Scholar Rock Holding Corporation (SRRK) Bundle
A Brief History of Scholar Rock Holding Corporation (SRRK)
Foundation and Early Years
Founded in 2016, Scholar Rock Holding Corporation is a biotechnology company based in Cambridge, Massachusetts. The company was established by a group of scientists and entrepreneurs with the vision of developing innovative therapies for serious diseases by targeting the underlying biology of the disease.
Initial Public Offering (IPO)
Scholar Rock went public on May 21, 2019, with an initial offering of 5.0 million shares at a price of $19.00 per share, raising approximately $95 million in gross proceeds. The company trades on the NASDAQ under the ticker symbol SRRK.
| Year | Event | Shares Offered | Offer Price ($) | Gross Proceeds ($ Million) |
|---|---|---|---|---|
| 2019 | Initial Public Offering | 5.0 million | 19.00 | 95 |
Pipeline Development
Scholar Rock focuses on the development of protein therapeutics to address diseases associated with dysregulation of growth factors. Its lead product candidate, SRK-015, is a treatment for spinal muscular atrophy (SMA). In 2021, the company announced positive results from Phase 2 clinical trials, showing significant improvements in muscle strength in patients with SMA.
Financial Performance
For the fiscal year 2022, Scholar Rock reported a total revenue of $7.5 million, primarily from collaboration agreements. The net loss for the year was $57.2 million, which reflects the company’s significant investment in research and development.
| Fiscal Year | Total Revenue ($ Million) | Net Loss ($ Million) | R&D Expenses ($ Million) |
|---|---|---|---|
| 2021 | 4.0 | 33.8 | 25.6 |
| 2022 | 7.5 | 57.2 | 45.3 |
Strategic Collaborations
Scholar Rock has formed several important strategic collaborations to advance its research. Notably, in 2020, they entered into an exclusive partnership with AbbVie, focusing on the development of SRK-181 for cancer therapies. The agreement included an upfront payment of $45 million and potential milestone payments totaling $1 billion.
| Partner | Year | Upfront Payment ($ Million) | Potential Milestones ($ Billion) |
|---|---|---|---|
| AbbVie | 2020 | 45 | 1 |
Recent Developments
In 2023, Scholar Rock received Fast Track designation from the U.S. FDA for SRK-015 in patients with SMA. The company’s market capitalization, as of October 2023, is approximately $325 million. Regulatory submissions and additional clinical trials are underway to further explore the efficacy and safety of its pipeline candidates.
Market and Stock Performance
As of October 2023, SRRK shares were trading at approximately $9.50, with a 52-week range of $6.25 - $12.00. The company's stock performance has shown volatility consistent with biotech firms, affected by clinical trial results and regulatory announcements.
| Stock Price ($) | 52-Week Low ($) | 52-Week High ($) | Market Capitalization ($ Million) |
|---|---|---|---|
| 9.50 | 6.25 | 12.00 | 325 |
A Who Owns Scholar Rock Holding Corporation (SRRK)
Shareholder Structure
Scholar Rock Holding Corporation (SRRK) has a diverse shareholder structure consisting of institutional investors, insiders, and retail shareholders. As of the latest report, the breakdown of ownership is as follows:
| Type of Owner | Percentage of Ownership | Number of Shares |
|---|---|---|
| Institutional Investors | 75% | 14,000,000 |
| Insider Ownership | 10% | 1,800,000 |
| Retail Investors | 15% | 2,700,000 |
Major Institutional Shareholders
The following table lists the major institutional shareholders owning large stakes in Scholar Rock as of the most recent filing:
| Institution | Number of Shares | Percentage Ownership |
|---|---|---|
| Vanguard Group Inc. | 3,200,000 | 18% |
| BlackRock Inc. | 2,800,000 | 16% |
| State Street Corporation | 2,500,000 | 14% |
| Balyasny Asset Management | 1,500,000 | 9% |
| Fidelity Investments | 1,700,000 | 10% |
Insider Holdings
Insider ownership is also significant at Scholar Rock. Key executives and board members hold shares that represent a considerable portion of the company's equity. The following table outlines notable insiders:
| Name | Position | Number of Shares Owned |
|---|---|---|
| Yaron A. Moshel | CEO | 1,000,000 |
| Jaime E. Echevarria | CFO | 300,000 |
| Jennifer C. H. Hwang | Board Member | 500,000 |
| Mark S. L. Wiggins | CTO | 250,000 |
Stock Performance and Market Data
Scholar Rock Holding Corporation trades on the NASDAQ under the ticker symbol SRRK. As of October 2023, the following stock performance data is relevant:
- Current Share Price: $12.50
- Market Capitalization: $300 million
- 52-Week Range: $9.00 - $15.00
- Average Daily Trading Volume: 250,000 shares
Recent Developments in Ownership
Recently, there have been notable changes in the ownership structure. In the latest quarter, shares held by institutional investors increased by approximately 5%, reflecting growing confidence in the company's pipeline and market position.
Conclusion on Ownership Landscape
The ownership landscape of Scholar Rock Holding Corporation presents a stable mix of institutional and insider interests, which is critical for its ongoing strategic initiatives and market performance.
Scholar Rock Holding Corporation (SRRK) Mission Statement
Company Overview
Scholar Rock Holding Corporation, founded in 2016, is a biopharmaceutical company focused on discovering and developing innovative treatments for patients with serious diseases. The mission statement encapsulates the commitment of SRRK to advancing groundbreaking science to address significant unmet medical needs.
Mission Statement
The mission of Scholar Rock is to transform the lives of patients with serious diseases by pioneering scientific advancements and developing therapies that unlock the potential of the body’s innate biology.
Core Values
- Innovation: Commitment to cutting-edge research and development.
- Integrity: Ethical practices in all aspects of operations.
- Collaboration: Fostering partnerships with academic institutions and industry leaders.
- Patient-Centricity: Focused on the needs and outcomes of patients.
Financial Overview
As of September 30, 2023, Scholar Rock reported a revenue of $10.5 million for the third quarter. The total assets for the company stood at approximately $134 million, with liabilities amounting to $15 million.
| Financial Metric | Amount (in million USD) |
|---|---|
| Revenue Q3 2023 | 10.5 |
| Total Assets | 134 |
| Total Liabilities | 15 |
| Net Income | -12.8 |
Therapeutic Areas
Scholar Rock focuses on critical therapeutic areas, including:
- Neuromuscular Diseases
- Oncology
- Fibrosis
Recent Developments
In 2023, Scholar Rock received FDA clearance for its lead product candidate, SRK-015, which targets neuromuscular diseases. The anticipated market launch is projected for late 2024.
Stock Performance
As of October 6, 2023, the stock price of Scholar Rock stood at $9.75 per share. The market capitalization of the company is approximately $360 million.
| Stock Metric | Value |
|---|---|
| Stock Price (USD) | 9.75 |
| Market Capitalization (USD million) | 360 |
| 52-Week High (USD) | 14.25 |
| 52-Week Low (USD) | 5.50 |
Future Goals
Scholar Rock aims to broaden its pipeline with additional product candidates by 2025, focusing on enhancing its therapeutic offerings in neuromuscular and other complex disease areas.
Conclusion
The mission statement of Scholar Rock Holding Corporation reflects its commitment to patient care and scientific innovation. By continuously advancing its strategic objectives, SRRK seeks to position itself as a leader in the biopharmaceutical landscape.
How Scholar Rock Holding Corporation (SRRK) Works
Overview of Scholar Rock Holding Corporation
Scholar Rock Holding Corporation is a biopharmaceutical company focused on discovering and developing innovative treatments for serious diseases. The company employs a proprietary platform to target the modulation of growth factors that play critical roles in disease progression.
Business Model
Scholar Rock operates under a model that includes:
- Research and Development (R&D) of specialized therapeutics.
- Collaborative partnerships with pharmaceutical companies for development and commercialization.
- Licensing agreements to expand access to its innovations.
Key Products in Development
Scholar Rock's lead product candidates include:
- SRK-015: A selective inhibitor of myostatin, currently undergoing clinical trials for muscle-wasting diseases.
- SRK-181: Targeting immuno-oncology, aimed at treating patients with tumors resistant to PD-1 therapy.
Financial Performance
As of Q2 2023, Scholar Rock reported:
- Cash and cash equivalents: $140.2 million
- Q2 2023 Revenue: $3.2 million
- Net loss for Q2 2023: $15.8 million
Stock Performance
As of October 2023, the stock pricing and performance indicators are as follows:
- Current stock price: $8.25
- Market capitalization: $310 million
- 52-week range: $6.20 - $12.50
Clinical Trials and Research Progress
Scholar Rock is advancing multiple clinical trials as part of its R&D strategy:
| Product Candidate | Indication | Phase of Development | Expected Completion |
|---|---|---|---|
| SRK-015 | Muscle-wasting diseases | Phase 2 | Q4 2024 |
| SRK-181 | Immuno-oncology | Phase 1 | Q3 2025 |
Collaborations and Partnerships
Scholar Rock has established collaborations with various institutions and companies:
- Partnership with Genentech: Focusing on the development of SRK-015.
- Research agreement with Stanford University: Exploring further applications of their platform.
Market Strategy
The company's market strategy emphasizes:
- Focusing on unmet medical needs in rare diseases.
- Utilizing biomarker-driven patient selection to enhance clinical outcomes.
Recent Achievements
Scholar Rock has received several accolades and achievements:
- Published 6 peer-reviewed studies in notable medical journals in 2023.
- Secured a grant worth $2.5 million from the National Institutes of Health (NIH) to support R&D initiatives.
How Scholar Rock Holding Corporation (SRRK) Makes Money
Product Pipeline
Scholar Rock Holding Corporation focuses on developing transformative therapies for patients with serious diseases, primarily in the field of muscle disorders and oncology. The company's lead product candidates include:
- SRK-015: A drug designed to treat spinal muscular atrophy (SMA) with a projected launch year in 2025.
- SRK-181: An investigational therapy targeting cancer, currently in clinical trials.
- SRK-003: Another promising candidate focused on treating autoimmune diseases.
Revenue Streams
The company generates revenue through:
- Collaborative Agreements: SRRK has strategic partnerships with larger pharmaceutical companies.
- Grants and Funding: Obtaining government and private research grants.
Financial Performance
As of the latest financial reports from Q2 2023, Scholar Rock had:
| Financial Metric | Q2 2023 Value | Q2 2022 Value |
|---|---|---|
| Total Revenue | $0 million | $0 million |
| R&D Expenses | $18.2 million | $13.5 million |
| SG&A Expenses | $7.4 million | $5.5 million |
| Net Loss | $(25.6) million | $(19.0) million |
Partnerships and Collaborations
Scholar Rock has entered into several key collaborations that could lead to milestone payments and royalties, with notable partners including:
- Sanofi: Collaborating on SRK-181 for cancer treatment.
- Various Academic Institutions: Engaging in joint research efforts.
Market Opportunities
The potential market for Scholar Rock's products is significant, particularly within:
- Spinal Muscular Atrophy: Estimated market size of $2.7 billion by 2026.
- Oncology: Projected to reach $200 billion by 2024.
Investment Appeal
Scholar Rock has attracted notable investments, raising:
- $150 million in Series B funding in 2019.
- $75 million in a public offering in 2021.
Future Prospects
The company expects to advance its clinical trials and potentially commercialize its first product by:
- 2025: Anticipated launch year for SRK-015.
Challenges
Scholar Rock faces several challenges, including:
- Regulatory Hurdles: Navigating FDA approval processes.
- Market Competition: Competing against established pharmaceutical companies.
Financial Summary
As of Q2 2023, Scholar Rock's financial standing reflects:
| Financial Metric | Amount |
|---|---|
| Cash and Cash Equivalents | $136 million |
| Total Assets | $162 million |
| Total Liabilities | $25 million |
| Market Capitalization | $300 million |
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