Palisade Bio, Inc. (PALI) Bundle
A Brief History of Palisade Bio, Inc. (PALI)
Company Overview
Company Overview
Palisade Bio, Inc. (PALI) is a biotechnology company that specializes in developing therapies for conditions related to the gastrointestinal tract. The company was founded in 2020 and is headquartered in San Diego, California. Palisade Bio focuses on utilizing its proprietary technology to address unmet medical needs in the field of gastrointestinal diseases.
Key Milestones
- 2020: Established as a spin-off from the University of California, San Diego.
- 2021: Completed an IPO raising approximately $15 million.
- 2022: Initiated clinical trials for its lead product candidate, PB2452.
- 2023: Received FDA Fast Track designation for PB2452.
Product Pipeline
| Product Candidate | Indication | Status | Expected Milestone Date |
|---|---|---|---|
| PB2452 | Reversal of Anticoagulation | Phase 2 Clinical Trials | Q3 2024 |
| PB1046 | Gastrointestinal Motility Disorders | Preclinical | N/A |
| PB2356 | Acute Intestinal Injury | Preclinical | N/A |
Financial Performance
- Market Capitalization (as of Q3 2023): Approximately $50 million.
- 2022 Revenue: $3.5 million.
- 2023 Revenue (Projected): $4.5 million.
- Cash Reserves (as of Q3 2023): $10 million.
Research and Development
The company invests significantly in R&D for innovative solutions in gastrointestinal health. As of 2023, R&D expenditure is estimated at $7 million annually, accounting for approximately 65% of total expenses.
Collaborations and Partnerships
- Partnership with the University of California, San Diego for ongoing research.
- Collaboration with several pharmaceutical companies to enhance drug development.
Shareholder Information
| Shareholder Type | Percentage Ownership |
|---|---|
| Institutions | 35% |
| Retail Investors | 60% |
| Insiders | 5% |
A Who Owns Palisade Bio, Inc. (PALI)
Shareholder Composition
As of the latest filing, the major shareholders of Palisade Bio, Inc. (PALI) are as follows:
| Shareholder | Ownership Percentage | Number of Shares |
|---|---|---|
| BlackRock, Inc. | 6.75% | 2,500,000 |
| Vanguard Group, Inc. | 5.90% | 2,200,000 |
| State Street Corporation | 4.25% | 1,600,000 |
| Joseph K. Oehl, Jr. | 3.10% | 1,150,000 |
| Kestrel Investment Management Corp. | 2.55% | 950,000 |
Institutional Ownership
Institutional ownership statistics highlight the degree of institutional investment in Palisade Bio:
| Institution | Ownership Percentage | Number of Shares Held |
|---|---|---|
| BlackRock Fund Advisors | 6.75% | 2,500,000 |
| Vanguard Total Stock Market Index Fund | 5.90% | 2,200,000 |
| State Street Global Advisors | 4.25% | 1,600,000 |
| Geode Capital Management, LLC | 2.80% | 1,050,000 |
| Invesco Ltd. | 2.45% | 900,000 |
Management Ownership
Management's stake in Palisade Bio represents confidence in the company's future:
| Name | Position | Ownership Percentage | Number of Shares |
|---|---|---|---|
| Mark S. S. H. A. M. R. T. | CEO | 1.20% | 450,000 |
| Jane Doe | CFO | 1.00% | 375,000 |
| John Smith | COO | 0.85% | 320,000 |
| Emily Johnson | CSO | 0.60% | 225,000 |
| Robert Brown | VP of Development | 0.50% | 188,000 |
Recent Stock Performance
The stock performance of Palisade Bio provides insights into market perception:
- Current Stock Price: $3.75
- 52-Week High: $5.00
- 52-Week Low: $1.90
- Market Capitalization: $150 million
- Average Daily Volume: 200,000 shares
Major Events Affecting Ownership
Several recent events have influenced the ownership structure, including:
- Recent equity financing totaling $30 million.
- Strategic partnerships with larger pharmaceutical companies.
- Board of Directors reshuffle which increased insider ownership.
Palisade Bio, Inc. (PALI) Mission Statement
Company Overview
Palisade Bio, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies for patients suffering from gastrointestinal diseases and conditions. The primary approach involves leveraging the company’s proprietary platform technology to enhance drug efficacy and safety.
Mission Statement
The mission of Palisade Bio is to develop and deliver innovative therapeutics that significantly improve the management of patients with gastrointestinal complications and enhance their quality of life. The company aims to be at the forefront of gastrointestinal medicine through rigorous scientific research and commitment to patient care.
Strategic Focus Areas
- Drug Development: Focus on novel therapeutics that address unmet medical needs.
- Patient-Centric Approach: Prioritizing patient outcomes and safety in all aspects of development.
- Partnerships: Collaborating with leading research institutions and other biotechnology companies to accelerate innovation.
Financial Overview
As of Q3 2023, Palisade Bio reported the following financial data:
| Financial Metric | Amount (in millions) |
|---|---|
| Revenue | $2.1 |
| Net Loss | ($15.8) |
| Cash and Cash Equivalents | $7.5 |
| Total Assets | $20.3 |
| Total Liabilities | $12.9 |
Market Position and Competitive Edge
Palisade Bio positions itself uniquely within the biotechnology sector by utilizing its innovative platform technology that specifically targets gastrointestinal diseases. The company’s competitive edge lies in:
- Proprietary Technology: Development of formulations that enhance drug delivery and absorption.
- Clinical Trials: Ongoing Phase 2 studies for lead candidates, focusing on efficacy and safety.
- Regulatory Strategy: Proactive engagement with regulatory agencies to facilitate faster approval processes.
Recent Developments
In 2023, Palisade Bio achieved several significant milestones:
- Initiation of a Phase 2 clinical trial for its lead product candidate.
- Strategic partnership with a leading pharmaceutical company to co-develop a new therapeutic.
- Securing a $10 million grant from the National Institutes of Health for research on gastrointestinal conditions.
Commitment to Innovation
Palisade Bio remains committed to ongoing research and development to drive innovation in gastrointestinal therapeutics. The company focuses on understanding the complexities of gastrointestinal diseases to tailor effective solutions for patients.
Conclusion
Palisade Bio’s mission centers on the development of effective treatments for gastrointestinal diseases, commitment to patient care, and continuous innovation in biopharmaceutical research.
How Palisade Bio, Inc. (PALI) Works
Company Overview
Palisade Bio, Inc. (PALI) is a clinical-stage biopharmaceutical company focused on developing treatments to manage the complications of surgery and to enhance recovery. Founded in 2019, the company is based in California and leverages proprietary drug delivery technologies to deliver therapeutic agents locally at the site of surgery.
Business Model
The business model of Palisade Bio revolves around the development of its lead product candidate, PB-201, which is designed to minimize post-operative complications and promote healing. The model includes:
- Research and Development: Allocation of funds towards clinical trials and drug development.
- Partnerships: Collaborations with larger pharmaceutical companies for co-development and distribution.
- Intellectual Property: Focus on securing patents for innovative drug delivery technologies.
Financial Performance
As of the latest financial report for the year ending December 31, 2022, Palisade Bio reported:
| Financial Metrics | Amount (USD) |
|---|---|
| Total Revenue | $0 |
| Research and Development Expenses | $6.4 million |
| General and Administrative Expenses | $2.1 million |
| Net Loss | $8.5 million |
| Cash and Cash Equivalents (as of December 31, 2022) | $10.0 million |
Product Pipeline
The company’s product pipeline includes several candidates aimed at improving surgical outcomes:
| Product Candidate | Indication | Status |
|---|---|---|
| PB-201 | Post-operative complications | Phase 2 Clinical Trials |
| PB-301 | Localized delivery of therapeutics | Pre-Clinical |
| PB-401 | Chronic wound management | Pre-Clinical |
Market Potential
The addressable market for surgical recovery and management of post-operative complications is substantial, estimated to reach:
- $300 billion globally by 2025.
- Growth rate of 7.5% CAGR from 2020 to 2025.
Stock Performance
As of October 2023, Palisade Bio's stock (PALI) is trading at:
| Stock Information | Value |
|---|---|
| Current Price | $1.50 |
| 52-Week High | $2.75 |
| 52-Week Low | $0.85 |
| Market Capitalization | $30 million |
Recent Developments
Recent news and developments include:
- Completion of Phase 1 clinical trial for PB-201 in Q2 2023.
- Initiation of collaborative research with a major academic institution in Q3 2023.
- Announcement of a $5 million funding round completed in early October 2023.
How Palisade Bio, Inc. (PALI) Makes Money
Revenue Streams
Revenue Streams
Palisade Bio, Inc. primarily engages in the development of therapeutic treatments for various diseases. Their revenue comes from:
- Licensing agreements with pharmaceutical companies.
- Partnerships for drug development.
- Sales of proprietary products.
Financial Performance
As of the latest financial report in Q2 2023, Palisade Bio reported revenues of $7.1 million for the six months ended June 30, 2023.
| Quarter | Revenue ($ million) | Expenses ($ million) | Net Income/Loss ($ million) |
|---|---|---|---|
| Q1 2023 | $3.5 | $4.2 | -$0.7 |
| Q2 2023 | $3.6 | $5.0 | -$1.4 |
Partnerships and Licensing Agreements
In 2023, Palisade Bio entered a partnership with a major pharmaceutical company for the co-development of a drug, which is projected to generate up to $20 million in upfront and milestone payments.
- Milestone payments for successful clinical trials.
- Percentage of sales from licensed products.
Product Pipeline
Palisade Bio is focused on developing therapeutics in various stages of clinical trials. Their key products include:
- PBI-200, currently in Phase 2 trials.
- PBI-100, undergoing preclinical studies.
The estimated market size for these products is valued at $1 billion collectively once they reach commercialization.
Market Presence
Palisade Bio's market capitalization as of October 2023 is approximately $50 million.
| Metric | Value |
|---|---|
| Market Capitalization ($ million) | $50 |
| Shares Outstanding (million) | 20 |
| Stock Price ($) | $2.50 |
Investment and Funding
As of 2023, Palisade Bio has raised a total of $30 million through various funding rounds, including private placements and public offerings.
- Series A Funding: $10 million
- Public Offering: $20 million
Conclusion
The financial outlook and growth potential of Palisade Bio rely heavily on successful drug development, strategic partnerships, and market expansion.
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