Oncorus, Inc. (ONCR) Bundle
A Brief History of Oncorus, Inc. (ONCR)
Foundation and Early Years
Foundation and Early Years
Oncorus, Inc. was founded in 2016 and is headquartered in Cambridge, Massachusetts. The company emerged from the laboratory of renowned scientist Dr. David H. Bartel, who played a vital role in its establishment.
Focus on Oncolytic Virus Therapeutics
Oncorus specializes in developing oncolytic virus therapies, which utilize modified viruses to target and destroy cancer cells. The company aims to revolutionize cancer treatment through its innovative approach.
Initial Funding and Growth
In 2017, Oncorus closed a Series A financing round, raising approximately $26 million. This funding was pivotal for advancing its research and development initiatives.
Key Collaborations
Oncorus has established collaborations with various research institutions and biotech companies. In 2019, it partnered with Harvard University to explore potential therapeutic applications of its platform.
| Year | Funding Amount | Collaboration Partner | Phase of Clinical Trials |
|---|---|---|---|
| 2017 | $26 million | N/A | N/A |
| 2019 | N/A | Harvard University | N/A |
| 2021 | $75 million | N/A | Phase 1 |
| 2022 | $50 million | University of Pennsylvania | Phase 1/2 |
Public Offering
Oncorus went public in 2021 under the ticker symbol ONCR. The Initial Public Offering (IPO) raised approximately $75 million, significantly boosting its capital for ongoing and future projects.
Recent Developments
In 2023, Oncorus announced positive results from its ongoing clinical trial for its lead candidate, ONCR-021, demonstrating favorable safety and efficacy profiles in patients with advanced cancers.
Financial Performance
As of the second quarter of 2023, Oncorus reported approximately $30 million in cash reserves. Its operational expenditures for the first half of 2023 were approximately $20 million.
| Financial Metric | Q2 2023 | H1 2023 | Year-End 2022 |
|---|---|---|---|
| Cash Reserves | $30 million | $30 million | $60 million |
| Operational Expenditures | $10 million | $20 million | $40 million |
| Net Income | -$8 million | -$16 million | -$32 million |
| Stock Price (as of August 2023) | $6.50 | N/A | $8.00 |
Pipeline and Future Directions
Oncorus has an ambitious pipeline focusing on multiple candidates, including ONCR-021 and ONCR-002. The company aims to enter Phase 2 trials for several candidates within the next year.
Conclusion of the Historical Overview
Oncorus, Inc. continues to leverage its innovative oncolytic virus platform as it advances its development of transformative cancer therapies. With strong backing and a robust research agenda, it stands poised for significant impact in the oncology field.
A Who Owns Oncorus, Inc. (ONCR)
Ownership Structure
As of the latest filings, Oncorus, Inc. (ONCR) has the following significant shareholders:
| Shareholder | Ownership Percentage | Shares Owned | Type of Ownership |
|---|---|---|---|
| Institutional Investors | 67.2% | 9,034,004 | Common Stock |
| Insider Ownership | 15.5% | 2,088,000 | Common Stock |
| Retail Investors | 17.3% | 2,310,000 | Common Stock |
Major Institutional Shareholders
The top institutional shareholders of Oncorus, Inc. include:
| Institution | Shares Held | Ownership Percentage |
|---|---|---|
| BlackRock, Inc. | 1,203,500 | 9.1% |
| Vanguard Group, Inc. | 1,100,000 | 8.4% |
| State Street Corporation | 645,000 | 4.9% |
| Wellington Management Company | 420,000 | 3.2% |
Insider Ownership
Insider ownership plays a crucial role in the governance of Oncorus, Inc. The notable insiders include:
| Name | Position | Shares Owned |
|---|---|---|
| James F. Barlow | CEO | 1,000,000 |
| Maria C. Gonzalez | CTO | 500,000 |
| Linda T. Crane | CFO | 588,000 |
Recent Financial Performance
The financial health of Oncorus, Inc. can be summarized by examining their latest quarterly figures:
| Quarter | Revenue | Net Income | Operating Expenses |
|---|---|---|---|
| Q3 2023 | $2.1 million | ($4.5) million | $6.2 million |
| Q2 2023 | $1.8 million | ($4.0) million | $5.5 million |
| Q1 2023 | $1.5 million | ($3.8) million | $5.0 million |
Market Capitalization
As of October 2023, Oncorus, Inc. has a market capitalization of:
| Market Capitalization |
|---|
| $125 million |
Stock Performance
Oncorus, Inc.'s stock performance over the last year is as follows:
| Statistic | Value |
|---|---|
| 52-Week High | $15.25 |
| 52-Week Low | $7.10 |
| Current Price | $10.50 |
Conclusion on Ownership Dynamics
The ownership dynamics of Oncorus, Inc. reflect a blend of institutional influence and insider control, underscoring the company's strategic direction in the biopharmaceutical landscape.
Oncorus, Inc. (ONCR) Mission Statement
Company Overview
Oncorus, Inc. is a clinical-stage biotechnology company focused on developing and commercializing innovative treatments for cancer. The company is primarily engaged in the development of oncolytic virotherapy and has a proprietary platform designed to create therapies that enhance the immune response against tumors.
Mission Statement
The mission of Oncorus, Inc. is to utilize the power of the immune system to improve the lives of patients with cancer by developing transformative therapies. The company aims to deliver innovative, safe, and effective treatment options that address unmet medical needs in oncology.
Strategic Goals
- Develop cutting-edge therapies with a strong scientific foundation.
- Advance the clinical development of potential treatments for various cancer types.
- Cultivate strategic partnerships to enhance research and clinical capabilities.
- Ensure effective patient access to novel therapies.
Financial Data
As of the latest report, Oncorus, Inc. reported the following financial metrics:
| Fiscal Year | Total Revenue | Net Loss | Cash and Cash Equivalents | Market Capitalization |
|---|---|---|---|---|
| 2023 | $0 | $(15.4 million) | $48.3 million | $160 million |
| 2022 | $0 | $(13.2 million) | $63.1 million | $120 million |
| 2021 | $0 | $(11.0 million) | $66.9 million | $90 million |
Clinical Development Pipeline
Oncorus is advancing several key programs in clinical development, focusing on oncolytic virus therapies. The following is an overview of their pipeline:
| Product Candidate | Treatment Area | Phase of Development | Expected Milestone Date |
|---|---|---|---|
| ONCR-177 | Solid Tumors | Phase 1 | Q2 2024 |
| ONCR-GBM | Glioblastoma | Phase 1 | Q4 2024 |
| ONCR-500 | Multiple Cancers | Preclinical | Q1 2025 |
Partnerships and Collaborations
Oncorus seeks to expand its research and development capabilities through strategic partnerships. Some of their notable collaborations include:
- Collaboration with the National Cancer Institute (NCI) for the evaluation of oncolytic viruses.
- Partnership with various academic institutions for research on viral therapeutics.
- Engagements with pharmaceutical companies for potential co-development of therapies.
Commitment to Patients
Oncorus is dedicated to ensuring that its innovative therapies are accessible to patients. The company works to engage with patient advocacy groups and healthcare providers to streamline the process of bringing its products to market and to optimize treatment pathways for patients with cancer.
How Oncorus, Inc. (ONCR) Works
Company Overview
Oncorus, Inc. is a biotechnology company focused on developing oncolytic virus therapies for the treatment of cancer. The company aims to harness the power of viruses to selectively target and kill cancer cells while stimulating an immune response against tumors.
Business Model
Oncorus operates through a model that emphasizes both proprietary drug development and strategic partnerships. The company’s pipeline consists of multiple product candidates designed to treat various types of cancer, utilizing their proprietary platform technology.
Pipeline and Product Candidates
As of October 2023, Oncorus has several key product candidates in development:
| Product Candidate | Indication | Development Stage | Expected Milestones |
|---|---|---|---|
| ONCR-177 | Solid Tumors | Phase 1 | Investigational New Drug (IND) Filing Q4 2023 |
| ONCR-021 | Lung Cancer | Phase 2 | Data Readout Q1 2024 |
| ONCR-071 | Melanoma | Preclinical | IND Filing 2024 |
Financial Performance
As of September 30, 2023, Oncorus reported the following financial metrics:
| Metric | Amount (USD) |
|---|---|
| Total Revenue | $0 |
| Research and Development Expenses | $8.5 million |
| General and Administrative Expenses | $3.2 million |
| Net Loss for Q3 2023 | $11.7 million |
| Cash and Cash Equivalents | $50 million |
Stock Performance
Oncorus, Inc. (ONCR) shares are traded on the Nasdaq Stock Market. Below are key stock performance metrics as of October 2023:
| Metric | Value |
|---|---|
| Current Share Price | $4.25 |
| Market Capitalization | $125 million |
| 52-Week Range | $1.75 - $6.00 |
| Volume (Average) | 150,000 shares |
Collaborations and Partnerships
Oncorus has established collaborations with several research institutions and biotechnology companies to enhance its drug development capabilities. Key partnerships include:
- Collaboration with the University of Pennsylvania for oncolytic virus research.
- Partnership with Merck KGaA to explore combination therapies.
- Agreement with a leading cancer research center for clinical trial support.
Future Outlook
With a strong development pipeline and ongoing trials, Oncorus aims to advance its innovative therapies and enter new markets. Focus areas include:
- Expanding clinical trials for ONCR-177 in solid tumors.
- Advancing ONCR-021 through its Phase 2 trial.
- Potential partnerships for commercialization post-IND approval.
How Oncorus, Inc. (ONCR) Makes Money
Revenue Streams
Oncorus, Inc. primarily generates revenue through the development and commercialization of its immunotherapy products. The company focuses on oncolytic viruses and other viral therapeutic approaches targeting cancer treatments.
Product Pipeline
The company has a diverse product pipeline, with several candidates in various stages of clinical trials. The following table outlines their key product candidates and their respective stages:
| Product Candidate | Indication | Stage | Estimated Market Size |
|---|---|---|---|
| ONCR-177 | Solid Tumors | Phase 1 | $30 billion |
| ONCR-021 | Head and Neck Cancer | Phase 2 | $4 billion |
| ONCR-019 | Melanoma | Preclinical | $3 billion |
Partnerships and Collaborations
Oncorus actively engages in partnerships and collaborations with larger pharmaceutical companies and research institutions to enhance its research capabilities and expand its market reach. Recent collaborations have included:
- Collaboration with Merck KGaA for potential co-development of ONCR-177.
- Partnership with The University of Pittsburgh for research on viral oncolytics.
Funding and Financial Position
As of Q2 2023, Oncorus, Inc. reported total cash and cash equivalents of approximately $50 million. The company has raised funds through various mechanisms including:
- Initial public offering (IPO) in 2021, raising $70 million.
- Subsequent private placements totaling $30 million.
Market Trends and Competitive Landscape
The immunotherapy market is projected to grow significantly, with an expected CAGR of 11% from 2023 to 2030. Competitors in the space include:
| Company | Market Capitalization (as of Oct 2023) | Core Product |
|---|---|---|
| Moderna, Inc. | $35 billion | mRNA Therapeutics |
| Amgen Inc. | $126 billion | Biologics |
| Regeneron Pharmaceuticals | $70 billion | Monoclonal Antibodies |
Potential Revenue from Licensing Agreements
Licensing agreements are a growing revenue opportunity for Oncorus. Recent licensing deals have yielded potential milestone payments upwards of $150 million, depending on the successful development and commercialization of their product candidates.
Future Financial Projections
Analysts project that Oncorus could achieve revenue of $200 million by the year 2026, contingent on the successful outcomes of its clinical trials and market penetration strategies.
Conclusion on Financial Viability
With a strong pipeline, strategic partnerships, and a favorable market landscape, Oncorus, Inc. is positioned to capitalize on its innovative therapeutic offerings and navigate the competitive marketplace effectively.
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