapeutics, Inc. along with their respective ownership percentages:
| Shareholder | Ownership Percentage | Type of Holder | Last Updated |
|---|---|---|---|
| BlackRock, Inc. | 10.4% | Institutional Investor | September 2023 |
| The Vanguard Group, Inc. | 9.5% | Institutional Investor | September 2023 |
| Arlington Capital Management | 6.3% | Institutional Investor | September 2023 |
| Philip A. Johnson | 4.1% | Individual Investor | September 2023 |
| Other Institutional Investors | 18.7% | Various | September 2023 |
| Insider Holdings | 5.2% | Company Executives | September 2023 |
Institutional Ownership
Institutional investors play a significant role in the ownership of NeuBase Therapeutics, holding a cumulative percentage of approximately 54.5% as of the latest records. Below is a summary of the institutional ownership:
| Institution | Number of Shares | Ownership Percentage | Market Value (USD) |
|---|---|---|---|
| BlackRock, Inc. | 1,500,000 | 10.4% | $5,700,000 |
| The Vanguard Group, Inc. | 1,350,000 | 9.5% | $5,100,000 |
| Arlington Capital Management | 800,000 | 6.3% | $3,240,000 |
| Other Institutions | 2,700,000 | 18.7% | $10,350,000 |
Executive Ownership
Executives and insiders of NeuBase Therapeutics, Inc. hold a combined total of about 5.2% of the company. Below is a table summarizing their holdings:
| Name | Title | Number of Shares | Ownership Percentage |
|---|---|---|---|
| Mr. Douglas G. A. McGarrity | CEO | 250,000 | 1.8% |
| Dr. J. Scott McCammon | Chief Scientific Officer | 150,000 | 1.1% |
| Ms. Jennifer T. Emit | CFO | 100,000 | 0.7% |
| Other Executives | Various | 200,000 | 1.6% |
Recent Stock Performance
As of the end of September 2023, NeuBase Therapeutics, Inc. shares are trading at approximately $3.80 per share, reflecting a market capitalization of roughly $51 million. Below is a summary of recent stock performance:
| Date | Share Price (USD) | Market Capitalization (USD) | 52-Week High (USD) | 52-Week Low (USD) |
|---|---|---|---|---|
| September 30, 2023 | $3.80 | $51 million | $8.00 | $2.50 |
Conclusion on Ownership
Ownership of NeuBase Therapeutics, Inc. is characterized by significant institutional investment alongside individual and insider holdings, indicating a diverse stakeholder base. This balance of shareholders plays a crucial role in the company's governance and strategic direction.
NeuBase Therapeutics, Inc. (NBSE) Mission Statement
Corporate Mission
NeuBase Therapeutics, Inc. is committed to pioneering the development of innovative therapies addressing the underlying causes of genetic disease through next-generation genetic medicines. The company utilizes its platform technology to create a new class of therapeutics that directly target and modify gene expression.
Core Values
- Innovation: Focus on advancing genetic medicine.
- Integrity: Uphold ethical standards in scientific research.
- Collaboration: Partnering for progress in healthcare solutions.
- Patient-Centric: Prioritizing patients in all company decisions.
Goals and Objectives
NeuBase aims to achieve the following objectives:
- Develop multiple therapeutic candidates for genetic disorders.
- Complete clinical trials by 2024.
- Expand strategic partnerships with biotech firms.
- Increase market share in gene editing technology.
Financial Overview
As of the latest quarterly report in Q3 2023, NeuBase Therapeutics, Inc. reported:
| Financial Metric | Amount (USD) |
|---|---|
| Revenue | $1.2 million |
| Net Loss | ($5.6 million) |
| Research & Development Expenses | $4.3 million |
| Cash and Cash Equivalents | $18.5 million |
Market Position
NeuBase operates within the competitive landscape of genetic medicine, with a focus on:
- mRNA therapeutics
- Gene silencing
- CRISPR-based technologies
The company's market cap as of October 2023 stands at approximately $100 million.
Recent Achievements
Key milestones reached include:
- Successful preclinical studies announced in September 2023.
- Initiation of Phase 1 clinical trials for lead candidate, NT-001.
- Partnership with major pharmaceutical companies for development financing.
Future Outlook
NeuBase is focused on expanding its product pipeline, targeting additional genetic disorders such as:
- Duchenne Muscular Dystrophy
- Cystic Fibrosis
- Huntington's Disease
The company projects to enter into at least two new collaborations by the end of 2024.
Summary of Key Financial Metrics
| Key Financial Metric | Q3 2023 Amount |
|---|---|
| Total Revenue | $1.2 million |
| Net Loss | ($5.6 million) |
| Cash Balance | $18.5 million |
| Market Capitalization | $100 million |
How NeuBase Therapeutics, Inc. (NBSE) Works
Overview of NeuBase Therapeutics
NeuBase Therapeutics, Inc. focuses on developing genetic medicines for rare diseases. The company employs its proprietary peptide nucleic acid (PNA) technology platform to design and develop targeted therapies for conditions caused by genetic mutations.
Business Model
The business model of NeuBase is built around the following core components:
- Research and Development of Genetic Therapeutics
- Collaboration with Academic Institutions and Pharmaceutical Companies
- Licensing Agreements for Future Commercialization
Technology Platform
NeuBase utilizes its proprietary technology, which is based on PNA, a synthetic analog of DNA that enhances the ability to target and modulate gene expression. This approach allows for:
- Effective delivery of genetic medicines
- Reduced off-target effects
- Improved stability and cellular uptake
Financial Performance
As of the third quarter of 2023, NeuBase reported the following financial metrics:
| Metric | Amount (USD) |
|---|---|
| Revenue | 0 |
| Operating Expenses | 4.2 million |
| Net Loss | 3.9 million |
| Cash and Cash Equivalents | 15.2 million |
| Total Assets | 18.1 million |
| Total Liabilities | 2.9 million |
Research and Development Pipeline
NeuBase's pipeline includes several key programs targeting specific genetic diseases:
- NT-0201 for Huntington's Disease
- NT-0101 for Duchenne Muscular Dystrophy (DMD)
- NT-0301 for Myotonic Dystrophy
Collaborations and Partnerships
The company has established collaborations with several academic and industry partners, which have led to the following agreements:
- Partnership with the University of Pennsylvania for research on genetic delivery.
- Collaboration with various pharmaceutical companies to develop targeted therapies.
Stock Performance
As of October 2023, the stock performance indicators for NeuBase Therapeutics are as follows:
| Indicator | Value |
|---|---|
| Stock Price | 0.72 |
| Market Capitalization | 20 million |
| 52-week High | 2.34 |
| 52-week Low | 0.60 |
Future Outlook
The future outlook for NeuBase Therapeutics involves strategic efforts to:
- Advance preclinical and clinical studies for pipeline candidates
- Seek additional funding to support R&D activities
- Expand partnerships for broader application of PNA technology
How NeuBase Therapeutics, Inc. (NBSE) Makes Money
Revenue Streams
NeuBase Therapeutics, Inc. primarily generates revenue through the following channels:
- Research Grants
- Collaborative Partnerships
- Product Licensing
- Equity Financing
Research Grants
NeuBase participates in various research initiatives funded by governmental and private agencies. As of 2022, it secured approximately $3.6 million in grants, contributing to its early-stage research programs focused on genetic disorders.
Collaborative Partnerships
Collaborations with larger pharmaceutical companies allow for significant funding. For instance, in 2021, NeuBase entered into a partnership with University of Pittsburgh which included an investment of $10 million over several years for joint research projects.
Product Licensing
Licensing agreements can provide substantial revenue. NeuBase has licensed its proprietary technology platforms, leading to estimated future revenue potential of approximately $20 million through milestone payments and royalties on sales.
Equity Financing
To fuel its operations and development, NeuBase has raised funds through equity financing. In September 2021, the company completed a public offering raising about $12 million, which was aimed at advancing its therapeutic pipeline.
Current Financial Overview
As of the latest quarterly report in Q3 2023, NeuBase reported the following financial figures:
| Financial Metric | Amount |
|---|---|
| Cash and Cash Equivalents | $15.2 million |
| Total Assets | $20.3 million |
| Total Liabilities | $5.1 million |
| Net Loss (Q3 2023) | ($2.1 million) |
| Revenue (2022) | $4.5 million |
Future Prospects
Looking forward, NeuBase is focused on advancing its preclinical and clinical programs which target genetic diseases. The potential market for its leading candidates is valued at over $100 billion, signifying a robust opportunity for revenue generation through successful product commercialization.
Market Comparisons
NeuBase's financial strategies can be compared to industry peers. Below is a table showcasing select financial metrics from similar companies as of 2022:
| Company | Market Cap (in million) | Revenue (in million) | Net Loss (in million) |
|---|---|---|---|
| NeuBase Therapeutics (NBSE) | $30 | $4.5 | ($6.3) |
| Ionis Pharmaceuticals | $8,000 | $260 | ($198) |
| Wave Life Sciences | $400 | $10 | ($80) |
| Regulus Therapeutics | $150 | $5 | ($20) |
Conclusion
Through a multifaceted approach encompassing grants, partnerships, licensing, and financing, NeuBase Therapeutics is positioned to capitalize on its innovative technologies, targeting significant market opportunities in the genetic therapies sector.
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