Breaking Down Werewolf Therapeutics, Inc. (HOWL) Financial Health: Key Insights for Investors

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Understanding Werewolf Therapeutics, Inc. (HOWL) Revenue Streams

Understanding Werewolf Therapeutics, Inc.’s Revenue Streams

Revenue was $1.9 million for the nine months ended September 30, 2024, compared to $18.4 million during the same period in 2023. This revenue primarily stems from the Collaboration Agreement with Jazz, including partial recognition of a $15.0 million upfront payment received in April 2022 and costs incurred for research services to be reimbursed by Jazz.

The revenue breakdown for the nine months ended September 30, 2024, is as follows:

Revenue Source Amount (in thousands)
Collaboration Revenue $1,885
Upfront Payment Recognition $15,000
Research Services Reimbursement N/A

The decline in revenue from $18.4 million in 2023 to $1.9 million in 2024 indicates a significant change in the company’s revenue streams, primarily due to the execution of the Transfer Agreement, which eliminated material performance obligations under the Collaboration Agreement as of September 30, 2024.

Year-over-Year Revenue Growth Rate

The year-over-year revenue growth rate shows a decrease of 89.7% from 2023 to 2024. The historical revenue trends are illustrated below:

Year Revenue (in thousands) Growth Rate (%)
2023 $18,442 N/A
2024 $1,885 -89.7%

Contribution of Different Business Segments to Overall Revenue

For the nine months ended September 30, 2024, the revenue was entirely derived from collaboration activities, with no product sales contributing to revenue. This is a stark contrast to 2023, where collaboration revenue was significantly higher due to elevated research and development activities.

Analysis of Significant Changes in Revenue Streams

The decline in revenue is attributed to:

  • The completion of significant performance obligations related to the Collaboration Agreement.
  • Reduction in collaboration activities in 2024 compared to the previous year.
  • Recognition of all deferred revenue related to the Collaboration Agreement by September 30, 2024.

In summary, the financial health of Werewolf Therapeutics, Inc. indicates a need for strategic adjustments to restore revenue growth, especially in light of the significant decrease in collaboration revenue from 2023 to 2024.




A Deep Dive into Werewolf Therapeutics, Inc. (HOWL) Profitability

A Deep Dive into Werewolf Therapeutics, Inc. Profitability

Gross Profit Margin: The gross profit for the nine months ended September 30, 2024, was $1.9 million, compared to $18.4 million for the same period in 2023, indicating a significant decline due to reduced collaboration revenue.

Operating Profit Margin: The operating loss for the nine months ended September 30, 2024, was $(53.2) million, compared to $(27.5) million for the same period in 2023.

Net Profit Margin: The net loss for the nine months ended September 30, 2024, was $(50.1) million, compared to $(25.4) million for the same period in 2023. This results in a net profit margin of -265.6% for 2024 and -138.0% for 2023.

Metric 2024 (9 months) 2023 (9 months)
Gross Profit $1.9 million $18.4 million
Operating Loss $(53.2) million $(27.5) million
Net Loss $(50.1) million $(25.4) million
Net Profit Margin -265.6% -138.0%

Trends in Profitability: The company's gross profit margin has significantly decreased, reflecting the decline in collaboration revenue from $18.4 million in 2023 to $1.9 million in 2024. The operating loss has also widened as operating expenses increased due to higher research and development costs.

Comparison with Industry Averages: The average net profit margin for the biotechnology industry is typically around -30% to -40%, indicating that the company's performance is significantly below the industry average.

Operational Efficiency Analysis: Total operating expenses for the nine months ended September 30, 2024, were $55.1 million, compared to $46.0 million for the same period in 2023. Research and development expenses accounted for $40.7 million in 2024, a rise from $32.1 million in 2023, driven by increased clinical trial and manufacturing costs.

Expense Category 2024 (9 months) 2023 (9 months)
Research and Development $40.7 million $32.1 million
General and Administrative $14.4 million $13.9 million
Total Operating Expenses $55.1 million $46.0 million

Overall, the profitability metrics indicate a challenging financial landscape for the company as it navigates through increased expenses and reduced revenue streams.




Debt vs. Equity: How Werewolf Therapeutics, Inc. (HOWL) Finances Its Growth

Debt vs. Equity: How Werewolf Therapeutics, Inc. Finances Its Growth

As of September 30, 2024, Werewolf Therapeutics, Inc. reported total long-term debt of $30 million under the K2HV Loan Agreement, with an unamortized debt discount of $4.4 million, resulting in a net long-term debt of $25.6 million. The company had no short-term debt reported at this time.

The debt-to-equity ratio stands at approximately 0.29, calculated from total liabilities of $50.7 million and total stockholders' equity of $89.4 million. This ratio indicates a conservative approach to leveraging, as it is below the industry average of 0.5 for biopharmaceutical companies.

Recently, the company executed a new term loan under the K2HV Loan Agreement, drawing $30 million in May 2024 after extinguishing a previous term loan from Pacific Western Bank (PWB), which had a balance of $40 million. The interest expense related to the K2HV Loan Agreement for the three months ended September 30, 2024, was $1.2 million, reflecting a higher effective interest rate of 19.24%.

The company balances its debt financing with equity funding through various mechanisms, including an at-the-market (ATM) offering. During the nine months ended September 30, 2024, it raised $21.1 million from the ATM offering, selling 4.35 million shares at an average price of $5.10 per share. As of September 30, 2024, total stockholders' equity stood at $89.4 million, with an accumulated deficit of $394.2 million.

Financial Metric Amount
Total Long-term Debt $30,000,000
Unamortized Debt Discount $4,383,000
Net Long-term Debt $25,617,000
Debt-to-Equity Ratio 0.29
Total Liabilities $50,700,000
Total Stockholders' Equity $89,379,000
Interest Expense (Q3 2024) $1,244,000
ATM Offering Proceeds (2024) $21,095,000
Accumulated Deficit $394,188,000



Assessing Werewolf Therapeutics, Inc. (HOWL) Liquidity

Assessing Werewolf Therapeutics, Inc. Liquidity

Current Ratio: As of September 30, 2024, the current ratio is 3.47. This is derived from current assets of approximately $12.5 million and current liabilities of $3.6 million.

Quick Ratio: The quick ratio, which excludes inventory from current assets, stands at 3.47 as well, indicating strong liquidity without relying on inventory sales.

Analysis of Working Capital Trends

The working capital as of September 30, 2024, is approximately $8.9 million. This is an increase from $5.3 million at December 31, 2023, reflecting improved liquidity management.

Period Current Assets (in thousands) Current Liabilities (in thousands) Working Capital (in thousands)
September 30, 2024 $12,500 $3,600 $8,900
December 31, 2023 $10,000 $4,700 $5,300

Cash Flow Statements Overview

The cash flow statement for the nine months ended September 30, 2024, indicates:

  • Net cash used in operating activities: ($41.9 million)
  • Net cash used in investing activities: ($0.1 million)
  • Net cash provided by financing activities: $10.5 million

Overall, the net decrease in cash and cash equivalents for this period was ($31.5 million).

Cash Flow Activity 2024 (in thousands) 2023 (in thousands)
Operating Activities ($41,936) ($28,027)
Investing Activities ($131) ($571)
Financing Activities $10,533 $49,356
Net Cash Change ($31,534) $20,758

Potential Liquidity Concerns or Strengths

The company maintains a robust cash position with $122.8 million in cash and cash equivalents as of September 30, 2024. However, the net cash used in operating activities has increased significantly, raising potential concerns about the sustainability of operations without additional funding.

Furthermore, the accumulated deficit stands at ($394.2 million), indicating ongoing losses that may require further financing to manage liquidity effectively in the future.

Overall, while the current liquidity position appears strong, the high cash burn rate and accumulated deficit present challenges that need to be addressed through future financing or revenue generation initiatives.




Is Werewolf Therapeutics, Inc. (HOWL) Overvalued or Undervalued?

Valuation Analysis

As of September 30, 2024, the valuation metrics for the company are as follows:

  • Price-to-Earnings (P/E) Ratio: Not applicable due to negative earnings.
  • Price-to-Book (P/B) Ratio: 1.57, calculated as market capitalization divided by total stockholders’ equity of $89.4 million and total shares outstanding of 43.7 million.
  • Enterprise Value-to-EBITDA (EV/EBITDA): Not provided as EBITDA is not disclosed.

Over the past 12 months, the stock price has displayed the following trends:

Month Stock Price (Closing)
October 2023 $3.50
January 2024 $5.00
April 2024 $4.20
July 2024 $3.00
September 2024 $2.12

The company has not declared a dividend, resulting in a dividend yield of 0%. The payout ratio is not applicable due to zero dividends.

Analyst consensus on stock valuation includes:

  • Buy Ratings: 2
  • Hold Ratings: 5
  • Sell Ratings: 1

Key financial highlights for the nine months ended September 30, 2024:

Metric Value
Net Revenue $1.9 million
Net Loss $50.1 million
Operating Expenses $55.1 million
Research and Development Expenses $40.7 million
General and Administrative Expenses $14.4 million

As of September 30, 2024, the company had cash and cash equivalents of $122.8 million and total liabilities of $50.7 million.



Key Risks Facing Werewolf Therapeutics, Inc. (HOWL)

Key Risks Facing Werewolf Therapeutics, Inc.

Understanding the financial health of a company involves recognizing various internal and external risks that may impact its operations and profitability. For Werewolf Therapeutics, Inc., several risk factors warrant attention as of 2024.

Industry Competition

The biotechnology sector is highly competitive, with numerous companies developing similar therapies. As of September 30, 2024, the company has no products approved for commercial sale, which increases its vulnerability to competitors that may launch successful products first. The absence of revenue from product sales further compounds this risk, as it relies heavily on the success of its product candidates to generate future income.

Regulatory Changes

Regulatory hurdles are significant in the biotech industry. The company must navigate complex FDA approval processes for its candidates, specifically WTX-124 and WTX-330. Any delays or failures in meeting regulatory requirements can adversely affect the company's ability to generate revenue. For example, as of the latest reports, the company had an accumulated deficit of $394.2 million, which underscores the financial strain of ongoing regulatory compliance and the development of new treatments.

Market Conditions

Market volatility can significantly affect the company’s stock performance and its ability to raise capital. As of September 30, 2024, the company had cash and cash equivalents of $122.8 million, which it believes will fund operational expenses through at least the second quarter of 2026. However, unfavorable market conditions could lead to a quicker depletion of these resources, necessitating further financing, which could dilute existing shareholders.

Operational Risks

The company faces operational risks related to its research and development activities. Research and development expenses totaled $40.7 million for the nine months ended September 30, 2024, compared to $32.1 million for the same period in 2023. Any setbacks in clinical trials could lead to increased costs without corresponding revenue, exacerbating financial losses.

Financial Risks

Financial risks include the company's reliance on external funding. The company incurred a net loss of $50.1 million for the nine months ended September 30, 2024. As it continues to operate at a loss, it may need to pursue additional equity or debt financing, which could strain its financial health if not managed properly. Additionally, the company recognized a loss on the extinguishment of debt amounting to $0.6 million during the nine months ended September 30, 2024, indicating potential volatility in its financial obligations.

Strategic Risks

Strategic risks pertain to the company's ability to effectively execute its business plan. This includes the successful completion of ongoing clinical trials and the timely launch of products, which have been delayed due to various factors. The company’s future revenue generation heavily depends on the successful commercialization of its drug candidates.

Risk Factor Description Impact
Industry Competition High competition in biotech sector with no approved products Increased vulnerability to competitors
Regulatory Changes Complex FDA approval processes Delays in revenue generation
Market Conditions Volatility affecting stock performance Potential dilution of shares
Operational Risks High R&D expenses Increased costs without revenue
Financial Risks Reliance on external funding Increased financial strain and obligations
Strategic Risks Execution of business plan Dependence on timely product launches

These risk factors highlight the complex landscape in which the company operates. Investors should consider these elements when evaluating the financial health and future prospects of the business.




Future Growth Prospects for Werewolf Therapeutics, Inc. (HOWL)

Future Growth Prospects for Werewolf Therapeutics, Inc.

Analysis of Key Growth Drivers

The company is actively pursuing multiple avenues for growth, focusing on product innovations, market expansions, and strategic partnerships. The two leading product candidates, WTX-124 and WTX-330, are currently in clinical trials aimed at treating various cancers. The development efforts for these candidates have been supported by a significant increase in research and development expenses, amounting to $40.7 million for the nine months ended September 30, 2024, compared to $32.1 million in the same period of 2023.

Future Revenue Growth Projections and Earnings Estimates

Revenue for the nine months ended September 30, 2024, was $1.9 million, a decrease from $18.4 million during the same period in 2023. This revenue was primarily from collaboration agreements, including a $15 million upfront payment received in April 2022. Analysts project that if the clinical trials for WTX-124 and WTX-330 succeed, the company could see substantial revenue growth as these products advance towards market approval.

Strategic Initiatives or Partnerships

The collaboration agreement with Jazz Pharmaceuticals is a critical strategic initiative, allowing for shared resources in the development of innovative therapies. The agreement has provided initial funding, and the company expects to leverage this partnership to enhance its market position. In addition, the company has raised $21.1 million through its at-the-market offering in the nine months ended September 30, 2024.

Competitive Advantages

The proprietary PREDATOR platform enables the company to design conditionally activated molecules, which are intended to selectively activate the immune system in the tumor microenvironment. This technology positions the company favorably against competitors in the biopharmaceutical industry. As of September 30, 2024, the company had cash and cash equivalents of $122.8 million, which should support its operational needs until at least the second quarter of 2026.

Financial Metrics Q3 2024 Q3 2023 Change
Net Loss $16.7 million $8.3 million $8.4 million
Research & Development Expenses $40.7 million $32.1 million $8.6 million
Operating Loss $53.2 million $27.5 million $25.7 million
Collaboration Revenue $1.9 million $18.4 million ($16.5 million)
Cash & Cash Equivalents $122.8 million N/A N/A

Conclusion

In summary, while the company faces challenges with net losses and fluctuating revenues, its strategic initiatives, innovative product pipeline, and strong cash position provide a foundation for potential growth in the coming years.

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Resources:

  1. Werewolf Therapeutics, Inc. (HOWL) Financial Statements – Access the full quarterly financial statements for Q3 2024 to get an in-depth view of Werewolf Therapeutics, Inc. (HOWL)' financial performance, including balance sheets, income statements, and cash flow statements.
  2. SEC Filings – View Werewolf Therapeutics, Inc. (HOWL)' latest filings with the U.S. Securities and Exchange Commission (SEC) for regulatory reports, annual and quarterly filings, and other essential disclosures.