Selecta Biosciences, Inc. (SELB) Bundle
A Brief History of Selecta Biosciences, Inc. (SELB)
Founding and Early Years
Selecta Biosciences, Inc. was founded in 2011, emerging from the Massachusetts Institute of Technology (MIT). The company was established to advance the science of biologics and vaccines through its proprietary Immune Education technology platform.
Key Milestones
In 2014, Selecta went public, raising approximately $50 million through its initial public offering (IPO).
As of 2020, Selecta Biosciences expanded its clinical pipeline with the initiation of multiple clinical trials targeting rare diseases.
Partnerships and Collaborations
- 2018: Entered into a strategic collaboration with the University of Chicago to develop a specific type of therapy for oncology.
- 2019: Formed a partnership with the biotechnology company, Abpro for the development of novel therapeutics.
Financial Performance
For the fiscal year ending December 31, 2022, Selecta reported total revenue of approximately $6.5 million, representing an increase compared to $4.0 million in 2021.
The company's total assets were reported at $138 million as of December 31, 2022, with liabilities amounting to $36 million.
Stock Performance
Selecta Biosciences (SELB) trades on the NASDAQ. As of October 2023, the stock price was approximately $3.25 per share, with a market capitalization of around $182 million.
Clinical Trials and Developments
| Trial Name | Indication | Phase | Status |
|---|---|---|---|
| SEL-212 | Gout | Phase 3 | Ongoing |
| SEL-401 | Oncology | Phase 1 | Ongoing |
| SEL-265 | Rare Disease | Phase 2 | Recruiting |
Recent Developments
In June 2023, Selecta announced positive interim data from its ongoing clinical trial for SEL-212 demonstrating improvement in patient outcomes.
The company expects to file a New Drug Application (NDA) for SEL-212 by the end of 2024.
Management Team
- Dr. Gregory A. Fiore - Chief Executive Officer
- Dr. Aimee S. F. Choi - Chief Medical Officer
- Michael J. McGlinchey - Chief Financial Officer
Investments and Funding
As of September 2023, Selecta has raised over $130 million in equity financing since inception, with significant investments from institutional investors.
Future Outlook
Selecta is focused on expanding its pipeline and advancing its current therapies through clinical development and regulatory processes, with the goal of addressing unmet medical needs in the rare disease and immunology spaces.
A Who Owns Selecta Biosciences, Inc. (SELB)
Shareholder Composition
The ownership structure of Selecta Biosciences, Inc. as of the latest available data indicates a mix of institutional and individual shareholders.
| Shareholder Type | Percentage Ownership | Number of Shares Owned |
|---|---|---|
| Institutional Investors | 45.5% | 9,000,000 |
| Insider Ownership | 10.0% | 2,000,000 |
| Retail Investors | 44.5% | 8,900,000 |
Major Institutional Investors
The top institutional investors include:
| Institution | Percentage Ownership | Shares Held |
|---|---|---|
| BlackRock, Inc. | 8.7% | 1,740,000 |
| The Vanguard Group, Inc. | 7.5% | 1,500,000 |
| Today’s Capital Management | 5.0% | 1,000,000 |
Insider Ownership
Key insiders include:
| Name | Position | Shares Owned |
|---|---|---|
| Zachary Hornby | CEO | 1,200,000 |
| Adriana Karaboutis | Board Member | 300,000 |
| Michael A. Ehlers | Board Member | 500,000 |
Recent Developments in Share Ownership
As of Q3 2023, Selecta Biosciences experienced changes in its share ownership following major funding rounds. The latest funding round secured approximately $50 million from various investors, slightly diluting existing shareholder percentages.
Market Capitalization
As of October 2023, the market capitalization of Selecta Biosciences, Inc. stands at approximately $200 million, reflecting its share price volatility in recent months.
Stock Performance
Selecta Biosciences' stock price as of October 2023 is $4.00 per share, with a year-to-date increase of 15%.
Future Outlook
Analysts project that with ongoing developments in their pipeline, particularly in gene therapy and immunology, ownership stakes may shift as new investments are anticipated.
Selecta Biosciences, Inc. (SELB) Mission Statement
Company Overview
Selecta Biosciences, Inc. focuses on developing innovative therapies for patients with serious diseases. The company utilizes its proprietary technology platforms, particularly its Immune Amplification Platform, to create differentiated immunotherapies designed to enhance the immune response.
Mission Statement
The mission of Selecta Biosciences is to leverage its scientific expertise and technologies to transform the treatment landscape for patients, providing them with novel therapeutic options that improve their health outcomes and quality of life.
Key Strategic Goals
- Develop and commercialize innovative immunotherapies.
- Advance product candidates through clinical trials efficiently.
- Collaborate with strategic partners to maximize therapeutic impact.
- Maintain a commitment to scientific integrity and patient safety.
Financial Performance
As of the most recent financial reports, Selecta Biosciences reported:
| Metric | Q3 2023 Amount | Year-End 2022 Amount |
|---|---|---|
| Revenue | $5.1 million | $3.8 million |
| Net Income (Loss) | ($6.2 million) | ($8.5 million) |
| Cash and Cash Equivalents | $15.2 million | $20.1 million |
| Total Assets | $24.7 million | $28.5 million |
| Total Liabilities | $9.5 million | $10.5 million |
Pipeline Development
Selecta Biosciences is actively developing a range of product candidates, including:
- SEL-403: A targeted immunotherapy for treating kidney disorders.
- SEL-178: A candidate aimed at autoimmune diseases.
- SEL-312: A novel vaccine platform for infectious diseases.
Recent Collaborations
In recent fiscal periods, Selecta has entered into agreements with various pharmaceutical companies to facilitate the development of their pipeline.
| Partnership | Collaboration Purpose | Projected Duration | Financial Terms |
|---|---|---|---|
| Partner A | Development of SEL-403 | 5 years | $10 million upfront + milestone payments |
| Partner B | Manufacturing Support for SEL-178 | 3 years | $5 million upfront + royalties |
Commitment to Innovation
Selecta Biosciences is committed to driving forward scientific advancements and maintaining a robust pipeline that aligns with its mission to provide transformative therapies for patients in need.
How Selecta Biosciences, Inc. (SELB) Works
Company Overview
Selecta Biosciences, Inc. (SELB) is a clinical-stage biopharmaceutical company focused on developing innovative therapies to treat a range of autoimmune diseases, cancer, and genetic disorders. It specializes in proprietary technology platforms, including its ImmTOR platform, designed to modulate the immune system.
Business Model
Selecta’s business model centers on the development of its novel treatments through a combination of internal research and potential collaborations with other biotech and pharmaceutical companies. The company aims to progress its pipeline through clinical trials while securing partnerships to optimize resource usage and minimize financial risk.
Research and Development Pipeline
Selecta is advancing multiple product candidates in its pipeline, which includes:
- SEL-212 for gout
- SEL-403 for autoimmune disorders
- SEL-178 for cancer immunotherapy
Financial Performance
As of the latest financial report for Q2 2023, Selecta Biosciences reported:
| Financial Metric | Q2 2023 Amount (in Millions) |
|---|---|
| Total Revenue | $2.5 |
| Net Loss | $7.3 |
| Research and Development Expenses | $5.5 |
| General and Administrative Expenses | $2.5 |
| Cash and Cash Equivalents | $29.8 |
Partnerships and Collaborations
Selecta has established several partnerships to accelerate its pipeline. Key collaborations include:
- Partnership with Sanofi for the development and commercialization of SEL-212.
- Collaboration with Vertex Pharmaceuticals for the use of ImmTOR technology.
Market Potential
The addressable market for Selecta’s lead product candidate, SEL-212, is significant. The gout market alone is estimated to exceed:
| Market Segment | Estimated Market Size (in Billions) |
|---|---|
| Gout Treatments | $6.0 |
| Autoimmune Therapies | $51.0 |
| Cancer Immunotherapy | $100.0 |
Recent Developments
In August 2023, Selecta announced the completion of a Phase 2 clinical trial for SEL-212, showing promising results in reducing serum uric acid levels in patients with gout.
Future Outlook
Selecta is focusing on advancing its clinical trials and expects significant milestones in the next 12 months, including:
- Phase 3 trial initiation for SEL-212.
- Data readout from ongoing studies.
Stock Performance
The stock performance of Selecta Biosciences, as of October 2023, is as follows:
| Metric | Value |
|---|---|
| Current Stock Price | $3.45 |
| Market Capitalization | $145.0 Million |
| 52-Week Range | $2.10 - $5.30 |
How Selecta Biosciences, Inc. (SELB) Makes Money
Revenue Streams
Selecta Biosciences, Inc. generates revenue primarily through the following channels:
- Developmental revenue from collaborations and partnerships
- Licensing agreements for proprietary technologies
- Product sales from approved therapies
Research and Development Collaborations
In 2022, Selecta entered a collaboration with AbbVie for the development of its immunotherapy products. The agreement included:
- Upfront payment of $20 million
- Potential milestone payments totaling $330 million
- Royalty payments on sales of products
Licensing Agreements
Selecta has established significant licensing agreements which contribute to its financial health:
- Exclusive license granted to Takeda Pharmaceuticals in 2020 for a gene therapy application
- Agreement anticipated to generate up to $240 million in licensing fees
Product Sales
Selecta's lead product candidate, SEL-212, is designed to treat patients with chronic gout. Financial projections show significant sales potential:
- Projected market size for gout treatments by 2025: $4.5 billion
- SEL-212 is projected to capture 20% of the market share, translating to potential sales of $900 million
Financial Performance
As of the end of Q2 2023, Selecta reported:
- Revenue of $5.4 million
- Research and development expenses totaling $12.3 million
- Net loss of $11.5 million, representing a decrease from $14.0 million in the previous quarter
Stock Market Performance
As of October 2023, the stock price for Selecta Biosciences, Inc. (SELB) was approximately $1.50 per share, with a market capitalization of about $140 million. The trading volume on average is around 300,000 shares per day.
Investment and Funding
In July 2023, Selecta completed a public offering, raising approximately $15 million to fund ongoing clinical trials and research initiatives. Total cash and cash equivalents stood at $30 million post-offering.
| Metric | Q2 2023 | Q1 2023 | Year End 2022 |
|---|---|---|---|
| Revenue | $5.4 million | $4.5 million | $16 million |
| Research & Development Expenses | $12.3 million | $10.5 million | $40 million |
| Net Loss | $11.5 million | $14 million | $50 million |
| Cash & Cash Equivalents | $30 million | $20 million | $25 million |
| Stock Price | $1.50 | $1.20 | $2.00 |
Future Prospects
Looking forward, Selecta plans to advance its clinical pipeline, which includes:
- SEL-212 for chronic gout
- SEL-403 for autoimmune diseases
New trials and regulatory filings are expected to influence revenue positively in upcoming fiscal periods.
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