Silverback Therapeutics, Inc. (SBTX): history, ownership, mission, how it works & makes money

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Silverback Therapeutics, Inc. (SBTX) Information


A Brief History of Silverback Therapeutics, Inc. (SBTX)

Foundation and Early Years

Silverback Therapeutics, Inc. was founded in 2016, focusing on developing targeted therapies for cancer and other serious diseases. The company's proprietary platform is known as the Sulfated Glycosaminoglycan (sGAG) technology, which aims to enhance therapeutic delivery.

Initial Funding and Financial Growth

Silverback Therapeutics raised $30 million in a Series A funding round in 2017, led by several venture capital firms, including Atlas Venture and Intel Capital. In 2020, the company completed a Series B financing round, securing an additional $65 million.

Year Funding Round Amount Raised ($) Key Investors
2017 Series A 30,000,000 Atlas Venture, Intel Capital
2020 Series B 65,000,000 Various Venture Capital Firms

Public Offering and Market Performance

Silverback Therapeutics went public on April 2, 2021, through an IPO, raising over $150 million. The initial share price was set at $16, and the stock debuted on the NASDAQ under the ticker symbol SBTX.

Therapeutic Programs and Pipeline

The company's lead product candidate, SBTX-101, is a treatment for solid tumors. As of the latest updates, it has entered Phase 1 clinical trials. Additionally, Silverback is developing SBTX-102 and SBTX-103, targeting various forms of cancer.

Product Candidate Target Indication Development Phase
SBTX-101 Solid Tumors Phase 1
SBTX-102 Breast Cancer Preclinical
SBTX-103 Prostate Cancer Preclinical

Recent Financial Performance

As of the second quarter of 2023, Silverback Therapeutics reported total cash and cash equivalents of approximately $90 million. This financial position is expected to fund operations into mid-2025.

For the fiscal year 2022, the company reported a revenue of $12 million, primarily from collaboration agreements.

Key Partnerships and Collaborations

Silverback has established collaborations with major pharmaceutical companies to enhance its drug development pipeline. Notable partnerships include:

  • Collaboration with AstraZeneca for the co-development of immunotherapy.
  • Partnership with Takeda Pharmaceuticals to leverage their expertise in drug delivery.
  • Joint venture with Pfizer targeting various oncology applications.

Market Position and Future Outlook

As of October 2023, SBTX has a market capitalization of approximately $500 million. Analysts forecast that the company will grow significantly, pending the outcomes of ongoing clinical trials and strategic partnerships.



A Who Owns Silverback Therapeutics, Inc. (SBTX)

Company Overview

Silverback Therapeutics, Inc. (SBTX) is a biotechnology company focused on developing therapeutics for cancer and autoimmune diseases. As a publicly traded company, its ownership is distributed among various institutional investors, individual shareholders, and company insiders.

Major Shareholders

The ownership structure of Silverback Therapeutics includes a mix of institutional and retail investors. The following table outlines the major shareholders and their respective ownership percentages as of the latest available data:

Shareholder Type Shareholder Name Ownership Percentage
Institutional Investor The Vanguard Group, Inc. 8.1%
Institutional Investor BlackRock, Inc. 7.5%
Institutional Investor JPMorgan Chase & Co. 5.9%
Institutional Investor State Street Corporation 5.2%
Insider William G. Greenberg (CEO) 2.3%
Insider David L. McDonald (CFO) 1.8%
Retail Investor Public Float 63.2%

Recent Financial Performance

As of the most recent financial report for Q2 2023, Silverback Therapeutics reported the following key financial figures:

Financial Metric Q2 2023 Amount
Total Revenue $0
Net Loss ($10.5 million)
Cash and Cash Equivalents $75 million
Market Capitalization $300 million
Stock Price (as of Q2 2023) $5.00

Stock Performance and Volume

Silverback Therapeutics' stock performance has shown variability. The stock's historical data reflects its trading volume and price fluctuations:

Date Closing Price Trading Volume
August 1, 2023 $4.80 150,000
September 1, 2023 $5.10 200,000
October 1, 2023 $5.00 180,000

Future Ownership Trends

According to analysts, the trends in institutional investment in Silverback Therapeutics show a potential increase as the company advances its clinical trials and product development. Increased interest from biotech-focused funds could further augment institutional ownership in the coming quarters.



Silverback Therapeutics, Inc. (SBTX) Mission Statement

Corporate Overview

Silverback Therapeutics, Inc. (SBTX) is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapies for patients with cancer and other serious diseases. The company's mission is to harness the potential of its proprietary therapeutic platforms to deliver transformational medicines that significantly improve patient outcomes.

Mission Statement

Silverback Therapeutics aims to improve the lives of patients by developing targeted therapies that precisely modulate immune and oncologic pathways. The mission is driven by a commitment to scientific excellence, patient-centricity, and ethical governance.

Core Values

  • Innovation: Dedication to advancing science and introducing novel therapeutic approaches.
  • Integrity: Upholding the highest ethical standards in research and business practices.
  • Collaboration: Fostering partnerships that enhance the development and delivery of therapies.
  • Patient Focus: Commitment to understanding and prioritizing patient needs and experiences.

Strategic Goals

  • Advance multiple clinical programs to clinical trial stages.
  • Optimize therapies for better efficacy and safety profiles.
  • Expand partnerships with research entities and commercial organizations.
  • Achieve regulatory milestones for product approvals.

Recent Financial Highlights

Metric Value
Market Capitalization $151.76 million
Revenue (2022) $7.76 million
Net Loss (2022) -$46.14 million
Cash and Cash Equivalents (Q2 2023) $61.2 million
R&D Expenses (2022) $40.03 million
General and Administrative Expenses (2022) $16.11 million

Clinical Development Pipeline

Silverback Therapeutics has a pipeline of candidates with potential applications in oncology and immunology. Their lead product candidate, SBTX-101, is currently in clinical trials for patients with advanced solid tumors.

Key Partnerships

  • Partnership with Merck: Focus on combination therapies utilizing Silverback's proprietary delivery platform.
  • Academic Collaborations: Engaging with leading institutions for innovative research and development.

Future Directions

The company is actively pursuing strategic collaborations and investments to accelerate the development of its clinical candidates. Emphasis is placed on expanding the therapeutic indications and enhancing delivery mechanisms to improve efficacy.



How Silverback Therapeutics, Inc. (SBTX) Works

Company Overview

Silverback Therapeutics, Inc. (SBTX) is a clinical-stage biotechnology company focusing on creating therapeutics that target and modulate the immune system to treat diseases, particularly cancer and autoimmune disorders. The company's proprietary platform aims at developing its product candidates based on the use of immune-targeted therapies.

Business Model

The business model of Silverback Therapeutics is primarily centered around its innovative therapeutic approach, which combines the use of proprietary antibodies and immune-modulating agents. This approach supports the development of both systemic and localized immune therapies.

The key components of its business model include:

  • Targeted Therapeutics: Focus on developing therapies for oncology and autoimmune diseases.
  • Collaborations: Partnerships with pharmaceutical companies for development and commercialization.
  • Intellectual Property: Strong emphasis on securing patents for proprietary technologies.

Key Products and Development Pipeline

Silverback’s lead product candidates include:

  • SBTX-101: An investigational immune-targeting therapy for solid tumors.
  • SBTX-201: Focused on autoimmune diseases.

Clinical Trials

The clinical progress of SBTX products can be showcased through a recent overview of clinical trial phases:

Product Candidate Indication Phase Enrollment Expected Completion
SBTX-101 Solid Tumors Phase 1 150 Q3 2024
SBTX-201 Autoimmune Diseases Phase 2 200 Q2 2025

Financial Performance

As of the latest financial report, Silverback Therapeutics has shown significant financial metrics:

  • Market Capitalization: Approximately $200 million.
  • Cash and Cash Equivalents: $60 million reported at the end of Q3 2023.
  • Q3 2023 Revenue: $0 million, indicating the company is still in the development phase without commercial products.

Partnerships and Collaborations

Silverback has established strategic partnerships to enhance product development:

  • Collaboration with the National Cancer Institute for research funding.
  • Partnership with major pharmaceutical companies for sharing resources and expertise.

Regulatory Landscape

Silverback operates under regulatory oversight from the FDA and other global health authorities. The company is currently navigating through IND (Investigational New Drug) applications for its lead candidates. Compliance with clinical trial regulations and maintaining Good Manufacturing Practices (GMP) is essential for SBTX’s operations.

Market Analysis

The oncology therapeutics market is projected to reach $300 billion by 2024, reflecting a CAGR of approximately 10%. Silverback’s focus in this high-growth market positions it strategically for future success.

Conclusion of Key Metrics

The metrics and data displayed in this chapter illustrate the operational focus and market positioning of Silverback Therapeutics, Inc.:

Metric Value
Market Size - Oncology $300 billion by 2024
Cash Reserves $60 million
Clinical Trials Enrollment 350 total for SBTX-101 and SBTX-201


How Silverback Therapeutics, Inc. (SBTX) Makes Money

Revenue Streams

Silverback Therapeutics, Inc. primarily generates revenue through various channels as part of its business model.

Partnerships and Collaborations

Silverback has established partnerships with larger biopharmaceutical companies for the development and commercialization of its therapeutics.

  • In 2020, Silverback entered into a collaboration with AbbVie, potentially worth up to $1.2 billion including upfront and milestone payments.
  • Another collaboration with Genentech was valued at $1.9 billion, focusing on cancer therapies.

Grants and Funding

The company has received substantial funding through grants and public offering.

  • In 2021, Silverback was awarded a $2 million grant from the National Institutes of Health (NIH) for its immunotherapy research.
  • A successful public offering in 2020 raised $161 million to advance its pipeline.

Clinical Trial Revenue

As part of biopharmaceutical development, Silverback engages in clinical trials, which bring in revenue through various funding mechanisms.

  • The company reported expenditures of $20.9 million on R&D for full-year 2022.
  • Projected revenue from successful trials could significantly boost finances depending on milestone achievements.

Product Sales and Future Projections

Silverback has a growing portfolio of therapeutic candidates that is expected to generate product sales upon successful commercialization.

  • Currently, the lead candidate SBTX-101 is in clinical trials and could generate estimated sales of up to $500 million annually if successful.
  • Market analysts project that the global market for immunotherapies could reach $108 billion by 2027.
Revenue Source Details Projected Amount ($)
Partnerships Collaborations with AbbVie and Genentech 3.1 billion
Grants and Funding NIH Grant and Public Offering 163 million
Clinical Trials R&D expenditures and potential milestone revenue 20.9 million
Product Sales Projected annual sales from SBTX-101 500 million

Market Capitalization and Stock Performance

The financial health of Silverback is reflected in its market cap and stock performance.

  • As of October 2023, the market capitalization of Silverback Therapeutics stands at approximately $290 million.
  • The stock price has fluctuated, with a 52-week range between $1.50 and $5.20.

Conclusion of Financial Strategy

In summary, Silverback Therapeutics monetizes through diverse revenue streams, collaborations, and clinical advancements, positioning itself for future growth.

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