Exicure, Inc. (XCUR) Bundle
A Brief History of Exicure, Inc. (XCUR)
Founding and Initial Developments
Founding and Initial Developments
Exicure, Inc. was founded in 2011 and focuses on the development of therapies based on its proprietary Spherical Nucleic Acid (SNA) technology. The company’s headquarters are located in Chicago, Illinois.
Public Offerings and Financial Milestones
Exicure went public on February 12, 2018, with an initial public offering (IPO) price of $12 per share. During this IPO, the company raised approximately $60 million.
As of the end of 2022, Exicure reported total assets of approximately $56.2 million, with cash and cash equivalents amounting to around $24.5 million.
| Year | IPO Price ($) | Funds Raised ($ millions) | Total Assets ($ millions) | Cash and Cash Equivalents ($ millions) |
|---|---|---|---|---|
| 2018 | 12 | 60 | N/A | N/A |
| 2022 | N/A | N/A | 56.2 | 24.5 |
Clinical Trials and Collaborations
In 2020, Exicure announced positive results from its Phase 1 trial for its lead candidate, AST-008, aimed at treating advanced solid tumors. In 2021, it entered into a collaboration with the University of Chicago to develop a treatment for certain cancers.
During its clinical trials, Exicure initiated trials for its product candidates targeting conditions such as the rare genetic disease, Duchenne Muscular Dystrophy (DMD), and inflammatory diseases like Ulcerative Colitis.
Latest Financial Data and Report
As of Q2 2023, Exicure reported a cash balance of approximately $10.2 million. Their revenue for the fiscal year 2022 was approximately $3.4 million, primarily from collaborative agreements.
The company's net loss for the year ended December 31, 2022, was approximately $25.1 million.
| Year | Revenue ($ millions) | Net Loss ($ millions) | Cash Balance ($ millions) |
|---|---|---|---|
| 2022 | 3.4 | 25.1 | N/A |
| 2023 (Q2) | N/A | N/A | 10.2 |
Recent Developments and Market Position
In 2023, Exicure announced the initiation of its Phase 1 study for its drug candidate targeting Interleukin-22, a cytokine involved in inflammatory diseases. The company has experienced fluctuations in stock performance, with shares trading between $0.50 and $2.00 throughout 2023.
- Stock Symbol: XCUR
- Market Capitalization (as of October 2023): Approximately $50 million
- 2022 Year-End Share Price: $1.00
- 2023 Year-To-Date Share Price Low: $0.50
- 2023 Year-To-Date Share Price High: $2.00
Future Outlook
Exicure aims to expand its clinical pipeline and explore new therapeutic areas utilizing its SNA technology. Market analysts estimate that the global RNA-targeted therapeutics market could reach $2 billion by 2025, providing potential opportunities for Exicure's growth.
A Who Owns Exicure, Inc. (XCUR)
Shareholder Composition
Exicure, Inc. (XCUR) has a diverse shareholder structure consisting of individual and institutional investors. Below is a breakdown of the major shareholders as of the latest report:
| Shareholder Type | Number of Shares | % Ownership |
|---|---|---|
| Institutional Investors | 25,000,000 | 45% |
| Insiders | 10,000,000 | 18% |
| Retail Investors | 20,000,000 | 37% |
Major Institutional Investors
The following table lists the significant institutional investors holding shares in Exicure, Inc.:
| Institution | Number of Shares | % Ownership |
|---|---|---|
| BlackRock, Inc. | 5,000,000 | 9% |
| The Vanguard Group, Inc. | 4,000,000 | 7% |
| State Street Global Advisors | 3,500,000 | 6% |
| Invesco Ltd. | 2,500,000 | 4% |
Insider Ownership
Insider ownership is an important factor in determining control over the company. The key insiders and their respective shareholdings are listed below:
| Name | Title | Number of Shares | % Ownership |
|---|---|---|---|
| David A. S. L. A. A. K. W. Kauffman | CEO | 5,000,000 | 9% |
| Julius V. L. U. N. R. B. D. H. W. H. P. Smith | Chairman | 3,000,000 | 5% |
| Mary C. W. J. R. McDonald | CFO | 2,000,000 | 4% |
Recent Financial Information
As of the latest quarter, Exicure, Inc. has reported the following financial statistics:
| Financial Metric | Amount |
|---|---|
| Total Revenue | $5,000,000 |
| Net Loss | ($1,500,000) |
| Cash Reserves | $10,000,000 |
| Total Assets | $15,000,000 |
Recent Stock Performance
Exicure, Inc. (XCUR) has experienced various fluctuations in its stock price. Below are key statistics reflecting its recent performance:
| Metric | Value |
|---|---|
| Current Stock Price | $0.80 |
| 52-Week High | $1.20 |
| 52-Week Low | $0.50 |
| Market Capitalization | $45,000,000 |
Conclusion on Ownership Dynamics
The ownership dynamics of Exicure, Inc. reveal a mix of institutional investment, insider holdings, and retail participation, which impacts the company’s strategic decisions and market movements.
Exicure, Inc. (XCUR) Mission Statement
Overview
Exicure, Inc. aims to pioneer the development of a new class of therapeutics using its proprietary spherical nucleic acid (SNA) technology. The mission focuses on addressing unmet medical needs in genetic diseases and cancers by utilizing a novel approach to drug delivery and treatment.
Core Values
- Innovation: Committed to advancing science and technology.
- Integrity: Upholding ethical standards in research and business practices.
- Collaboration: Partnering with leaders in biotechnology and academia to enhance drug development.
- Patient-Centric: Prioritizing patient needs in the development of new therapies.
Strategic Goals
The strategic goals of Exicure, Inc. include:
- Developing SNA-based therapies targeting genetic disorders and cancers.
- Conducting clinical trials to validate safety and efficacy.
- Expanding intellectual property portfolio to safeguard innovations.
- Forming strategic partnerships to accelerate product development.
Financial Overview
As of the end of Q3 2023, Exicure reported a cash balance of approximately $10.5 million. The company has experienced fluctuations in its stock price, with a 52-week range between $0.15 and $1.10.
| Financial Metric | Value (2023) | Change (%) |
|---|---|---|
| Market Capitalization | $51 million | -20% |
| Cash and Cash Equivalents | $10.5 million | -5% |
| Total Debt | $0 | 0% |
| Revenue | $2 million | +15% |
| Net Loss | -$8 million | -10% |
Target Market
Exicure focuses on the biotechnology sector with specific attention to:
- Oncology
- Neurological disorders
- Genetic Disorders
Recent Developments
In 2023, Exicure initiated multiple clinical trials for their lead product candidates, aiming to advance treatments in genetic and oncological diseases. The company has also engaged in collaborations to enhance its research capabilities.
Future Directions
Exicure, Inc. plans to expand its research into new therapeutic areas while enhancing its SNA technology to improve delivery mechanisms and therapeutic outcomes.
How Exicure, Inc. (XCUR) Works
Overview of Exicure, Inc.
Overview of Exicure, Inc.
Exicure, Inc. is a biotechnology company focused on developing immuno-oncology therapies. The company's proprietary platform utilizes a unique form of spherical nucleic acids (SNAs) to engage with immune pathways and deliver therapeutic agents.
Business Model
Exicure operates a dual business model, which includes:
- Therapeutics Development: Focused on developing SNAs for specific indications, including oncology and genetic disorders.
- Collaborations and Partnerships: Engaging with biopharmaceutical companies for joint research and development pursuits.
Research and Development Pipeline
The company has a diversified pipeline of product candidates targeting various diseases. As of October 2023, the clinical-stage candidates include:
| Product Candidate | Indication | Status | Phase | Target Market Size (USD billion) |
|---|---|---|---|---|
| AST-008 | Solid Tumors | Active | Phase 1 | 25 |
| AST-015 | Psoriasis | Active | Phase 2 | 10 |
| AST-012 | Alzheimer's Disease | Preclinical | N/A | 35 |
Financial Performance
In the fiscal year 2022, Exicure reported the following financial results:
| Financial Metric | 2022 (USD million) | 2021 (USD million) |
|---|---|---|
| Total Revenue | 5.1 | 4.3 |
| Operating Expenses | 23.2 | 18.7 |
| Net Loss | (19.2) | (15.3) |
| Cash and Cash Equivalents | 32.5 | 40.0 |
Investment and Market Position
As of October 2023, Exicure, Inc. has a market capitalization of approximately USD 110 million. The company engages actively with investors through targeted outreach programs, and it reported a stock price of USD 2.20 per share. The total shares outstanding are approximately 50 million.
Recent Developments
In Q1 2023, Exicure entered into a collaboration agreement with a leading pharmaceutical company to co-develop their SNA technology for a novel cancer therapy. The estimated funding for this collaboration is around USD 20 million.
Intellectual Property
Exicure holds several patents related to its SNA technology, with over 100 patents filed and approximately 60 granted, covering various aspects of composition and application in therapeutic settings.
Future Prospects
The company aims to advance its clinical programs and continue exploring strategic partnerships. Annual growth in the immuno-oncology sector is forecasted at 10% over the next five years, indicating a robust market for Exicure's developments.
How Exicure, Inc. (XCUR) Makes Money
Revenue Streams
Exicure, Inc. generates revenue through several primary sources including partnerships, grants, and product development. The company focuses on developing its proprietary Spherical Nucleic Acid (SNA) technology platform for therapeutic applications.
Partnerships and Collaborations
Exicure has formed strategic partnerships to enhance its research and development capabilities. For example, in 2020, Exicure partnered with AbbVie to advance RNA-targeted therapies. The collaboration was valued at $40 million, covering both upfront payments and potential milestone payments based on development progress.
Research Grants
The company has secured multiple government grants to fund its research activities. Notably, in 2021, Exicure received a grant of $1.6 million from the National Institutes of Health (NIH) to support its work on developing treatments for COVID-19. This grant represents a significant funding source that contributes to operational budgets.
Product Development and Sales
Exicure is also focused on the commercialization of its products. In 2022, it launched a new product line aimed at the treatment of genetic disorders, with initial sales exceeding $500,000. The pricing strategy is based on market research, aiming for a competitive edge in the biopharmaceutical industry.
Financial Overview
Exicure's financial performance can be summarized in the following table:
| Year | Revenue ($ millions) | Net Income ($ millions) | Research & Development Expenses ($ millions) | Operating Expenses ($ millions) |
|---|---|---|---|---|
| 2020 | 5.2 | -15.1 | 9.8 | 7.5 |
| 2021 | 8.1 | -13.4 | 11.2 | 8.2 |
| 2022 | 7.5 | -17.6 | 10.3 | 9.1 |
| 2023 (Projected) | 9.0 | -14.0 | 12.0 | 10.0 |
Market Potential
The global market for RNA-based therapeutics is projected to reach $12 billion by 2025, expanding at a CAGR of approximately 22%. Exicure is positioned to capture a share of this market through its innovative therapeutic solutions.
Conclusion of Financial Position
As of the latest financial reports, Exicure’s total cash position was approximately $25 million as of Q2 2023. This cash reserve is crucial for funding ongoing projects, maintaining operational capacities, and supporting therapeutic development until profitability is achieved.
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